Distinctive modulatory effects of five human auxiliary beta2 subunit splice variants on L-type calcium channel gating.
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Orientation of the calcium channel beta relative to the alpha(1)2.2 subunit is critical for its regulation of channel activityL-type calcium channel targeting and local signalling in cardiac myocytesIon channel remodeling in vascular smooth muscle during hypertension: Implications for novel therapeutic approachesThe Ca2+ channel subunit beta2 regulates Ca2+ channel abundance and function in inner hair cells and is required for hearingThe ß subunit of voltage-gated Ca2+ channelsFunctional dissection of the intramolecular Src homology 3-guanylate kinase domain coupling in voltage-gated Ca2+ channel beta-subunits.The calcium channel beta2 (CACNB2) subunit repertoire in teleosts.Functional modularity of the beta-subunit of voltage-gated Ca2+ channels.A CaVbeta SH3/guanylate kinase domain interaction regulates multiple properties of voltage-gated Ca2+ channels.Membrane-associated guanylate kinase-like properties of beta-subunits required for modulation of voltage-dependent Ca2+ channelsThe N-terminal domain tethers the voltage-gated calcium channel β2e-subunit to the plasma membrane via electrostatic and hydrophobic interactionsOrientation of palmitoylated CaVbeta2a relative to CaV2.2 is critical for slow pathway modulation of N-type Ca2+ current by tachykinin receptor activation.Atypical properties of a conventional calcium channel beta subunit from the platyhelminth Schistosoma mansoni.Negatively charged residues in the N-terminal of the AID helix confer slow voltage dependent inactivation gating to CaV1.2.Transcript scanning reveals novel and extensive splice variations in human l-type voltage-gated calcium channel, Cav1.2 alpha1 subunit.Increased expression of the auxiliary beta(2)-subunit of ventricular L-type Ca(2)+ channels leads to single-channel activity characteristic of heart failureEffect of Ca(v)beta subunits on structural organization of Ca(v)1.2 calcium channels.Diversity and developmental expression of L-type calcium channel beta2 proteins and their influence on calcium current in murine heart.Allethrin differentially modulates voltage-gated calcium channel subtypes in rat PC12 cells.Voltage-gated rearrangements associated with differential beta-subunit modulation of the L-type Ca(2+) channel inactivationNon-voltage-gated L-type Ca2+ channels in human T cells: pharmacology and molecular characterization of the major alpha pore-forming and auxiliary beta-subunits.Bio-inspired voltage-dependent calcium channel blockersModerate calcium channel dysfunction in adult mice with inducible cardiomyocyte-specific excision of the cacnb2 gene.Rare mutations of CACNB2 found in autism spectrum disease-affected families alter calcium channel function.Dynamic phospholipid interaction of β2e subunit regulates the gating of voltage-gated Ca2+ channels.Molecular Basis of the Membrane Interaction of the β2e Subunit of Voltage-Gated Ca(2+) Channels.A novel Ca(V)1.2 N terminus expressed in smooth muscle cells of resistance size arteries modifies channel regulation by auxiliary subunits.Arrhythmogenesis in Timothy Syndrome is associated with defects in Ca(2+)-dependent inactivationGenomic organization, expression, and phylogenetic analysis of Ca2+ channel beta4 genes in 13 vertebrate species.Cooperative regulation of Ca(v)1.2 channels by intracellular Mg(2+), the proximal C-terminal EF-hand, and the distal C-terminal domain.Reverse engineering the L-type Ca2+ channel alpha1c subunit in adult cardiac myocytes using novel adenoviral vectorsRegulation of voltage-gated Ca2+ channels by lipids.Engineering proteins for custom inhibition of Ca(V) channels.Trafficking and stability of voltage-gated calcium channels.Structure and function of the β subunit of voltage-gated Ca²⁺ channels.Regulation of voltage-dependent calcium channels by RGK proteins.L-type Ca2+ channels in heart and brainTransmural gradients in ion channel and auxiliary subunit expression.The HOOK region of voltage-gated Ca2+ channel β subunits senses and transmits PIP2 signals to the gate.Localization and mobility of the delayed-rectifer K+ channel Kv2.1 in adult cardiomyocytes.
P2860
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P2860
Distinctive modulatory effects of five human auxiliary beta2 subunit splice variants on L-type calcium channel gating.
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Distinctive modulatory effects ...... L-type calcium channel gating
@nl
Distinctive modulatory effects ...... L-type calcium channel gating.
@ast
Distinctive modulatory effects ...... L-type calcium channel gating.
@en
Distinctive modulatory effects ...... L-type calcium channel gating.
@en-gb
type
label
Distinctive modulatory effects ...... L-type calcium channel gating
@nl
Distinctive modulatory effects ...... L-type calcium channel gating.
@ast
Distinctive modulatory effects ...... L-type calcium channel gating.
@en
Distinctive modulatory effects ...... L-type calcium channel gating.
@en-gb
prefLabel
Distinctive modulatory effects ...... L-type calcium channel gating
@nl
Distinctive modulatory effects ...... L-type calcium channel gating.
@ast
Distinctive modulatory effects ...... L-type calcium channel gating.
@en
Distinctive modulatory effects ...... L-type calcium channel gating.
@en-gb
P2093
P2860
P1433
P1476
Distinctive modulatory effects ...... L-type calcium channel gating.
@en
P2093
Henry M Colecraft
Scott Mittman
Shoji X Takahashi
P2860
P304
P356
10.1016/S0006-3495(03)70027-7
P407
P577
2003-05-01T00:00:00Z