The reaction of mono- and di-functional alkylating agents with nucleic acids
about
A Bridging Water Anchors the Tethered 5-(3-Aminopropyl)-2′-deoxyuridine Amine in the DNA Major Groove Proximate to the N+2 C·G Base Pair: Implications for Formation of Interstrand 5′-GNC-3′ Cross-Links by Nitrogen Mustards † , ‡Toxicity of vesicant agents scheduled for destruction by the Chemical Stockpile Disposal ProgramAlkylation by propylene oxide of deoxyribonucleic acid, adenine, guanosine and deoxyguanylic acidAlkylation by 1,2:5,6-dianhydrogalactitol of deoxyribonucleic acid and guanosineRe-directing an alkylating agent to mitochondria alters drug target and cell death mechanismInduction by alkylating agents of sister chromatid exchanges and chromatid breaks in Fanconi's anemiaDNA interstrand cross-linking activity of (1-Chloroethenyl)oxirane, a metabolite of beta-chloroprene.A structural basis for a phosphoramide mustard-induced DNA interstrand cross-link at 5'-d(GAC)7-Methylguanine adducts in DNA are normally present at high levels and increase on aging: analysis by HPLC with electrochemical detectionThe sources, fate, and toxicity of chemical warfare agent degradation products.Forward and reverse mutagenesis in C. elegans.Interactions of sulfur-containing acridine ligands with DNA by ESI-MS.Reactive oxygen species (ROS) inducible DNA cross-linking agents and their effect on cancer cells and normal lymphocytes.Chemical probes for higher-order structure in RNA.Using synthetic DNA interstrand crosslinks to elucidate repair pathways and identify new therapeutic targets for cancer chemotherapy.Therapy-related leukemia associated with alkylating agents.ALTERATIONS IN CELLULAR METABOLISM ASSOCIATED WITH CELL DEATH INDUCED BY URACIL MUSTARD AND 6-THIOGUANINE.Cross-linking and repair of DNA in sensitive and resistant strains of E. coli treated with nitrogen mustard.O6 alkylguanine-DNA alkyltransferase activity in human myeloid cells.The formation and biological significance of N7-guanine adductsGenetic and biochemical characterization of waxy mutants in cerealsThe 5'-GNC site for DNA interstrand cross-linking is conserved for diepoxybutane stereoisomersRepair of DNA containing interstrand crosslinks in Escherichia coli: sequential excision and recombination.Unscheduled DNA synthesis in the germ cells of male mice exposed in vivo to the chemical mutagen ethyl methanesulfonate.Diepoxybutane interstrand cross-links induce DNA bending.Hydrogen peroxide inducible DNA cross-linking agents: targeted anticancer prodrugs.Noncovalent DNA binding drives DNA alkylation by leinamycin: evidence that the Z,E-5-(thiazol-4-yl)-penta-2,4-dienone moiety of the natural product serves as an atypical DNA intercalator.Carcinogenicity of alkylating agents.Inhibition of NADPH cytochrome P450 reductase by the model sulfur mustard vesicant 2-chloroethyl ethyl sulfide is associated with increased production of reactive oxygen species.Characterization of nitrogen mustard formamidopyrimidine adduct formation of bis(2-chloroethyl)ethylamine with calf thymus DNA and a human mammary cancer cell lineMechanisms of DNA sequence selective alkylation of guanine-N7 positions by nitrogen mustards.The pharmacology, toxicology, and medical treatment of sulphur mustard poisoning.A method for the isolation of cross-linked nucleosides from DNA: application to cross-links induced by nitrous acid.SYNERGISTIC ACTION OF NITROGEN MUSTARD AND RADIATION IN MICROORGANISMS.Fanconi-like crosslink repair in yeast.Role of gene 59 of bacteriophage T4 in repair of UV-irradiated and alkylated DNA in vivo.A review of the role of the sequence-dependent electrostatic landscape in DNA alkylation patterns.Photoinitiated release of an aziridinium ion precursor for the temporally controlled alkylation of nucleophilesRepair of alkylation damage: stability of methyl groups in Bacillus subtilis treated with methyl methanesulfonate.Mechanisms of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced DNA damage in skin epidermal cells and fibroblasts
