Induced chromosome deletions cause hypersociability and other features of Williams-Beuren syndrome in mice.
about
Reduction of NADPH-oxidase activity ameliorates the cardiovascular phenotype in a mouse model of Williams-Beuren SyndromeUsing transcription modules to identify expression clusters perturbed in Williams-Beuren syndromeAssociation of mouse Dlg4 (PSD-95) gene deletion and human DLG4 gene variation with phenotypes relevant to autism spectrum disorders and Williams' syndromeMultiple autism-like behaviors in a novel transgenic mouse model.Bridging the gene-behavior divide through neuroimaging deletion syndromes: Velocardiofacial (22q11.2 Deletion) and Williams (7q11.23 Deletion) syndromes.Essential role of the N-terminal region of TFII-I in viability and behavior.Induced chromosome deletion in a Williams-Beuren syndrome mouse model causes cardiovascular abnormalities.Intracisternal Gtf2i Gene Therapy Ameliorates Deficits in Cognition and Synaptic Plasticity of a Mouse Model of Williams-Beuren SyndromeNegative autoregulation of GTF2IRD1 in Williams-Beuren syndrome via a novel DNA binding mechanismMapping genetically controlled neural circuits of social behavior and visuo-motor integration by a preliminary examination of atypical deletions with Williams syndromeIn vivo quantification of murine aortic cyclic strain, motion, and curvature: implications for abdominal aortic aneurysm growthAnimal models of psychiatric disorders that reflect human copy number variation.The social phenotype of Williams syndrome.Cognitive-behavioral phenotypes of Williams syndrome are associated with genetic variation in the GTF2I gene, in a healthy population.LIMK1 regulates long-term memory and synaptic plasticity via the transcriptional factor CREB.Dosage-dependent phenotypes in models of 16p11.2 lesions found in autismSensitized phenotypic screening identifies gene dosage sensitive region on chromosome 11 that predisposes to disease in miceTissue specific characterisation of Lim-kinase 1 expression during mouse embryogenesisEndocrine dysfunctions in children with Williams-Beuren syndrome.Modeling and rescue of the vascular phenotype of Williams-Beuren syndrome in patient induced pluripotent stem cells.Smaller and larger deletions of the Williams Beuren syndrome region implicate genes involved in mild facial phenotype, epilepsy and autistic traits.Small cracks in the dam: rare genetic variants provide opportunities to delve into mechanisms of neuropsychiatric disorders.Animal models of Williams syndrome.Gene discovery and functional assessment of rare copy-number variants in neurodevelopmental disorders.Using hiPSCs to model neuropsychiatric copy number variations (CNVs) has potential to reveal underlying disease mechanisms.Structural variants in genes associated with human Williams-Beuren syndrome underlie stereotypical hypersociability in domestic dogs.Modeling Williams syndrome with induced pluripotent stem cells.Metabolic abnormalities in Williams-Beuren syndrome.2012 William Allan Award: Adventures in cytogenetics.The contribution of GTF2I haploinsufficiency to Williams syndrome.The Williams syndrome prosociality gene GTF2I mediates oxytocin reactivity and social anxiety in a healthy population.Rodent models of genetic and chromosomal variations in psychiatric disorders.Heterozygous deletion of the Williams-Beuren syndrome critical interval in mice recapitulates most features of the human disorder.Haploinsufficiency of Gtf2i, a gene deleted in Williams Syndrome, leads to increases in social interactions.Consistent hypersocial behavior in mice carrying a deletion of Gtf2i but no evidence of hyposocial behavior with Gtf2i duplication: Implications for Williams-Beuren syndrome and autism spectrum disorder.Metabolic etiologies in West syndrome.Mouse models of aneuploidy.Elastin, arterial mechanics, and cardiovascular disease
