Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole - Wikidata - thesis-toulmin - TriplyDB

Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole

Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole

http://www.wikidata.org/entity/Q24614550

about

Comparative genomics of the apicomplexan parasites Toxoplasma gondii and Neospora caninum: Coccidia differing in host range and transmission strategy Autophagy in immunity and inflammation Immune response and immunopathology during toxoplasmosis Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence The activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance against Toxoplasma gondii The gut mucosal immune response to Toxoplasma gondii Determinants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control it Identification of the microsporidian Encephalitozoon cuniculi as a new target of the IFNγ-inducible IRG resistance system The polymorphic pseudokinase ROP5 controls virulence in Toxoplasma gondii by regulating the active kinase ROP18 Phosphorylation of mouse immunity-related GTPase (IRG) resistance proteins is an evasion strategy for virulent Toxoplasma gondii The CD40-autophagy pathway is needed for host protection despite IFN-Γ-dependent immunity and CD40 induces autophagy via control of P21 levels A Toxoplasma gondii pseudokinase inhibits host IRG resistance proteins The E2-like conjugation enzyme Atg3 promotes binding of IRG and Gbp proteins to Chlamydia- and Toxoplasma-containing vacuoles and host resistance.GRA25 is a novel virulence factor of Toxoplasma gondii and influences the host immune response ROP18 is a key factor responsible for virulence difference between Toxoplasma gondii and Neospora caninum.The Toxoplasma pseudokinase ROP5 forms complexes with ROP18 and ROP17 kinases that synergize to control acute virulence in mice.The IFN-γ-inducible GTPase, Irga6, protects mice against Toxoplasma gondii but not against Plasmodium berghei and some other intracellular pathogens.Modulation of innate immunity by Toxoplasma gondii virulence effectors.Strain-dependent host transcriptional responses to Toxoplasma infection are largely conserved in mammalian and avian hosts.Interferon-inducible effector mechanisms in cell-autonomous immunity.Partial protective effect of intranasal immunization with recombinant Toxoplasma gondii rhoptry protein 17 against toxoplasmosis in mice Subversion of host cellular functions by the apicomplexan parasites.The rhoptry proteins ROP18 and ROP5 mediate Toxoplasma gondii evasion of the murine, but not the human, interferon-gamma response.Hammondia hammondi, an avirulent relative of Toxoplasma gondii, has functional orthologs of known T. gondii virulence genes Interferon-γ restricts Toxoplasma gondii development in murine skeletal muscle cells via nitric oxide production and immunity-related GTPases.Parasites paralyze cellular host defense system to promote virulence.Hammondia hammondi harbors functional orthologs of the host-modulating effectors GRA15 and ROP16 but is distinguished from Toxoplasma gondii by a unique transcriptional profile.Autophagy in immunity and cell-autonomous defense against intracellular microbes Have it your way: how polymorphic, injected kinases and pseudokinases enable Toxoplasma to subvert host defenses.Guanylate-binding protein 1 (Gbp1) contributes to cell-autonomous immunity against Toxoplasma gondii.IRG and GBP host resistance factors target aberrant, "non-self" vacuoles characterized by the missing of "self" IRGM proteins CXCR3-dependent CD4⁺ T cells are required to activate inflammatory monocytes for defense against intestinal infection.ATF6beta is a host cellular target of the Toxoplasma gondii virulence factor ROP18.Border maneuvers: deployment of mucosal immune defenses against Toxoplasma gondii.Toxoplasma gondii superinfection and virulence during secondary infection correlate with the exact ROP5/ROP18 allelic combination.IRGM3 contributes to immunopathology and is required for differentiation of antigen-specific effector CD8+ T cells in experimental cerebral malaria Atg5 but not Atg7 in dendritic cells enhances IL-2 and IFN-γ production by Toxoplasma gondii-reactive CD4+ T cells The immunity-related GTPase Irga6 dimerizes in a parallel head-to-head fashion Loss of the interferon-γ-inducible regulatory immunity-related GTPase (IRG), Irgm1, causes activation of effector IRG proteins on lysosomes, damaging lysosomal function and predicting the dramatic susceptibility of Irgm1-deficient mice to infection.The secreted kinase ROP18 defends Toxoplasma's border.

