Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1 - Wikidata - thesis-toulmin - TriplyDB

Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1

Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1

http://www.wikidata.org/entity/Q24551095

about

A quality control mechanism linking meiotic success to release of ascospores Identification and characterization of human MUS81-MMS4 structure-specific endonuclease Human MUS81 complexes stimulate flap endonuclease 1 Holliday junction resolution in human cells: two junction endonucleases with distinct substrate specificities Haploinsufficiency of the Mus81-Eme1 endonuclease activates the intra-S-phase and G2/M checkpoints and promotes rereplication in human cells Homologous recombination in DNA repair and DNA damage tolerance Mus81 nuclease and Sgs1 helicase are essential for meiotic recombination in a protist lacking a synaptonemal complex Mus81 endonuclease localizes to nucleoli and to regions of DNA damage in human S-phase cells RNA interference inhibition of Mus81 reduces mitotic recombination in human cells Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells Mus81 functions in the quality control of replication forks at the rDNA and is involved in the maintenance of rDNA repeat number in Saccharomyces cerevisiae Hold your horSSEs: controlling structure-selective endonucleases MUS81 and Yen1/GEN1 Joint molecule resolution requires the redundant activities of MUS-81 and XPF-1 during Caenorhabditis elegans meiosis Crystal structure of the Mus81-Eme1 complex Molecular mimicry of SUMO promotes DNA repair An N-terminal acidic region of Sgs1 interacts with Rpa70 and recruits Rad53 kinase to stalled forks.Functional overlap between Sgs1-Top3 and the Mms4-Mus81 endonuclease Mus81 cleavage of Holliday junctions: a failsafe for processing meiotic recombination intermediates?Esc2 and Sgs1 act in functionally distinct branches of the homologous recombination repair pathway in Saccharomyces cerevisiae.Cooperativity of Mus81.Mms4 with Rad54 in the resolution of recombination and replication intermediates.Checking in on Cds1 (Chk2): A checkpoint kinase and tumor suppressor Multiple-pathway analysis of double-strand break repair mutations in Drosophila Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair Replication foci dynamics: replication patterns are modulated by S-phase checkpoint kinases in fission yeast.Determination of substrate motifs for human Chk1 and hCds1/Chk2 by the oriented peptide library approach.The role of AtMUS81 in interference-insensitive crossovers in A. thaliana MUS81 generates a subset of MLH1-MLH3-independent crossovers in mammalian meiosis.Single Holliday junctions are intermediates of meiotic recombination.Biochemistry of Meiotic Recombination: Formation, Processing, and Resolution of Recombination Intermediates.Human MUS81-EME2 can cleave a variety of DNA structures including intact Holliday junction and nicked duplex.The Mus81-Mms4 structure-selective endonuclease requires nicked DNA junctions to undergo conformational changes and bend its DNA substrates for cleavage.Substrate preference of Gen endonucleases highlights the importance of branched structures as DNA damage repair intermediates.Critical functions of Rpa3/Ssb3 in S-phase DNA damage responses in fission yeast.GEN1/Yen1 and the SLX4 complex: Solutions to the problem of Holliday junction resolution.Replication checkpoint kinase Cds1 regulates Mus81 to preserve genome integrity during replication stress.The extent of error-prone replication restart by homologous recombination is controlled by Exo1 and checkpoint proteins.SUMO-targeted ubiquitin ligase, Rad60, and Nse2 SUMO ligase suppress spontaneous Top1-mediated DNA damage and genome instability.Disruption of murine Mus81 increases genomic instability and DNA damage sensitivity but does not promote tumorigenesis.Redundant mechanisms prevent mitotic entry following replication arrest in the absence of Cdc25 hyper-phosphorylation in fission yeast.Recombinational repair and restart of damaged replication forks.

P2860

Q21090670-F57E2938-4DDE-4AF3-BDFC-58FB5DECA7D5 Q24299599-04A54893-55B9-478F-8585-8BC33DAEC185 Q24318451-9EE32A6B-58C2-4F4C-A3D8-CA2C34BC8337 Q24534960-957F57D3-2AB3-4077-B974-7BBB204A7A68 Q24537482-26EE363A-8CD8-46EB-86B3-E92764401BC1 Q24601150-19E7B387-4AA4-43A3-9A7C-5D7711A78AE3 Q24603667-EE86F0D5-DCB0-48EB-AC4F-40B8E4888491 Q24607828-D5905F0E-300E-4CF8-950A-0E3F424C8C1A Q24627013-3B9984EC-879F-418F-8473-A444FD614E7D Q24644518-D7DB4F7D-6728-47D6-957B-8E029AC22C64 Q24684096-B16561A4-D052-4FB1-9084-7C36A3ED5155 Q26797303-C35F0952-A25C-4169-B8F6-DDDB0578ECDE Q27321836-7C65BDF4-3278-49DD-BF47-EB53D07979FC Q27650328-4B5A7581-D0EF-4C1C-9348-137D310939D2 Q27654705-D9AC0B34-07E6-4BCA-82F7-0B3904DFD450 Q27933571-AF5DCCA8-7ED2-49E6-914F-B1576C30260B Q27935913-96CB2D6C-E24E-4CA9-85D3-BEC584C0887E Q27936167-F94E37FC-3F66-4BA8-A7E3-B521C83876FC Q27937523-27C45936-B413-4955-B540-BD1D42340048 Q27939352-AC1631E5-9988-40F5-8A69-805C655EC00B Q28214285-89F85CC7-7409-4806-8C72-C4A072B61FA3 Q28469182-C81BFD87-0C8C-4A21-9280-D4F15D1764DE Q29618204-020E496B-50F5-4729-8EED-EBF7C16F6F23 Q30479065-DB93461A-48B8-492A-AC0A-95A75C3A6321 Q30804251-2D717089-B2F8-42CF-B390-D987CB2F0ABD Q33294063-2DFC59A2-B947-4232-B759-53561FB8BC91 Q33369076-30BDDB9C-B2FC-4DA3-9186-4FE0B3BA87BC Q33576921-55C92A0B-1287-4A56-891B-D27F0452FB81 Q33604620-E430B579-8355-4383-906B-8A0542AF2BE3 Q33635502-B9855688-765F-48C6-B7E5-6049D319A3D9 Q33698561-D3F1AF40-88DC-4069-B5AA-BDB7121CBA22 Q33701418-AB3FA5DB-C664-4A4C-87AB-3944248F5124 Q33707399-82CB18D0-D629-4AD9-96D5-5B8A2B50053B Q33737790-22A73892-7623-42BE-85E8-A2C0D4FEA836 Q33751481-0B8CB798-FEC0-4B4B-8F2C-AC298635606E Q33822400-BD98ACC8-6517-41F5-BC51-F3DFFE51635F Q33847786-660C0F03-9782-456B-9C66-26CD0C277484 Q33925085-9CE299C4-878D-4982-8AF5-16F64E99D801 Q33952325-214D26A2-F8B5-4E27-8D44-FB20864CD181 Q33962242-A0D1BB05-A4BC-4A7E-BD97-0B167AA41C8A

