Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN
about
Podocin localizes in the kidney to the slit diaphragm areaMotor protein Myo1c is a podocyte protein that facilitates the transport of slit diaphragm protein Neph1 to the podocyte membraneNck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytesFunctional and spatial analysis of C. elegans SYG-1 and SYG-2, orthologs of the Neph/nephrin cell adhesion module directing selective synaptogenesisG-protein coupled receptor BAI3 promotes myoblast fusion in vertebrates.Genotype-phenotype correlations in non-Finnish congenital nephrotic syndromeIschemic injury to kidney induces glomerular podocyte effacement and dissociation of slit diaphragm proteins Neph1 and ZO-1Neph1 and nephrin interaction in the slit diaphragm is an important determinant of glomerular permeabilityAlpha-actinin-4-mediated FSGS: an inherited kidney disease caused by an aggregated and rapidly degraded cytoskeletal proteinDrosophila tools and assays for the study of human diseasesPodocytesRole of Neuropilin-1 in Diabetic NephropathyRoles of adaptor proteins in podocyte biologyGenes and podocytes - new insights into mechanisms of podocytopathyThe adaptor protein Grb2 is not essential for the establishment of the glomerular filtration barrierSolution structure analysis of cytoplasmic domain of podocyte protein Neph1 using small/wide angle x-ray scattering (SWAXS)The carboxyl terminus of Neph family members binds to the PDZ domain protein zonula occludens-1Lipid-lowering effects of anti-angiopoietin-like 4 antibody recapitulate the lipid phenotype found in angiopoietin-like 4 knockout miceUpdate on the glomerular filtration barrierCharacterization of PTPRG in knockdown and phosphatase-inactive mutant mice and substrate trapping analysis of PTPRG in mammalian cellsTargeted disruption of leucine-rich repeat kinase 1 but not leucine-rich repeat kinase 2 in mice causes severe osteopetrosisTrans-interaction of nephrin and Neph1/Neph3 induces cell adhesion that associates with decreased tyrosine phosphorylation of nephrinA model organism approach: defining the role of Neph proteins as regulators of neuron and kidney morphogenesisCell junction-associated proteins IQGAP1, MAGI-2, CASK, spectrins, and alpha-actinin are components of the nephrin multiprotein complexSlit diaphragms contain tight junction proteinsNephrin and Neph1 co-localize at the podocyte foot process intercellular junction and form cis hetero-oligomersThe intellectual disability gene Kirrel3 regulates target-specific mossy fiber synapse development in the hippocampusPTH stimulates bone formation in mice deficient in Lrp5Neph1 cooperates with nephrin to transduce a signal that induces actin polymerizationNephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization.Comparative analysis of Neph gene expression in mouse and chicken developmentPolychaetoid controls patterning by modulating adhesion in the Drosophila pupal retinaSns and Kirre, the Drosophila orthologs of Nephrin and Neph1, direct adhesion, fusion and formation of a slit diaphragm-like structure in insect nephrocytes.Podocyte glutamatergic signaling contributes to the function of the glomerular filtration barrier.The glomerular transcriptome and a predicted protein-protein interaction network.Renal thrombotic microangiopathy in mice with combined deletion of endocytic recycling regulators EHD3 and EHD4.Identification of proteins that interact with podocin using the yeast 2-hybrid system.Regulation of Neph3 gene in podocytes--key roles of transcription factors NF-kappaB and Sp1.Beneficial effects of the Rho kinase inhibitor Y27632 in murine puromycin aminonucleoside nephrosisPodocyte-specific overexpression of wild type or mutant trpc6 in mice is sufficient to cause glomerular disease.
P2860
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P2860
Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN
description
2001 nî lūn-bûn
@nan
2001 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Proteinuria and perinatal leth ...... otein with homology to NEPHRIN
@ast
Proteinuria and perinatal leth ...... otein with homology to NEPHRIN
@en
Proteinuria and perinatal leth ...... otein with homology to NEPHRIN
@nl
type
label
Proteinuria and perinatal leth ...... otein with homology to NEPHRIN
@ast
Proteinuria and perinatal leth ...... otein with homology to NEPHRIN
@en
Proteinuria and perinatal leth ...... otein with homology to NEPHRIN
@nl
prefLabel
Proteinuria and perinatal leth ...... otein with homology to NEPHRIN
@ast
Proteinuria and perinatal leth ...... otein with homology to NEPHRIN
@en
Proteinuria and perinatal leth ...... otein with homology to NEPHRIN
@nl
P2093
P2860
P3181
P1476
Proteinuria and perinatal leth ...... otein with homology to NEPHRIN
@en
P2093
B N Mathur
B P Zambrowicz
C A Montgomery
C A Turner
D B Donoviel
D G Potter
D R Powell
P2860
P304
P3181
P356
10.1128/MCB.21.14.4829-4836.2001
P407
P577
2001-07-01T00:00:00Z