P2860

Q21090491-9078F6BA-738F-4ADC-B89C-DE6BFA932DD7 Q24595707-A035EFE3-4D04-4318-9F42-0ED7B63C8DBC Q24612341-2D5BEF02-B63E-4071-B0EB-A30EC75ED974 Q24617053-BE4D7249-5E17-47F9-AFD2-5E7325130123 Q24617222-5829CBD3-CA35-4235-81E7-97B5686BCE8F Q26863747-753C208F-2114-42A7-B1EB-982B67962C3B Q27321401-4031E402-67D5-4EB8-81E2-795FFDBA3048 Q27323191-98ADA2D0-D3F4-4547-BA10-3B5B1173EDB1 Q27341809-EC1D6E78-97B1-40D9-97E4-491FD8411A99 Q28476607-EDEA58D3-5990-4692-A0BE-0C6D52BBCA90 Q28476673-5C9219FE-56C1-4A54-A245-50F569AB2713 Q28481222-649BD5EB-8233-4C9E-B142-3631D397F775 Q31148891-3759CDEE-D6AE-4768-B53A-EC846102CB08 Q33602978-99AA77D2-4032-4A72-AB74-88BE46922C53 Q33753887-91A1A5B3-043A-41CB-A8C9-BD45CEDA44A4 Q33861156-7E65995C-85BA-416E-AEF2-13092CAD8415 Q33940781-3B06D0C6-4CDB-4B09-816B-CAA8F1C68F73 Q34033981-87E0A31E-9F29-44D6-A385-D762D908A3F2 Q34056304-BE799621-6B83-4F61-BED7-FFDAF66CA930 Q34114819-46FD7CF4-5780-4867-893D-981EEEBEE4C2 Q34257517-0A06E4B7-BE24-4B35-B0D8-0D273D25D96F Q34314006-9505FF7A-895C-42CD-BF36-ED50BF092A27 Q34325516-D1BDF38D-11C5-4FCA-B18D-6698CDE389EB Q34339536-78998F9D-E57A-4738-89F3-CC1D81C0A438 Q34425347-9B5F4DC6-9006-4A0E-ACCA-95D18E462506 Q34470850-C0266E7D-861F-4184-B8F4-B81AB30ED3D9 Q34592579-580A438D-0D08-464E-938C-46ABD8A4325B Q34673845-F763D06E-61C3-41B9-874A-A7728C037A4F Q34697840-D0EB528B-2345-45D3-A38F-8022D6B6F51F Q34697891-C7078151-F914-4108-A038-55F113543EB4 Q34778494-EC9B7A32-A1D2-4F80-8A86-C4AB6963F66C Q35018100-8EF48272-6385-4015-B71B-31C6570D15D3 Q35102296-4DFD5B01-3137-4C28-B430-E821BA3198A8 Q35143581-13C160CF-C89D-435E-B72E-A4B4D2198D62 Q35172341-6E21F61E-340B-4291-ACBA-22B3A8779956 Q35187600-5E70A0D2-7606-4B9F-A894-DDB38D48AAE1 Q35269455-71475CEB-CD60-4647-804B-8DF704EDAC26 Q35943304-8BF80470-DFE1-4638-AB73-0B845407C407 Q35995190-F175AE91-1634-4171-9CD6-18F994ABE9E5 Q36041799-ED0D1537-773B-4962-A18D-51741C2F6229

P2860

Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole

http://www.wikidata.org/entity/Q24614550

description

2010 nî lūn-bûn

@nan

2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Coordinated loading of IRG res ...... gondii parasitophorous vacuole

