Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response - Wikidata - thesis-toulmin - TriplyDB

Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response

Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response

http://www.wikidata.org/entity/Q24561444

about

The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor Chromosome breakage after G2 checkpoint release The Prp19/Pso4 core complex undergoes ubiquitylation and structural alterations in response to DNA damage Ataxia-telangiectasia-mutated dependent phosphorylation of Artemis in response to DNA damage.The DNA-dependent protein kinase catalytic subunit phosphorylation sites in human Artemis.DNA-PK autophosphorylation facilitates Artemis endonuclease activity The Pso4 mRNA splicing and DNA repair complex interacts with WRN for processing of DNA interstrand cross-links SNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repair DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM ARTEMIS stabilizes the genome and modulates proliferative responses in multipotent mesenchymal cells The Ku-dependent non-homologous end-joining pathway contributes to low-dose radiation-stimulated cell survival.Artemis-independent functions of DNA-dependent protein kinase in Ig heavy chain class switch recombination and development Non-homologous end joining: emerging themes and unanswered questions.The multifunctional SNM1 gene family: not just nucleases Cytotoxicity associated with artemis overexpression after lentiviral vector-mediated gene transfer.Snm1-deficient mice exhibit accelerated tumorigenesis and susceptibility to infection.The telomeric protein SNM1B/Apollo is required for normal cell proliferation and embryonic development.Mechanism-based screen establishes signalling framework for DNA damage-associated G1 checkpoint response.A structural model for regulation of NHEJ by DNA-PKcs autophosphorylation Nucleases of the metallo-beta-lactamase family and their role in DNA and RNA metabolism.DNA ligase IV and artemis act cooperatively to suppress homologous recombination in human cells: implications for DNA double-strand break repair.Tying the loose ends together in DNA double strand break repair with 53BP1.Unique and redundant functions of ATM and DNA-PKcs during V(D)J recombination Artemis interacts with the Cul4A-DDB1DDB2 ubiquitin E3 ligase and regulates degradation of the CDK inhibitor p27 ATM-dependent phosphorylation of the checkpoint clamp regulates repair pathways and maintains genomic stability Radiation-induced double-strand breaks require ATM but not Artemis for homologous recombination during S-phase.DNA damage: a trigger of innate immunity but a requirement for adaptive immune homeostasis.Candidate protein biodosimeters of human exposure to ionizing radiation.Increased Artemis levels confer radioresistance to both high and low LET radiation exposures.Coordinate 5' and 3' endonucleolytic trimming of terminally blocked blunt DNA double-strand break ends by Artemis nuclease and DNA-dependent protein kinase.Alterations of DNA damage repair pathways resulting from JCV infection.V(D)J and immunoglobulin class switch recombinations: a paradigm to study the regulation of DNA end-joining.DNA double-strand break repair and development.DNA protein kinase-dependent G2 checkpoint revealed following knockdown of ataxia-telangiectasia mutated in human mammary epithelial cells Genetic variations in DNA repair genes, radiosensitivity to cancer and susceptibility to acute tissue reactions in radiotherapy-treated cancer patients.Artemis is a negative regulator of p53 in response to oxidative stress Artemis regulates cell cycle recovery from the S phase checkpoint by promoting degradation of cyclin E.Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining.Reversion of the ErbB malignant phenotype and the DNA damage response.Resolution of complex ends by Nonhomologous end joining - better to be lucky than good?

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Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response

http://www.wikidata.org/entity/Q24561444

description

2004 nî lūn-bûn

@nan

2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2004年の論文

@ja

2004年論文

@yue

2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

Artemis is a phosphorylation t ...... DNA damage checkpoint response

@ast

Artemis is a phosphorylation t ...... DNA damage checkpoint response

@en

Artemis is a phosphorylation t ...... DNA damage checkpoint response

@nl

type

label

Artemis is a phosphorylation t ...... DNA damage checkpoint response

@ast

Artemis is a phosphorylation t ...... DNA damage checkpoint response

@en

Artemis is a phosphorylation t ...... DNA damage checkpoint response

@nl

prefLabel

Artemis is a phosphorylation t ...... DNA damage checkpoint response

@ast

Artemis is a phosphorylation t ...... DNA damage checkpoint response

@en

Artemis is a phosphorylation t ...... DNA damage checkpoint response

@nl

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MCB.24.20.9207-9220.2004

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Molecular and Cellular Biology

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Artemis is a phosphorylation t ...... DNA damage checkpoint response

@en

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Janice Succi

http://www.w3.org/2001/XMLSchema#string

Michael D Story

http://www.w3.org/2001/XMLSchema#string

Randy J Legerski

http://www.w3.org/2001/XMLSchema#string

Sheela Prithivirajsingh

http://www.w3.org/2001/XMLSchema#string

Xiaoshan Zhang

http://www.w3.org/2001/XMLSchema#string

Zhaohui Feng

http://www.w3.org/2001/XMLSchema#string

P2860

DNA end-joining catalyzed by human cell-free extracts

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer

Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

Sequence similarity between the 73-kilodalton protein of mammalian CPSF and a subunit of yeast polyadenylation factor I

DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

Analysis of Rad3 and Chk1 protein kinases defines different checkpoint responses.

Metallo-beta-lactamase fold within nucleic acids processing enzymes: the beta-CASP family.

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9207-20

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scholarly article

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10.1128/MCB.24.20.9207-9220.2004

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20

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24

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2004-10-01T00:00:00Z

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15456891

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phosphorylation

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517881

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