P2860

Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1

http://www.wikidata.org/entity/Q24551095

description

2000 nî lūn-bûn

@nan

2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2000年の論文

@ja

2000年論文

@yue

2000年論文

@zh-hant

2000年論文

@zh-hk

2000年論文

@zh-mo

2000年論文

@zh-tw

2000年论文

@wuu

name

Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1

@ast

Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1

@en

Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1

@nl

type

label

Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1

@ast

Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1

@en

Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1

@nl

prefLabel

Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1

@ast

Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1

@en

Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1

@nl

P1433

Q24551095-E3EBF80C-8494-4810-8A82-ED93C695714E

P1476

Q24551095-E8C963EE-43CD-4B6E-BF93-E1B23CE29D90

P2093

Q24551095-3195DDCE-E743-4104-9CED-AC07DD8E1F7E

Q24551095-39A75A50-3109-4555-A285-25AB9D0221B8

Q24551095-7685A974-699E-4447-8731-9ED7C55F1B8C

Q24551095-E637BAD2-551E-4806-8F9D-BD97D391A953

Q24551095-F003DEC7-32A3-4108-8C0B-A61407A139A4

Q24551095-F34E77C5-FD0D-4D8B-96C4-63554EDA25BE

P2860

Q24551095-0339A7C7-7159-4935-BFD9-B8F2C52E61B3

Q24551095-15ACF699-42A5-4AAF-828C-DEE1FC8AE639

Q24551095-19E60FEF-8034-43D6-A535-9563CA987290

Q24551095-2EBB62BC-7FFB-47D3-9AE2-C6040D0C99E2

Q24551095-3004AAED-01DE-4F75-BFFF-A93486834A98

Q24551095-3160FC85-AC3E-42CD-BAAF-A302B61590E9

Q24551095-35C9CE36-A22F-4293-8D09-1962099AAFE8

Q24551095-366202C2-A5AF-4EED-8034-462CB8186FA8

Q24551095-3BAFCFCE-B7EC-4D65-AE8D-8B86474B6D6E

Q24551095-3C9A22DA-FD38-4F63-AA1B-3526DC85BD96

P304

Q24551095-B01A20CC-C60B-449D-8C26-D2AD73DEEFF6

P31

Q24551095-C115AB86-D7D3-4F03-B95A-A41727A9918E

P3181

Q24551095-C7600F38-E68A-4FCA-8B85-7A752246E6F8

P356

Q24551095-A6127F24-DD14-40AF-BA62-5722C0D57F05

P407

Q24551095-7AB3EBAB-33D4-4C53-9336-529D2E646DA4

P433

Q24551095-55D63E79-3A2F-40F9-88EF-C49A59875F8B

P478

Q24551095-2F8AB013-0E6A-4348-886B-5F7205B82544

P577

Q24551095-5ABCBF37-DBE7-417B-818E-066485E7DDF3

P698

Q24551095-2EF3EB72-AADE-46BC-80CB-5CE2F8836DB6

P932

Q24551095-F33D373A-98EA-4380-A2A7-63D78D7D5489

P3181

P356

MCB.20.23.8758-8766.2000

P1433

Molecular and Cellular Biology

P1476

Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1

@en

P2093

A Lopez-Girona

http://www.w3.org/2001/XMLSchema#string

H Interthal

http://www.w3.org/2001/XMLSchema#string

M N Boddy

http://www.w3.org/2001/XMLSchema#string

P Russell

http://www.w3.org/2001/XMLSchema#string

P Shanahan

http://www.w3.org/2001/XMLSchema#string

W D Heyer

http://www.w3.org/2001/XMLSchema#string

P2860

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase

Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome

Xeroderma pigmentosum group F caused by a defect in a structure-specific DNA repair endonuclease

Conserved domains in DNA repair proteins and evolution of repair systems

S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe

The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites

Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53

A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage

Holliday junctions accumulate in replication mutants via a RecA homolog-independent mechanism.

P304

8758-66

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

153502

http://www.w3.org/2001/XMLSchema#string

P356

10.1128/MCB.20.23.8758-8766.2000

http://www.w3.org/2001/XMLSchema#string

P407

P433

23

http://www.w3.org/2001/XMLSchema#string

P478

20

http://www.w3.org/2001/XMLSchema#string

P577

2000-12-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

11073977

http://www.w3.org/2001/XMLSchema#string

P932

86503

http://www.w3.org/2001/XMLSchema#string