Repacking of the transmembrane domains of P-glycoprotein during the transport ATPase cycle - Wikidata - thesis-toulmin - TriplyDB

Repacking of the transmembrane domains of P-glycoprotein during the transport ATPase cycle

Repacking of the transmembrane domains of P-glycoprotein during the transport ATPase cycle

http://www.wikidata.org/entity/Q24535845

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Conformational motion of the ABC transporter MsbA induced by ATP hydrolysis ABC transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversal Apatinib (YN968D1) reverses multidrug resistance by inhibiting the efflux function of multiple ATP-binding cassette transporters Flexibility in the ABC transporter MsbA: Alternating access with a twist.ABC transporter research: going strong 40 years on Providing a molecular mechanism for P-glycoprotein; why would I bother?Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states Vandetanib (Zactima, ZD6474) antagonizes ABCC1- and ABCG2-mediated multidrug resistance by inhibition of their transport function NSC23925, identified in a high-throughput cell-based screen, reverses multidrug resistance Structural and functional asymmetry of the nucleotide-binding domains of P-glycoprotein investigated by attenuated total reflection Fourier transform infrared spectroscopy Molecular modelling of drug targets: the past, the present and the future.Xenobiotic, bile acid, and cholesterol transporters: function and regulation.Diversity and versatility of lipid-protein interactions revealed by molecular genetic approaches.Drug resistance in brain diseases and the role of drug efflux transporters.Vanadate trapping of nucleotide at the ATP-binding sites of human multidrug resistance P-glycoprotein exposes different residues to the drug-binding site How are the ABC transporters energized?Intermediate structural states involved in MRP1-mediated drug transport. Role of glutathione.Nucleotide-dependent conformational changes in HisP: molecular dynamics simulations of an ABC transporter nucleotide-binding domain.Topology of polytopic membrane protein subdomains is dictated by membrane phospholipid composition Regulation of bacterial drug export systems Identification, mutagenesis, and transcriptional analysis of the methanesulfonate transport operon of Methylosulfonomonas methylovora.Vibrio cholerae strains with mutations in an atypical type I secretion system accumulate RTX toxin intracellularly Dynamics of alpha-helical subdomain rotation in the intact maltose ATP-binding cassette transporter Functional hot spots in human ATP-binding cassette transporter nucleotide binding domains.A mechanistic approach to understanding the factors affecting drug absorption: a review of fundamentals.Mystery of multidrug transporters: the answer can be simple.P-glycoprotein retains drug-stimulated ATPase activity upon covalent linkage of the two nucleotide binding domains at their C-terminal ends.Structure and function of efflux pumps that confer resistance to drugs Structural basis for the channel function of a degraded ABC transporter, CFTR (ABCC7).The engine of ABC proteins.ABC transporter architecture and mechanism: implications from the crystal structures of BtuCD and BtuF.How do ABC transporters drive transport?The ATPase activity of the P-glycoprotein drug pump is highly activated when the N-terminal and central regions of the nucleotide-binding domains are linked closely together The translocation mechanism of P-glycoprotein.Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins.ZD6474 reverses multidrug resistance by directly inhibiting the function of P-glycoprotein.Molecular disruption of the power stroke in the ATP-binding cassette transport protein MsbA.Structure and function of ABC transporters.A single active catalytic site is sufficient to promote transport in P-glycoprotein Uptake or extrusion: crystal structures of full ABC transporters suggest a common mechanism.

P2860

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P2860

Repacking of the transmembrane domains of P-glycoprotein during the transport ATPase cycle

http://www.wikidata.org/entity/Q24535845

description

2001 nî lūn-bûn

@nan

2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年论文

@wuu

name

Repacking of the transmembrane ...... ing the transport ATPase cycle

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Repacking of the transmembrane ...... ing the transport ATPase cycle

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Repacking of the transmembrane ...... ing the transport ATPase cycle

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type

label

Repacking of the transmembrane ...... ing the transport ATPase cycle

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Repacking of the transmembrane ...... ing the transport ATPase cycle

@en

Repacking of the transmembrane ...... ing the transport ATPase cycle

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prefLabel

Repacking of the transmembrane ...... ing the transport ATPase cycle

@ast

Repacking of the transmembrane ...... ing the transport ATPase cycle

@en

Repacking of the transmembrane ...... ing the transport ATPase cycle

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P3181

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P1433

The EMBO Journal

P1476

Repacking of the transmembrane ...... ing the transport ATPase cycle

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P2093

A Schmidlin

http://www.w3.org/2001/XMLSchema#string

C F Higgins

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C Martin

http://www.w3.org/2001/XMLSchema#string

C Wooding

http://www.w3.org/2001/XMLSchema#string

G Berridge

http://www.w3.org/2001/XMLSchema#string

G Velarde

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K J Linton

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M F Rosenberg

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P2860

Spectroscopic mapping of voltage sensor movement in the Shaker potassium channel

Atomic scale movement of the voltage-sensing region in a potassium channel measured via spectroscopy

Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6 A resolution

The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel

Crystal structure of the ATP-binding subunit of an ABC transporter

The CCP4 suite: programs for protein crystallography

ABC transporters: from microorganisms to man

A bacterial antibiotic-resistance gene that complements the human multidrug-resistance P-glycoprotein gene

Cryo-electron microscopy of vitrified specimens

Areas, volumes, packing and protein structure

P304

5615-5625

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scholarly article

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2061492

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P356

10.1093/EMBOJ/20.20.5615

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P407

P433

20

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P478

20

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P50

Richard Callaghan

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2001-10-01T00:00:00Z

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11752143

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11598005

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P921

transmembrane transport

transmembrane protein

P932

125677

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