@ast

Coordinated loading of IRG res ...... gondii parasitophorous vacuole

@en

Coordinated loading of IRG res ...... gondii parasitophorous vacuole

@nl

type

label

Coordinated loading of IRG res ...... gondii parasitophorous vacuole

@ast

Coordinated loading of IRG res ...... gondii parasitophorous vacuole

@en

Coordinated loading of IRG res ...... gondii parasitophorous vacuole

@nl

prefLabel

Coordinated loading of IRG res ...... gondii parasitophorous vacuole

@ast

Coordinated loading of IRG res ...... gondii parasitophorous vacuole

@en

Coordinated loading of IRG res ...... gondii parasitophorous vacuole

@nl

P1433

Q24614550-4E876DB8-76FD-40E2-83E5-D4598E00438B

P1476

Q24614550-61E22670-57DC-4BD3-8FEC-9111BBD7FC26

P2093

Q24614550-1E7C27DA-6004-493D-8C95-C1F75F5CED2B

Q24614550-286BB7BA-3E60-4668-B420-CEA75C0BD0FB

Q24614550-35944982-A02B-4D0F-B414-E462E2EB07A5

Q24614550-683D50CD-EE4A-4629-89CB-8C013B510484

Q24614550-7393871B-61FA-4364-B098-423E4DDF95A0

Q24614550-9C471B87-EF5F-4571-9564-DA90C8BDB7B9

Q24614550-B0D62734-078E-4DA9-ACF4-31E37A76DD14

Q24614550-C54ADE9A-CB41-460F-AB6E-826A8C7D7DBF

Q24614550-C9BAEF9B-D96C-484F-8179-0848F442008F

Q24614550-ED350FBF-0DB4-4CF9-BF33-3CAC3AACF7C8

P2860

Q24614550-01B57B3C-5A42-4D85-A333-85D8CC305E61

Q24614550-03D5322E-8E8C-438B-B2E1-9618A9844334

Q24614550-05C87025-69D2-4B64-97F8-7421B199E6ED

Q24614550-11CC3E6E-BF12-4913-AD35-C9753C3BB5A3

Q24614550-21F0D79D-960F-4CE9-99FB-2966EA01A301

Q24614550-23FD474D-5438-4826-A4A5-D2B50FC666A3

Q24614550-2703D019-6C65-4520-A4FF-2BAE97730E0E

Q24614550-2966B7C1-1154-4AD9-9E4F-280F49D59B69

Q24614550-33E5B202-611D-4D35-9DF0-05BD43D098CA

Q24614550-3E76B03D-715B-4C05-AC78-D6F1A9B16401

P304

Q24614550-605B8DE2-CB2A-44B8-97E1-7F118F9D223C

P31

Q24614550-07A08496-6EFF-49D0-BEE3-471D8B2ECDC5

P3181

Q24614550-9390879A-0C92-411B-9E1E-F23FC3A8C2C8

P356

Q24614550-D1E055D4-0CE6-4162-8999-1B41D27AB96D

P407

Q24614550-C808F582-1FBB-4728-8D9F-96FC68E56971

P433

Q24614550-74C30BCD-CCAD-4CD3-9D6A-C3E08E108675

P478

Q24614550-D11D501A-F26C-4954-9376-C456940897E1

P50

Q24614550-68C3561A-43D6-4F4E-B663-5C728C490616

P577

Q24614550-49257BEA-69A7-47C9-9582-BCDBF7E4B822

P5875

Q24614550-8C544795-0993-47CC-B76F-8A35B6094C51

P698

Q24614550-1A01BB72-DF8E-4010-B3A3-EFF8E3A80604

P921

Q24614550-1444F7F7-F424-47AA-AEFD-B6F0FBD02409

P932

Q24614550-D8756513-DAB5-4225-B440-5DE90683A19A

P3181

P356

J.1462-5822.2010.01443.X

P1433

Cellular Microbiology

P1476

Coordinated loading of IRG res ...... gondii parasitophorous vacuole

@en

P2093

Aliaksandr Khaminets

http://www.w3.org/2001/XMLSchema#string

Daniela Preukschat

http://www.w3.org/2001/XMLSchema#string

Gabriela Reichmann

http://www.w3.org/2001/XMLSchema#string

John C Boothroyd

http://www.w3.org/2001/XMLSchema#string

Jon P Boyle

http://www.w3.org/2001/XMLSchema#string

Jonathan C Howard

http://www.w3.org/2001/XMLSchema#string

Julia P Hunn

http://www.w3.org/2001/XMLSchema#string

Jörn Coers

http://www.w3.org/2001/XMLSchema#string

Yang O Zhao

http://www.w3.org/2001/XMLSchema#string

Yi-Ching Ong

http://www.w3.org/2001/XMLSchema#string

P2860

The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage.

Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death

Localisation and mislocalisation of the interferon-inducible immunity-related GTPase, Irgm1 (LRG-47) in mouse cells

Genome Sequence of an Obligate Intracellular Pathogen of Humans: Chlamydia trachomatis

Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39.

Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases.

The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. 'Protein modifications: beyond the usual suspects' review series

The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy.

IIGP, a member of the IFN inducible and microbial defense mediating 47 kDa GTPase family, interacts with the microtubule binding protein hook3

Mechanisms regulating the positioning of mouse p47 resistance GTPases LRG-47 and IIGP1 on cellular membranes: retargeting to plasma membrane induced by phagocytosis

P304

939-61

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

2200931

http://www.w3.org/2001/XMLSchema#string

P356

10.1111/J.1462-5822.2010.01443.X

http://www.w3.org/2001/XMLSchema#string

P407

P433

7

http://www.w3.org/2001/XMLSchema#string

P478

12

http://www.w3.org/2001/XMLSchema#string

P50

Stephanie Könen-Waisman

P577

2010-07-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

41172482

http://www.w3.org/2001/XMLSchema#string

P698

20109161

http://www.w3.org/2001/XMLSchema#string

P921

Toxoplasma gondii

P932

2901525

http://www.w3.org/2001/XMLSchema#string