Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX.
about
Exportin-5, a novel karyopherin, mediates nuclear export of double-stranded RNA binding proteins.N-terminal alpha-methylation of RCC1 is necessary for stable chromatin association and normal mitosis.Antagonistic effects of phorbol esters on insulin regulation of insulin-like growth factor-binding protein-1 (IGFBP-1) but not glucose-6-phosphatase gene expressionTwo novel phosphorylation sites on FKHR that are critical for its nuclear exclusionA novel heterodimerization domain, CRM1, and 14-3-3 control subcellular localization of the MondoA-Mlx heterocomplex.Protein kinase C phosphorylates ribosomal protein S6 kinase betaII and regulates its subcellular localization.Regulation of the Forkhead transcription factor AFX by Ral-dependent phosphorylation of threonines 447 and 451Importin-alpha mediates the regulated nuclear targeting of serum- and glucocorticoid-inducible protein kinase (Sgk) by recognition of a nuclear localization signal in the kinase central domainNucleocytoplasmic shuttling of JAZ, a new cargo protein for exportin-5.Protein kinase B phosphorylates AHNAK and regulates its subcellular localizationInsulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradationExpression of Drosophila FOXO regulates growth and can phenocopy starvationRedox regulation of FoxO transcription factorsCrystal structure of the human FOXO3a-DBD/DNA complex suggests the effects of post-translational modificationRegulation of sterol carrier protein gene expression by the forkhead transcription factor FOXO3aAn mRNA splice variant of the AFX gene with altered transcriptional activityThe hsp90 Co-chaperone XAP2 alters importin beta recognition of the bipartite nuclear localization signal of the Ah receptor and represses transcriptional activityFoxO6 transcriptional activity is regulated by Thr26 and Ser184, independent of nucleo-cytoplasmic shuttlingThe FoxO codeBoth the N-terminal loop and wing W2 of the forkhead domain of transcription factor Foxo4 are important for DNA bindingCharacterization of subpopulation lacking both B-cell and plasma cell markers in Waldenstrom macroglobulinemia cell lineGlucose induced MAPK signalling influences NeuroD1-mediated activation and nuclear localizationO-GlcNAcylation enhances FOXO4 transcriptional regulation in response to stressInsulin regulation of insulin-like growth factor-binding protein-1 gene expression is dependent on the mammalian target of rapamycin, but independent of ribosomal S6 kinase activitySERCA2a gene therapy restores microRNA-1 expression in heart failure via an Akt/FoxO3A-dependent pathwayA brief introduction to FOXOlogyTransport into and out of the nucleus.FOXO transcription factors at the interface between longevity and tumor suppressionFluorescence resonance energy transfer biosensors that detect Ran conformational changes and a Ran x GDP-importin-beta -RanBP1 complex in vitro and in intact cells.Substrate specificity of mammalian N-terminal α-amino methyltransferase NRMT14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transportFoxO transcription factors in oxidative stress response and ageing--a new fork on the way to longevity?Identification and analysis of evolutionary selection pressures acting at the molecular level in five forkhead subfamilies.Morphogenesis of Strongyloides stercoralis infective larvae requires the DAF-16 ortholog FKTF-1.14-3-3 protein masks the DNA binding interface of forkhead transcription factor FOXO4.Co-depletion of cathepsin B and uPAR induces G0/G1 arrest in glioma via FOXO3a mediated p27 upregulation.FOXOs, cancer and regulation of apoptosisZanthoxylum alkylamides ameliorate protein metabolism disorder in STZ-induced diabetic rats.The FoxO family in cardiac function and dysfunction.Spatio-temporal dynamics of protein kinase B/Akt signaling revealed by a genetically encoded fluorescent reporter.
P2860
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P2860
Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX.
description
2001 nî lūn-bûn
@nan
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Inhibition of nuclear import b ...... khead transcription factor AFX
@nl
Inhibition of nuclear import b ...... head transcription factor AFX.
@ast
Inhibition of nuclear import b ...... head transcription factor AFX.
@en
Inhibition of nuclear import b ...... head transcription factor AFX.
@en-gb
type
label
Inhibition of nuclear import b ...... khead transcription factor AFX
@nl
Inhibition of nuclear import b ...... head transcription factor AFX.
@ast
Inhibition of nuclear import b ...... head transcription factor AFX.
@en
Inhibition of nuclear import b ...... head transcription factor AFX.
@en-gb
prefLabel
Inhibition of nuclear import b ...... khead transcription factor AFX
@nl
Inhibition of nuclear import b ...... head transcription factor AFX.
@ast
Inhibition of nuclear import b ...... head transcription factor AFX.
@en
Inhibition of nuclear import b ...... head transcription factor AFX.
@en-gb
P2093
P2860
P3181
P1476
Inhibition of nuclear import b ...... khead transcription factor AFX
@en
P2093
A M Brownawell
B M Burgering
I G Macara
P2860
P304
P3181
P356
10.1128/MCB.21.10.3534-3546.2001
P407
P50
P577
2001-05-01T00:00:00Z