P2860
Q27650806-4486945D-7F4C-42BC-B862-B41704F87905Q28318137-CF2552AF-6E6D-483D-A0B0-EC152E853212Q28364563-B936D0EC-FA1A-4B42-BECC-75A5F5F9EF55Q28367108-746ADAE5-5EF2-4EFA-BE1F-64CBCAC2A15AQ28486104-D8E81DBF-7C56-4D15-B88D-B653B7CAFF42Q33179314-85CEEB35-81CF-4C4E-BCBB-C275D690CEB2Q33622251-E5299390-64D3-4618-B5D7-79CB0FC86FF5Q33653106-E312DBC6-ADF1-4B4C-AECD-F066E747C397Q33653917-A51A1821-7311-46B5-862D-4875EC9039AEQ33787029-840ACBEE-0CB1-4BE2-9B7D-AB3EFEABD3B4Q33834330-8330FFDE-77A5-4E74-927C-ED1DDB47B4C8Q33944009-B33639A5-BB2E-40A0-94E6-E7330B6E44F7Q34049655-E76F3F35-9287-4049-9C2D-989156C196E7Q34054857-AB924BC5-003F-4644-867D-1656A39AEE97Q34132691-401BE388-9CAF-4094-9058-AF6CC71C0D41Q34243510-7B5F1C5D-250A-45C2-8015-ADA8CF7BF280Q34417897-E57E8C50-A30E-425D-BFD9-714600E123D6Q34456938-7504BAC1-22BD-4D85-93CB-FE3C8124CFAAQ34568108-B26840F2-A7D8-4CD4-AA11-7AA8F92A7929Q34982742-17A38224-FEA6-4DCA-B47B-1524A9062461Q35035674-0C8137FB-26F8-4061-B480-4204E1423E03Q35080222-51784216-DF9A-4AA7-B5FA-5D1848875E07Q35100710-CFF396CB-11CA-4B1C-8954-52AFA1DE2003Q35120558-4F08EE62-D8A0-431D-98ED-65360CE4AD27Q35608561-989D4E88-3201-4A4F-A2D7-593F0E32E542Q35694142-37DCD4C7-FE6A-4153-80FB-0B1953A61DB3Q35707736-01AE427D-152F-469D-AC7F-D85F64BDBC5DQ35892826-B19B94FD-1EE4-437A-ABF4-034F5E7EA0DEQ35967421-E50016FA-900B-49A1-A1D4-38AED56BA7C0Q36083594-5F44A683-8BC2-4AE5-AD65-ABB2D825C479Q36102691-C4DDB49D-D6A3-4984-9A85-BB398D86D0B3Q36135593-02F589BC-12EC-4F41-B9A9-05960876C5E4Q36181951-15E9B2D9-45F3-491B-93B1-6A94F05C4E37Q36415980-AF73557E-10E2-4E50-8403-420DF6ADDDEEQ36473087-AD300285-2434-4E31-8FF7-216F3251EF46Q36536926-754FF1D9-A9FD-4E46-AA68-291682F13118Q36656400-3130DDC7-E1CF-40C9-BEE4-47B9F7BDD7D5Q36718975-49DA9CAA-BBAD-448D-9D2D-737198FBE997Q36779290-174A4C42-0C66-4398-8C0E-A41A0663DE17Q36870709-AA974B3E-7616-4E34-AF20-89D8D6641B40
P2860
The reaction of mono- and di-functional alkylating agents with nucleic acids
description
1961 nî lūn-bûn
@nan
1961 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1961 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1961年の論文
@ja
1961年論文
@yue
1961年論文
@zh-hant
1961年論文
@zh-hk
1961年論文
@zh-mo
1961年論文
@zh-tw
1961年论文
@wuu
name
The reaction of mono- and di-functional alkylating agents with nucleic acids
@ast
The reaction of mono- and di-functional alkylating agents with nucleic acids
@en
The reaction of mono- and di-functional alkylating agents with nucleic acids
@en-gb
The reaction of mono- and di-functional alkylating agents with nucleic acids
@nl
type
label
The reaction of mono- and di-functional alkylating agents with nucleic acids
@ast
The reaction of mono- and di-functional alkylating agents with nucleic acids
@en
The reaction of mono- and di-functional alkylating agents with nucleic acids
@en-gb
The reaction of mono- and di-functional alkylating agents with nucleic acids
@nl
prefLabel
The reaction of mono- and di-functional alkylating agents with nucleic acids
@ast
The reaction of mono- and di-functional alkylating agents with nucleic acids
@en
The reaction of mono- and di-functional alkylating agents with nucleic acids
@en-gb
The reaction of mono- and di-functional alkylating agents with nucleic acids
@nl
P3181
P356
P1433
P1476
The reaction of mono- and di-functional alkylating agents with nucleic acids
@en
P2093
P2860
P304
P3181
P356
10.1042/BJ0800496
P407
P577
1961-09-01T00:00:00Z