HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim.
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HIV-1 Tat protein enhances microtubule polymerizationThe C Terminus of HIV-1 Tat Modulates the Extent of CD178-mediated Apoptosis of T CellsThe Glutamine-rich Region of the HIV-1 Tat Protein Is Involved in T-cell ApoptosisPACAP27 is protective against tat-induced neurotoxicityHIV-1 Tat, apoptosis and the mitochondria: a tubulin link?HIV-1 Tat enters T cells using coated pits before translocating from acidified endosomes and eliciting biological responsesMitochondrial DNA haplogroups influence AIDS progressionHIV-1 Tat interacts with LIS1 proteinThe cross-talk of HIV-1 Tat and methamphetamine in HIV-associated neurocognitive disordersHuman immunodeficiency virus (HIV)-1 proteins and cytoskeleton: partners in viral life and host cell deathHIV-1 Tat protein directly induces mitochondrial membrane permeabilization and inactivates cytochrome c oxidaseViral control of mitochondrial apoptosisA versatile viral system for expression and depletion of proteins in mammalian cellsA comparative analysis of mitochondrial ORFans: new clues on their origin and role in species with doubly uniparental inheritance of mitochondriaAcetylated Tat regulates human immunodeficiency virus type 1 splicing through its interaction with the splicing regulator p32.Recruitment and activation of RSK2 by HIV-1 TatThe HIV Tat protein affects processing of ribosomal RNA precursor.HIV-1 Tat regulates cyclin B1 by promoting both expression and degradationAssociation of Tat with promoters of PTEN and PP2A subunits is key to transcriptional activation of apoptotic pathways in HIV-infected CD4+ T cells.Modifications in host cell cytoskeleton structure and function mediated by intracellular HIV-1 Tat protein are greatly dependent on the second coding exonThe association of viral proteins with host cell dynein components during virus infection.Exposure to the viral by-product dsRNA or Coxsackievirus B5 triggers pancreatic beta cell apoptosis via a Bim / Mcl-1 imbalance.The HIV-1 transactivator factor (Tat) induces enterocyte apoptosis through a redox-mediated mechanismThe ins and outs of HIV-1 Tat.Modulation of the stability and activities of HIV-1 Tat by its ubiquitination and carboxyl-terminal regionReservoir cells no longer detectable after a heterologous SHIV challenge with the synthetic HIV-1 Tat Oyi vaccine.Mechanisms of HIV-associated lymphocyte apoptosis: 2010Human immunodeficiency virus-1 (HIV-1)-mediated apoptosis: new therapeutic targets.Regulation of Tat acetylation and transactivation activity by the microtubule-associated deacetylase HDAC6.Genome-wide analysis of primary CD4+ and CD8+ T cell transcriptomes shows evidence for a network of enriched pathways associated with HIV disease.Systematic Analysis of the Functions of Lysine Acetylation in the Regulation of Tat ActivityViral-host interactions that control HIV-1 transcriptional elongationInhibition of PP2A by LIS1 increases HIV-1 gene expression.Neurodegenerative effects of recombinant HIV-1 Tat(1-86) are associated with inhibition of microtubule formation and oxidative stress-related reductions in microtubule-associated protein-2(a,b)The strength of the HIV-1 3' splice sites affects Rev function.Distinct structural domains within C19ORF5 support association with stabilized microtubules and mitochondrial aggregation and genome destructionT-cell and neuronal apoptosis in HIV infection: implications for therapeutic intervention.Determining confidence of predicted interactions between HIV-1 and human proteins using conformal method.Drosophila as a genetic model for studying pathogenic human virusesCaspase cleavage of BimEL triggers a positive feedback amplification of apoptotic signaling.
P2860
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P2860
HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim.
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
HIV-1 Tat targets microtubules ...... o-apoptotic Bcl-2 relative Bim
@nl
HIV-1 Tat targets microtubules ...... -apoptotic Bcl-2 relative Bim.
@ast
HIV-1 Tat targets microtubules ...... -apoptotic Bcl-2 relative Bim.
@en
type
label
HIV-1 Tat targets microtubules ...... o-apoptotic Bcl-2 relative Bim
@nl
HIV-1 Tat targets microtubules ...... -apoptotic Bcl-2 relative Bim.
@ast
HIV-1 Tat targets microtubules ...... -apoptotic Bcl-2 relative Bim.
@en
prefLabel
HIV-1 Tat targets microtubules ...... o-apoptotic Bcl-2 relative Bim
@nl
HIV-1 Tat targets microtubules ...... -apoptotic Bcl-2 relative Bim.
@ast
HIV-1 Tat targets microtubules ...... -apoptotic Bcl-2 relative Bim.
@en
P2093
P2860
P3181
P356
P1433
P1476
HIV-1 Tat targets microtubules ...... -apoptotic Bcl-2 relative Bim.
@en
P2093
Michael Wang
Qiang Zhou
Sharleen Zhou
P2860
P304
P3181
P356
10.1093/EMBOJ/CDF683
P407
P577
2002-12-01T00:00:00Z