mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties
about
The interferon induced with helicase domain 1 A946T polymorphism is not associated with rheumatoid arthritisDown-regulation of Myc as a potential target for growth arrest induced by human polynucleotide phosphorylase (hPNPaseold-35) in human melanoma cellsRegulation of signal transduction by enzymatically inactive antiviral RNA helicase proteins MDA5, RIG-I, and LGP2Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus.MDA5 is SUMOylated by PIAS2β in the upregulation of type I interferon signalingA shared interface mediates paramyxovirus interference with antiviral RNA helicases MDA5 and LGP2Human polynucleotide phosphorylase selectively and preferentially degrades microRNA-221 in human melanoma cellsCardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virusRegulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2Innate immune recognition of viral infectionThe alpha/beta interferon response controls tissue tropism and pathogenicity of poliovirus.Dissociation of a MAVS/IPS-1/VISA/Cardif-IKKepsilon molecular complex from the mitochondrial outer membrane by hepatitis C virus NS3-4A proteolytic cleavageThe V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoterFunction and regulation of retinoic acid-inducible gene-IMDA-5 is cleaved in poliovirus-infected cellsImpact of protein kinase PKR in cell biology: from antiviral to antiproliferative actionNew Insights into the Biological Role of Mammalian ADARs; the RNA Editing ProteinsInterferon induction by RNA viruses and antagonism by viral pathogensMDA5 and LGP2: accomplices and antagonists of antiviral signal transductionTLR7/9 versus TLR3/MDA5 signaling during virus infections and diabetesRole of RNA helicases in HIV-1 replicationPathogenesis of West Nile Virus Infection: a Balance between Virulence, Innate and Adaptive Immunity, and Viral EvasionClassical Swine Fever Virus Npro Interacts with Interferon Regulatory Factor 3 and Induces Its Proteasomal DegradationWest Nile Virus-Induced Interferon Production Is Mediated by the Double-Stranded RNA-Dependent Protein Kinase PKRBoth RIG-I and MDA5 RNA Helicases Contribute to the Induction of Alpha/Beta Interferon in Measles Virus-Infected Human CellsMelanoma Differentiation-Associated Gene 5 (MDA5) Is Involved in the Innate Immune Response to Paramyxoviridae Infection In VivoIPS-1 Is Essential for the Control of West Nile Virus Infection and ImmunityThe RIG-I ATPase domain structure reveals insights into ATP-dependent antiviral signallingMDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNAThe RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responsesEpstein-Barr virus latent genesNF-kappaB and the immune responseRNA-based mechanisms regulating host-virus interactionsTLR signalingInnate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasomeAEG-1/MTDH/LYRIC, the beginning: initial cloning, structure, expression profile, and regulation of expressionConvergent evolution of escape from hepaciviral antagonism in primatesInduction of type I interferon by RNA viruses: cellular receptors and their substratesEssential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirusExpression analysis and genomic characterization of human melanoma differentiation associated gene-5, mda-5: a novel type I interferon-responsive apoptosis-inducing gene.
P2860
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P2860
mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties
description
2002 nî lūn-bûn
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2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2002 թվականի հունվարին հրատարակված գիտական հոդված
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2002年の論文
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2002年学术文章
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name
mda-5: An interferon-inducible ...... growth-suppressive properties
@ast
mda-5: An interferon-inducible ...... growth-suppressive properties
@en
mda-5: An interferon-inducible ...... growth-suppressive properties
@nl
type
label
mda-5: An interferon-inducible ...... growth-suppressive properties
@ast
mda-5: An interferon-inducible ...... growth-suppressive properties
@en
mda-5: An interferon-inducible ...... growth-suppressive properties
@nl
prefLabel
mda-5: An interferon-inducible ...... growth-suppressive properties
@ast
mda-5: An interferon-inducible ...... growth-suppressive properties
@en
mda-5: An interferon-inducible ...... growth-suppressive properties
@nl
P2093
P2860
P3181
P356
P1476
mda-5: An interferon-inducible ...... growth-suppressive properties
@en
P2093
Anna Marie Pyle
Dong-chul Kang
Paul B Fisher
Qingping Wu
Rahul V Gopalkrishnan
P2860
P304
P3181
P356
10.1073/PNAS.022637199
P407
P577
2002-01-22T00:00:00Z