c-Ski inhibits the TGF-beta signaling pathway through stabilization of inactive Smad complexes on Smad-binding elements - Wikidata - thesis-toulmin - TriplyDB

c-Ski inhibits the TGF-beta signaling pathway through stabilization of inactive Smad complexes on Smad-binding elements

c-Ski inhibits the TGF-beta signaling pathway through stabilization of inactive Smad complexes on Smad-binding elements

http://www.wikidata.org/entity/Q24337860

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Arkadia induces degradation of SnoN and c-Ski to enhance transforming growth factor-beta signaling SKI and MEL1 cooperate to inhibit transforming growth factor-beta signal in gastric cancer cells An Id-like molecule, HHM, is a synexpression group-restricted regulator of TGF-beta signalling Decreased specific force and power production of muscle fibers from myostatin-deficient mice are associated with a suppression of protein degradation Key role for ubiquitin protein modification in TGFβ signal transduction TGF-β signaling in C. elegans SnoN is a cell type-specific mediator of transforming growth factor-beta responses c-Ski activates MyoD in the nucleus of myoblastic cells through suppression of histone deacetylases Transcriptional regulation of seprase in invasive melanoma cells by transforming growth factor-β signaling.Transforming growth factor-β induces transcription factors MafK and Bach1 to suppress expression of the heme oxygenase-1 gene.TGF-beta signaling in chondrocytes.Pocket protein function in melanocyte homeostasis and neoplasia.Clinical, agricultural, and evolutionary biology of myostatin: a comparative review The Ski protein can inhibit ligand induced RARalpha and HDAC3 degradation in the retinoic acid signaling pathway.Ski and SnoN, potent negative regulators of TGF-beta signaling.Ski protein levels increase during in vitro progression of HPV16-immortalized human keratinocytes and in cervical cancer.c-Ski, Smurf2, and Arkadia as regulators of TGF-beta signaling: new targets for managing myofibroblast function and cardiac fibrosis.Regulation of estrogen receptor signaling in breast carcinogenesis and breast cancer therapy.Crosstalk of TGF-β and estrogen receptor signaling in breast cancer.Transforming growth factor-β and atherosclerosis: interwoven atherogenic and atheroprotective aspects.c-Ski in health and disease.RB1CC1 protein positively regulates transforming growth factor-beta signaling through the modulation of Arkadia E3 ubiquitin ligase activity.Intracellular signaling of cardiac fibroblasts.The SKI proto-oncogene enhances the in vivo repopulation of hematopoietic stem cells and causes myeloproliferative disease.Structural Basis of Intracellular TGF-β Signaling: Receptors and Smads.Expression of Ski can act as a negative feedback mechanism on retinoic acid signaling.ZAS3 accentuates transforming growth factor β signaling in epithelial cells The phosphatidylinositol 3-kinase/Akt pathway regulates transforming growth factor-{beta} signaling by destabilizing ski and inducing Smad7.The mechanism of TGF-β/miR-155/c-Ski regulates endothelial-mesenchymal transition in human coronary artery endothelial cells.Antifibrotic properties of c-Ski and its regulation of cardiac myofibroblast phenotype and contractility.MiR-497∼195 cluster microRNAs regulate osteoblast differentiation by targeting BMP signaling.The Ski proto-oncogene regulates body composition and suppresses lipogenesis.Involvement of c-Ski oncoprotein in carcinogenesis of cholangiocacinoma induced by Opisthorchis viverrini and N-nitrosodimethylamine.Inhibition of retinoic acid receptor signaling by Ski in acute myeloid leukemia.Changes in DNA methylation induced by multi-walled carbon nanotube exposure in the workplace.Curcumin downregulates the expression of Snail via suppressing Smad2 pathway to inhibit TGF-β1-induced epithelial-mesenchymal transitions in hepatoma cells.Regulation of c-MYC transcriptional activity by transforming growth factor-beta 1-stimulated clone 22.USP4 inhibits SMAD4 monoubiquitination and promotes activin and BMP signaling.The Role of c-SKI in Regulation of TGFβ-Induced Human Cardiac Fibroblast Proliferation and ECM Protein Expression.Smad3-STAT3 crosstalk in pathophysiological contexts.

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P2860

c-Ski inhibits the TGF-beta signaling pathway through stabilization of inactive Smad complexes on Smad-binding elements

http://www.wikidata.org/entity/Q24337860

description

2004 nî lūn-bûn

@nan

2004 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի հունիսին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

@yue

2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

c-Ski inhibits the TGF-beta si ...... lexes on Smad-binding elements

@ast

c-Ski inhibits the TGF-beta si ...... lexes on Smad-binding elements

@en

c-Ski inhibits the TGF-beta si ...... lexes on Smad-binding elements

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c-Ski inhibits the TGF-beta si ...... lexes on Smad-binding elements

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type

label

c-Ski inhibits the TGF-beta si ...... lexes on Smad-binding elements

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c-Ski inhibits the TGF-beta si ...... lexes on Smad-binding elements

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c-Ski inhibits the TGF-beta si ...... lexes on Smad-binding elements

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c-Ski inhibits the TGF-beta si ...... lexes on Smad-binding elements

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prefLabel

c-Ski inhibits the TGF-beta si ...... lexes on Smad-binding elements

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c-Ski inhibits the TGF-beta si ...... lexes on Smad-binding elements

@en

c-Ski inhibits the TGF-beta si ...... lexes on Smad-binding elements

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c-Ski inhibits the TGF-beta si ...... lexes on Smad-binding elements

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c-Ski inhibits the TGF-beta si ...... lexes on Smad-binding elements

@en

P2093

Hiroyuki Suzuki

http://www.w3.org/2001/XMLSchema#string

Ken Yagi

http://www.w3.org/2001/XMLSchema#string

Kohei Miyazono

http://www.w3.org/2001/XMLSchema#string

Miki Kondo

http://www.w3.org/2001/XMLSchema#string

P2860

c-Ski acts as a transcriptional co-repressor in transforming growth factor-beta signaling through interaction with smads

Two short segments of Smad3 are important for specific interaction of Smad3 with c-Ski and SnoN

Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor beta growth arrest program.

Transforming growth factor-beta 1 modulates basic fibroblast growth factor-induced proteolytic and angiogenic properties of endothelial cells in vitro.

c-myc is a downstream target of the Smad pathway.

Alternatively spliced variant of Smad2 lacking exon 3. Comparison with wild-type Smad2 and Smad3.

Regulation of Smad7 promoter by direct association with Smad3 and Smad4.

Functional characterization of transforming growth factor beta signaling in Smad2- and Smad3-deficient fibroblasts.

P2888

P304

5068-5076

http://www.w3.org/2001/XMLSchema#string

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scholarly article

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10.1038/SJ.ONC.1207690

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29

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23

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2004-06-01T00:00:00Z

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8597016

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1011369399

http://www.w3.org/2001/XMLSchema#string

P698

15107821

http://www.w3.org/2001/XMLSchema#string

P921

SKI proto-oncogene