P2860
Q27335096-974FC69A-B60C-4F11-9A79-1DC390E9A9ABQ28476782-66CC3F6E-9371-4330-973C-B1D8EE6CD32BQ28586842-C60A888E-A513-4C60-A845-3735A5F3E3E7Q30469511-E26D1C3C-B2C5-4375-B1BC-9293370ED514Q30472917-875D6E26-487C-4037-9806-A00AFCC43478Q30481565-A80536B3-9BB6-4F4B-A5D1-3C497763EE2DQ30497302-928F69D4-16A2-41D3-8A59-AD441B57273FQ30736046-E0AF874C-EA7A-4DAE-BF97-905A9633A68DQ33717569-52535858-4B22-4258-B8A4-E3148BE57634Q34020534-67AF89C7-5879-42CA-80A2-04E7ECA41D9CQ34286124-BC076986-7203-4FCB-B0BA-9409CE01547DQ34294530-ED85B768-03EE-404F-BB24-69955C020348Q34323414-5C13A1C8-F694-46D4-8744-4F0991197D53Q34587552-E4CD0962-109D-4F03-82E1-4F0966007003Q35214701-6136814C-09C8-4917-932E-3E3CC02BF930Q35345720-14DA1443-56F7-4F09-8124-F768E0266E66Q36108365-36D36745-47D6-41B2-9419-71DE84BDF864Q36126268-3462AE42-63EE-4461-A0A9-D89B24770928Q36809516-6979AA3A-3B01-4EE9-A4C8-ACF3BA4EA1EEQ36861726-05C2FDC0-DA3B-4360-9D6E-0BCC885204B9Q37397610-8BCD457F-478D-4E8E-A63C-4AB064C5A97AQ37593443-3DAC5A95-3643-40B3-8675-2E1B52EDA199Q37738826-0C70AB54-2B02-420B-9AEB-7C089884C626Q38478012-CC56AFEA-12B0-428F-9128-DF165577E6E5Q38637625-FBBD82EB-14A8-420A-B4A9-6BA2A2B92EC6Q38641866-7B5715C5-AFE1-4CB6-9618-C414E904175AQ38947225-3B434301-2556-442F-AAE7-80CAE9CF0A8AQ41461696-CB81F8C9-FF39-4FAC-A2AB-D1CB3CD352B5Q42544481-81C59FA3-76B6-4171-8A17-6A7A74CACA91Q47197380-0A45F915-02A6-40A9-AD36-3F051C97DA2EQ47326415-600A5DAD-A3A3-4F6F-92CA-7DC231D107F3Q48257043-AF521047-8419-4DA5-9810-18838C584882Q48658363-CF4AE018-49CB-4E02-ADF3-DF525BB4BA05Q50312721-8118B1BE-9CCA-49A0-9699-01B88D4B8CAFQ53427776-3BBF2D93-EBE4-49EC-B977-CCD5476DF2C6Q55235450-6343D0FF-A7C2-4DF0-9BF6-F186C9A6F371Q55363878-6D8A920E-ECCE-4F2E-BFC6-B2C64EA03641Q57171390-39C3958F-B477-4F33-8B21-8891933E5392
P2860
Induced chromosome deletions cause hypersociability and other features of Williams-Beuren syndrome in mice.
description
2009 nî lūn-bûn
@nan
2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Induced chromosome deletions c ...... lliams-Beuren syndrome in mice
@nl
Induced chromosome deletions c ...... liams-Beuren syndrome in mice.
@ast
Induced chromosome deletions c ...... liams-Beuren syndrome in mice.
@en
type
label
Induced chromosome deletions c ...... lliams-Beuren syndrome in mice
@nl
Induced chromosome deletions c ...... liams-Beuren syndrome in mice.
@ast
Induced chromosome deletions c ...... liams-Beuren syndrome in mice.
@en
prefLabel
Induced chromosome deletions c ...... lliams-Beuren syndrome in mice
@nl
Induced chromosome deletions c ...... liams-Beuren syndrome in mice.
@ast
Induced chromosome deletions c ...... liams-Beuren syndrome in mice.
@en
P2093
P2860
P3181
P356
P1476
Induced chromosome deletions c ...... liams-Beuren syndrome in mice.
@en
P2093
Alessandra Splendore
Birgit Halm
Corinne M Spencer
Elena Wright
Hong Hua Li
Joseph H Bayle
Katharine C Harrison
Leslie A Meltzer
Madhuri Roy
P2860
P3181
P356
10.1002/EMMM.200900003
P407
P577
2009-04-01T00:00:00Z