SHARPIN is an endogenous inhibitor of β1-integrin activation
about
Integrins β1 and β3 exhibit distinct dynamic nanoscale organizations inside focal adhesionsKIF14 negatively regulates Rap1a-Radil signaling during breast cancer progressionIdentification of novel integrin binding partners for calcium and integrin binding protein 1 (CIB1): structural and thermodynamic basis of CIB1 promiscuityGadkin negatively regulates cell spreading and motility via sequestration of the actin-nucleating ARP2/3 complexNF-κB, the first quarter-century: remarkable progress and outstanding questionsIntegrin trafficking at a glancePAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesionBeta 1-integrin-c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes.Structural Analysis of SHARPIN, a Subunit of a Large Multi-protein E3 Ubiquitin Ligase, Reveals a Novel Dimerization Function for the Pleckstrin Homology SuperfoldMolecular basis for specificity of the Met1-linked polyubiquitin signalDiverse functions of kindlin/fermitin proteins during embryonic development in Xenopus laevis.Detection of histone modifications at specific gene loci in single cells in histological sections.A proteomic approach reveals integrin activation state-dependent control of microtubule cortical targeting.Regulated delivery of molecular cargo to invasive tumour-derived microvesiclesThe kinetochore-dependent and -independent formation of the CDC20-MAD2 complex and its functions in HeLa cellsStructural and mechanical functions of integrins.Integrin αII b tail distal of GFFKR participates in inside-out αII b β3 activation.The primacy of β1 integrin activation in the metastatic cascade.Integrin αIIb-mediated PI3K/Akt activation in platelets.Transmembrane and Juxtamembrane Structure of αL Integrin in Bicelles.Structural mechanism of integrin inactivation by filamin.Mutually Exclusive Roles of SHARPIN in Integrin Inactivation and NF-κB Signaling.SHARPIN is a key regulator of immune and inflammatory responsesTargeting Integrin-Dependent Adhesion and Signaling with 3-Arylquinoline and 3-Aryl-2-Quinolone Derivatives: A new Class of Integrin AntagonistsRegulation of integrin-mediated adhesions.Discovery of the migrasome, an organelle mediating release of cytoplasmic contents during cell migration.The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signalingThe pathogenesis of chronic eosinophilic esophagitis in SHARPIN-deficient miceRad9 protein contributes to prostate tumor progression by promoting cell migration and anoikis resistance.Mena binds α5 integrin directly and modulates α5β1 function.Leukocyte arrest: Biomechanics and molecular mechanisms of β2 integrin activationSHARPIN controls regulatory T cells by negatively modulating the T cell antigen receptor complexMT1-MMP-dependent control of skeletal stem cell commitment via a β1-integrin/YAP/TAZ signaling axis.Role of Linear Ubiquitination in Health and DiseaseExpanding the Diversity of Imaging-Based RNAi Screen Applications Using Cell Spot Microarrays.SHARPIN regulates uropod detachment in migrating lymphocytes.Chronic proliferative dermatitis in Sharpin null mice: development of an autoinflammatory disease in the absence of B and T lymphocytes and IL4/IL13 signaling.Sharpin promotes hepatocellular carcinoma progression via transactivation of Versican expression.Ubiquitination in signaling to and activation of IKK.Integrin signaling in vascular function.
P2860
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P2860
SHARPIN is an endogenous inhibitor of β1-integrin activation
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
SHARPIN is an endogenous inhibitor of β1-integrin activation
@ast
SHARPIN is an endogenous inhibitor of β1-integrin activation
@en
SHARPIN is an endogenous inhibitor of β1-integrin activation
@en-gb
SHARPIN is an endogenous inhibitor of β1-integrin activation
@nl
type
label
SHARPIN is an endogenous inhibitor of β1-integrin activation
@ast
SHARPIN is an endogenous inhibitor of β1-integrin activation
@en
SHARPIN is an endogenous inhibitor of β1-integrin activation
@en-gb
SHARPIN is an endogenous inhibitor of β1-integrin activation
@nl
prefLabel
SHARPIN is an endogenous inhibitor of β1-integrin activation
@ast
SHARPIN is an endogenous inhibitor of β1-integrin activation
@en
SHARPIN is an endogenous inhibitor of β1-integrin activation
@en-gb
SHARPIN is an endogenous inhibitor of β1-integrin activation
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
SHARPIN is an endogenous inhibitor of β1-integrin activation
@en
P2093
Christopher S Potter
Elina Mattila
Janet A Askari
John P Sundberg
Juha K Rantala
Marko Salmi
Petra Laasola
Stefan Veltel
Teijo Pellinen
P2860
P2888
P304
P3181
P356
10.1038/NCB2340
P407
P5008
P577
2011-11-01T00:00:00Z
P5875
P6179
1031341122