Characterization of the Aalpha and Abeta subunit isoforms of protein phosphatase 2A: differences in expression, subunit interaction, and evolution
about
The tumor suppressor PP2A Abeta regulates the RalA GTPasePP2A: more than a reset switch to activate pRB proteins during the cell cycle and in response to signaling cues.Structural and biochemical characterization of human PR70 in isolation and in complex with the scaffolding subunit of protein phosphatase 2AThe Basic Biology of PP2A in Hematologic Cells and MalignanciesPP2A: The Wolf in Sheep's Clothing?Specificity of RCN1-mediated protein phosphatase 2A regulation in meristem organization and stress response in roots.Phosphorylated protein phosphatase 2A determines poor outcome in patients with metastatic colorectal cancer.Phosphatase: PP2A structural importance, regulation and its aberrant expression in cancer.Cellular transformation by Simian Virus 40 and Murine Polyoma Virus T antigens.Lessons in signaling and tumorigenesis from polyomavirus middle T antigen.The role of serine/threonine protein phosphatases in exocytosisHuman cancer-associated mutations in the Aα subunit of protein phosphatase 2A increase lung cancer incidence in Aα knock-in and knockout mice.Mouse model for probing tumor suppressor activity of protein phosphatase 2A in diverse signaling pathways.Protein phosphatase 2A subunit PR70 interacts with pRb and mediates its dephosphorylationMolecular mechanisms underlying cardiac protein phosphatase 2A regulation in heart.Effects of phosphatase and proteasome inhibitors on Borealin phosphorylation and degradationProtein phosphatase 2A isoforms utilizing Aβ scaffolds regulate differentiation through control of Akt protein.Lessons from polyoma middle T antigen on signaling and transformation: A DNA tumor virus contribution to the war on cancer.The role of PP2A A subunits in tumor suppressionRole for PP2A in ARF signaling to p53.Comparisons between murine polyomavirus and Simian virus 40 show significant differences in small T antigen function.Quantitative proteomics reveals novel protein interaction partners of PP2A catalytic subunit in pancreatic β-cellsProtein phosphatase 2A is essential to maintain active Wnt signaling and its Aβ tumor suppressor subunit is not expressed in colon cancer cells.Protein phosphatase 2A dephosphorylates phosphoserines in nucleocytoplasmic shuttling and secretion of high mobility group box 1.Protein Phosphatase 2A: a Double-Faced Phosphatase of Cellular System and Its Role in Neurodegenerative Disorders.Protein phosphatase 4 regulates apoptosis in leukemic and primary human T-cells.Polymerized collagen inhibits fibroblast proliferation via a mechanism involving the formation of a beta1 integrin-protein phosphatase 2A-tuberous sclerosis complex 2 complex that suppresses S6K1 activity.Dephosphorylation of JC virus agnoprotein by protein phosphatase 2A: inhibition by small t antigen.The formation and activity of PP2A holoenzymes do not depend on the isoform of the catalytic subunit.Subtype-specific mutation of PPP2R1A in endometrial and ovarian carcinomas.The tumor suppressor phosphatase PP2A-B56α regulates stemness and promotes the initiation of malignancies in a novel murine model.Disparate roles for the regulatory A subunit isoforms in Arabidopsis protein phosphatase 2A.Functional importance of PP2A regulatory subunit loss in breast cancer.PP2A impaired activity is a common event in acute myeloid leukemia and its activation by forskolin has a potent anti-leukemic effect.Phosphatase Type 2A-dependent and -independent Pathways for ATR Phosphorylation of Chk1
P2860
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P2860
Characterization of the Aalpha and Abeta subunit isoforms of protein phosphatase 2A: differences in expression, subunit interaction, and evolution
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Characterization of the Aalpha ...... nit interaction, and evolution
@ast
Characterization of the Aalpha ...... nit interaction, and evolution
@en
Characterization of the Aalpha ...... nit interaction, and evolution
@en-gb
Characterization of the Aalpha ...... nit interaction, and evolution
@nl
type
label
Characterization of the Aalpha ...... nit interaction, and evolution
@ast
Characterization of the Aalpha ...... nit interaction, and evolution
@en
Characterization of the Aalpha ...... nit interaction, and evolution
@en-gb
Characterization of the Aalpha ...... nit interaction, and evolution
@nl
prefLabel
Characterization of the Aalpha ...... nit interaction, and evolution
@ast
Characterization of the Aalpha ...... nit interaction, and evolution
@en
Characterization of the Aalpha ...... nit interaction, and evolution
@en-gb
Characterization of the Aalpha ...... nit interaction, and evolution
@nl
P2093
P2860
P356
P1433
P1476
Characterization of the Aalpha ...... nit interaction, and evolution
@en
P2093
Gernot Walter
Huong T Pham
Ralf Ruediger
P2860
P304
P356
10.1042/BJ20021244
P407
P577
2003-01-15T00:00:00Z