The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13 - Wikidata - thesis-toulmin - TriplyDB

The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13

The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13

http://www.wikidata.org/entity/Q24561857

about

Molecular cloning of six novel Krüppel-like zinc finger genes from hematopoietic cells and identification of a novel transregulatory domain KRNB Human Bex2 interacts with LMO2 and regulates the transcriptional activity of a novel DNA-binding complex Molecular cloning and characterization of SmLIM, a developmentally regulated LIM protein preferentially expressed in aortic smooth muscle cells Association of erythroid transcription factors: complexes involving the LIM protein RBTN2 and the zinc-finger protein GATA1 TAL2, a helix-loop-helix gene activated by the (7;9)(q34;q32) translocation in human T-cell leukemia TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3 Purification and properties of rat cysteine-rich intestinal protein The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24 The HOX11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genes The LIM protein RBTN2 and the basic helix-loop-helix protein TAL1 are present in a complex in erythroid cells Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia Gsh-4 encodes a LIM-type homeodomain, is expressed in the developing central nervous system and is required for early postnatal survival Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in neuronal development Gene therapy for severe combined immunodeficiency: are we there yet?Identification and characterization of LMO4, an LMO gene with a novel pattern of expression during embryogenesis Targeting leukemia stem cells: which pathways drive self-renewal activity in T-cell acute lymphoblastic leukemia?Homeodomain proteins: an update Transcriptional network control of normal and leukaemic haematopoiesis Structural Basis for LMO2-Driven Recruitment of the SCL:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets Conformational flexibility of the oncogenic protein LMO2 primes the formation of the multi-protein transcription complex Analysis of the V(D)J recombination efficiency at lymphoid chromosomal translocation breakpoints The LMO2 oncogene regulates DNA replication in hematopoietic cells Transcriptional activity of TAL1 in T cell acute lymphoblastic leukemia (T-ALL) requires RBTN1 or -2 and induces TALLA1, a highly specific tumor marker of T-ALL Thymic overexpression of Ttg-1 in transgenic mice results in T-cell acute lymphoblastic leukemia/lymphoma Null mutation of the Lmo4 gene or a combined null mutation of the Lmo1/Lmo3 genes causes perinatal lethality, and Lmo4 controls neural tube development in mice The scl gene product is required for the generation of all hematopoietic lineages in the adult mouse Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene Combined interphase fluorescence in situ hybridization elucidates the genetic heterogeneity of T-cell acute lymphoblastic leukemia in adults.Single domain intracellular antibodies from diverse libraries: emphasizing dual functions of LMO2 protein interactions using a single VH domain The leukemia-associated-protein (LAP) domain, a cysteine-rich motif, is present in a wide range of proteins, including MLL, AF10, and MLLT6 proteins.Modeling T-cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes.An scl gene product lacking the transactivation domain induces bony abnormalities and cooperates with LMO1 to generate T-cell malignancies in transgenic mice.The oncogenic T cell LIM-protein Lmo2 forms part of a DNA-binding complex specifically in immature T cells Chromatin immunoselection defines a TAL-1 target gene The LIM domain gene LMO4 inhibits differentiation of mammary epithelial cells in vitro and is overexpressed in breast cancer.Cyclin C is a haploinsufficient tumour suppressor.Conversion of the LIMA1 tumour suppressor into an oncogenic LMO-like protein by API2-MALT1 in MALT lymphoma.Upstream distal regulatory elements contact the Lmo2 promoter in mouse erythroid cells Overexpression Beadex mutations and loss-of-function heldup-a mutations in Drosophila affect the 3' regulatory and coding components, respectively, of the Dlmo gene.

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The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13

http://www.wikidata.org/entity/Q24561857

description

1991 nî lūn-bûn

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1991 թուականի Մայիսին հրատարակուած գիտական յօդուած

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1991 թվականի մայիսին հրատարակված գիտական հոդված

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1991年の論文

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The rhombotin family of cystei ...... an chromosomes 11p15 and 11p13

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The rhombotin family of cystei ...... an chromosomes 11p15 and 11p13

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The rhombotin family of cystei ...... an chromosomes 11p15 and 11p13

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The rhombotin family of cystei ...... an chromosomes 11p15 and 11p13

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The rhombotin family of cystei ...... an chromosomes 11p15 and 11p13

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The rhombotin family of cystei ...... an chromosomes 11p15 and 11p13

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The rhombotin family of cystei ...... an chromosomes 11p15 and 11p13

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The rhombotin family of cystei ...... an chromosomes 11p15 and 11p13

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The rhombotin family of cystei ...... an chromosomes 11p15 and 11p13

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The rhombotin family of cystei ...... an chromosomes 11p15 and 11p13

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L Foroni

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M F Perutz

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P2860

DNA sequencing with chain-terminating inhibitors

An unusual structure of a putative T cell oncogene which allows production of similar proteins from distinct mRNAs

The mechanism of chromosomal translocation t(11;14) involving the T-cell receptor C delta locus on human chromosome 14q11 and a transcribed region of chromosome 11p15

The t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger protein

Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia

Insulin gene enhancer binding protein Isl-1 is a member of a novel class of proteins containing both a homeo- and a Cys-His domain

Expression and purification of the leucine zipper and DNA-binding domains of Fos and Jun: both Fos and Jun contact DNA directly

Human T-cell-receptor delta chain: genomic organization, diversity, and expression in populations of cells.

Zinc fingers, zinc clusters, and zinc twists in DNA-binding protein domains.

A simple technique for generating probes for RNA in situ hybridization: an adjunct to genome mapping exemplified by the RAG-1/RAG-2 gene cluster.

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