RPE65 is the isomerohydrolase in the retinoid visual cycle - Wikidata - thesis-toulmin - TriplyDB

RPE65 is the isomerohydrolase in the retinoid visual cycle

RPE65 is the isomerohydrolase in the retinoid visual cycle

http://www.wikidata.org/entity/Q24530226

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Retinal iron homeostasis in health and disease Lentiviral gene transfer of RPE65 rescues survival and function of cones in a mouse model of Leber congenital amaurosis Safety and efficacy of gene transfer for Leber's congenital amaurosis NinaB combines carotenoid oxygenase and retinoid isomerase activity in a single polypeptide Crystal structure of native RPE65, the retinoid isomerase of the visual cycle Role of LRAT on the retinoid isomerase activity and membrane association of Rpe65 Palmitoyl transferase activity of lecithin retinol acyl transferase How vision begins: an odyssey Clinical Trials in Retinal Dystrophies Recent advances in the dark adaptation investigations Structural basis of carotenoid cleavage: from bacteria to mammals Intracellular transport of fat-soluble vitamins A and E The many different cellular functions of MYO7A in the retina A comprehensive review of retinal gene therapy Importance of Membrane Structural Integrity for RPE65 Retinoid Isomerization Activity Human Cellular Retinaldehyde-Binding Protein Has Secondary Thermal 9- cis -Retinal Isomerase Activity Analysis of Carotenoid Isomerase Activity in a Prototypical Carotenoid Cleavage Enzyme, Apocarotenoid Oxygenase (ACO)Clinical applications of fundus autofluorescence in retinal disease Identification of key residues determining isomerohydrolase activity of human RPE65 Nonvisual light responses in the Rpe65 knockout mouse: rod loss restores sensitivity to the melanopsin system.Iron homeostasis and toxicity in retinal degeneration RPE65 is present in human green/red cones and promotes photopigment regeneration in an in vitro cone cell model Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial RPE65, visual cycle retinol isomerase, is not inherently 11-cis-specific: support for a carbocation mechanism of retinol isomerization Membrane-binding and enzymatic properties of RPE65 Safety and efficacy of subretinal readministration of a viral vector in large animals to treat congenital blindness Chemistry of the retinoid (visual) cycle Retinol dehydrogenase 13 protects the mouse retina from acute light damage A novel mutation in the RPE65 gene causing Leber congenital amaurosis and its transcriptional expression in vitro Alpha-phenyl-N-tert-butylnitrone (PBN) prevents light-induced degeneration of the retina by inhibiting RPE65 protein isomerohydrolase activity Localizations of visual cycle components in retinal pigment epithelium Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina RDH13L, an enzyme responsible for the aldehyde-alcohol redox coupling reaction (AL-OL coupling reaction) to supply 11-cis retinal in the carp cone retinoid cycle The Usher 1B protein, MYO7A, is required for normal localization and function of the visual retinoid cycle enzyme, RPE65 Origin and evolution of retinoid isomerization machinery in vertebrate visual cycle: hint from jawless vertebrates Pharmacological Amelioration of Cone Survival and Vision in a Mouse Model for Leber Congenital Amaurosis Chemistry and biology of the initial steps in vision: the Friedenwald lecture.Predicting the pathogenicity of RPE65 mutations.Comparative sequence analyses of rhodopsin and RPE65 reveal patterns of selective constraint across hereditary retinal disease mutations.PBN (Phenyl-N-Tert-Butylnitrone)-Derivatives Are Effective in Slowing the Visual Cycle and Rhodopsin Regeneration and in Protecting the Retina from Light-Induced Damage

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RPE65 is the isomerohydrolase in the retinoid visual cycle

http://www.wikidata.org/entity/Q24530226

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2005 nî lūn-bûn

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2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2005 թվականի օգոստոսին հրատարակված գիտական հոդված

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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name

RPE65 is the isomerohydrolase in the retinoid visual cycle

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RPE65 is the isomerohydrolase in the retinoid visual cycle

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RPE65 is the isomerohydrolase in the retinoid visual cycle

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type

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RPE65 is the isomerohydrolase in the retinoid visual cycle

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RPE65 is the isomerohydrolase in the retinoid visual cycle

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RPE65 is the isomerohydrolase in the retinoid visual cycle

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prefLabel

RPE65 is the isomerohydrolase in the retinoid visual cycle

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RPE65 is the isomerohydrolase in the retinoid visual cycle

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RPE65 is the isomerohydrolase in the retinoid visual cycle

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Proceedings of the National Academy of Sciences of the United States of America

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RPE65 is the isomerohydrolase in the retinoid visual cycle

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Bill X Wu

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Gennadiy Moiseyev

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Jian-Xing Ma

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Ying Chen

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Yusuke Takahashi

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P2860

Molecular and biochemical characterization of lecithin retinol acyltransferase

Cloning and characterization of a novel all-trans retinol short-chain dehydrogenase/reductase from the RPE

Mutations in RPE65 cause autosomal recessive childhood-onset severe retinal dystrophy

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Expression, purification, and MALDI analysis of RPE65

Rpe65 is a retinyl ester binding protein that presents insoluble substrate to the isomerase in retinal pigment epithelial cells

Characterization of a plasma retinol-binding protein membrane receptor expressed in the retinal pigment epithelium

The structure of a retinal-forming carotenoid oxygenase

Mutations in RPE65 cause Leber's congenital amaurosis

Molecular cloning and expression of RPE65, a novel retinal pigment epithelium-specific microsomal protein that is post-transcriptionally regulated in vitro

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35

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102

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16116091

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all-trans-retinyl ester

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