PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53
about
Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complexMultiple facets of p53 in senescence induction and maintenanceThe functional diversity of protein lysine methylationMOF-associated complexes ensure stem cell identity and Xist repression.Mutant TP53 posttranslational modifications: challenges and opportunities.Identification of hidden relationships from the coupling of hydrophobic cluster analysis and domain architecture information.An acetyl-methyl switch drives a conformational change in p53.Structural plasticity of methyllysine recognition by the tandem tudor domain of 53BP1A nonsense mutation in the DNA repair factor Hebo causes mild bone marrow failure and microcephaly.Expression of PHF20 protein contributes to good prognosis of NSCLC and is associated with Bax expression.SCF(Fbxo22)-KDM4A targets methylated p53 for degradation and regulates senescence.G9a-mediated methylation of ERα links the PHF20/MOF histone acetyltransferase complex to hormonal gene expression.A Small Protein Associated with Fungal Energy Metabolism Affects the Virulence of Cryptococcus neoformans in Mammals.PHF20 Readers Link Methylation of Histone H3K4 and p53 with H4K16 Acetylation.PHF20 regulates NF-κB signalling by disrupting recruitment of PP2A to p65Methyllysine reader plant homeodomain (PHD) finger protein 20-like 1 (PHF20L1) antagonizes DNA (cytosine-5) methyltransferase 1 (DNMT1) proteasomal degradation.Sprint-interval but not continuous exercise increases PGC-1α protein content and p53 phosphorylation in nuclear fractions of human skeletal muscle.Emerging roles for chromatin as a signal integration and storage platform.Tudor: a versatile family of histone methylation 'readers'.Post-translational control of transcription factors: methylation ranks highly.Biological function and regulation of histone and non-histone lysine methylation in response to DNA damage.Beyond histones - the expanding roles of protein lysine methylation.PHF20 positively regulates osteoblast differentiation via increasing the expression and activation of Runx2 with enrichment of H3K4me3.Identification of genes and pathways potentially related to PHF20 by gene expression profile analysis of glioblastoma U87 cell lineTP53 Regulates Metabolic GenesRegulation of TP53 Activity through Association with Co-factorsThe guardian of the genome p53 regulates exercise-induced mitochondrial plasticity beyond organelle biogenesis.A molecular engineering toolbox for the structural biologist.Cold-water immersion following sprint interval training does not alter endurance signaling pathways or training adaptations in human skeletal muscle.Identification of protein lysine methylation readers with a yeast three-hybrid approach.PHF20 binds TP53 dimethylated on K370 and K382Delineating Crosstalk Mechanisms of the Ubiquitin Proteasome System That Regulate Apoptosis.Altered expression of tumor suppressor PHF20 in myeloproliferative neoplasms.Cancer cell metabolism as new targets for novel designed therapies
P2860
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P2860
PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53
description
2012 nî lūn-bûn
@nan
2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
PHF20 is an effector protein o ...... t stabilizes and activates p53
@ast
PHF20 is an effector protein o ...... t stabilizes and activates p53
@en
PHF20 is an effector protein o ...... t stabilizes and activates p53
@nl
type
label
PHF20 is an effector protein o ...... t stabilizes and activates p53
@ast
PHF20 is an effector protein o ...... t stabilizes and activates p53
@en
PHF20 is an effector protein o ...... t stabilizes and activates p53
@nl
prefLabel
PHF20 is an effector protein o ...... t stabilizes and activates p53
@ast
PHF20 is an effector protein o ...... t stabilizes and activates p53
@en
PHF20 is an effector protein o ...... t stabilizes and activates p53
@nl
P2093
P2860
P3181
P356
P1476
PHF20 is an effector protein o ...... t stabilizes and activates p53
@en
P2093
Aimee I Badeaux
Donghwa Kim
Gaofeng Cui
Georges Mer
James R Thompson
Jin Q Cheng
Joseph Lee
Maria Victoria Botuyan
Mark T Bedford
P2860
P2888
P304
P3181
P356
10.1038/NSMB.2353
P407
P577
2012-09-01T00:00:00Z
P5875
P6179
1007776380