Dual epitope recognition by the VASP EVH1 domain modulates polyproline ligand specificity and binding affinity
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Mammalian Fat1 cadherin regulates actin dynamics and cell-cell contactThe intracellular domain of the human protocadherin hFat1 interacts with Homer signalling scaffolding proteinsGLFG and FxFG nucleoporins bind to overlapping sites on importin-betaA WASp-VASP complex regulates actin polymerization at the plasma membrane.Actin-based motility of intracellular microbial pathogensClustering of VASP actively drives processive, WH2 domain-mediated actin filament elongation.Crystal structure of Dcp1p and its functional implications in mRNA decappingThe solution structure of pGolemi, a high affinity Mena EVH1 binding miniature protein, suggests explanations for paralog-specific binding to Ena/VASP homology (EVH) 1 domainsA direct interaction between DCP1 and XRN1 couples mRNA decapping to 5' exonucleolytic degradationArp2/3 complex requires hydrolyzable ATP for nucleation of new actin filamentsA modular toolkit to inhibit proline-rich motif-mediated protein-protein interactions.The structure and function of proline recognition domains.5'-Inositol phosphatase SHIP2 recruits Mena to stabilize invadopodia for cancer cell invasion.Contextual specificity in peptide-mediated protein interactions.Pax6-dependent Shroom3 expression regulates apical constriction during lens placode invaginationEna/VASP regulates mDia2-initiated filopodial length, dynamics, and function.EVH1 domains: structure, function and interactions.Ena/VASP proteins cooperate with the WAVE complex to regulate the actin cytoskeleton.Dcp1 links coactivators of mRNA decapping to Dcp2 by proline recognition.Zyxin is a transforming growth factor-β (TGF-β)/Smad3 target gene that regulates lung cancer cell motility via integrin α5β1.Cytoskeleton assembly at endothelial cell-cell contacts is regulated by alphaII-spectrin-VASP complexes.VASP increases hepatic fatty acid oxidation by activating AMPK in mice.Cellulose-bound peptide arrays: preparation and applications.Fat3 and Ena/VASP proteins influence the emergence of asymmetric cell morphology in the developing retinaProtein kinase G as a therapeutic target for the treatment of metastatic colorectal cancer.Protein kinase D1-mediated phosphorylations regulate vasodilator-stimulated phosphoprotein (VASP) localization and cell migrationMiniature protein ligands for EVH1 domains: interplay between affinity, specificity, and cell motilityAdapter protein SH2B1beta cross-links actin filaments and regulates actin cytoskeletonDiversity of polyproline recognition by EVH1 domains.Differential VASP phosphorylation controls remodeling of the actin cytoskeleton.Enabled negatively regulates diaphanous-driven actin dynamics in vitro and in vivo.Polyproline and triple helix motifs in host-pathogen recognition.ActA of Listeria monocytogenes and Its Manifold Activities as an Important Listerial Virulence Factor.Yersinia protein kinase A phosphorylates vasodilator-stimulated phosphoprotein to modify the host cytoskeleton.Hyperphosphorylation of microfilament-associated proteins is involved in microcystin-LR-induced toxicity in HL7702 cells.Identification of a pivotal endocytosis motif in c-Met and selective modulation of HGF-dependent aggressiveness of cancer using the 16-mer endocytic peptide.Structure-based synthetic mimicry of discontinuous protein binding sites: inhibitors of the interaction of Mena EVH1 domain with proline-rich ligands.Functional analysis of type 1alpha cGMP-dependent protein kinase using green fluorescent fusion proteins.Regulation of VASP by phosphorylation: consequences for cell migration.Abl-1-bridged tyrosine phosphorylation of VASP by Abelson kinase impairs association of VASP to focal adhesions and regulates leukaemic cell adhesion.
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P2860
Dual epitope recognition by the VASP EVH1 domain modulates polyproline ligand specificity and binding affinity
description
2000 nî lūn-bûn
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2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
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2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Dual epitope recognition by th ...... ecificity and binding affinity
@ast
Dual epitope recognition by th ...... ecificity and binding affinity
@en
Dual epitope recognition by th ...... ecificity and binding affinity
@nl
type
label
Dual epitope recognition by th ...... ecificity and binding affinity
@ast
Dual epitope recognition by th ...... ecificity and binding affinity
@en
Dual epitope recognition by th ...... ecificity and binding affinity
@nl
prefLabel
Dual epitope recognition by th ...... ecificity and binding affinity
@ast
Dual epitope recognition by th ...... ecificity and binding affinity
@en
Dual epitope recognition by th ...... ecificity and binding affinity
@nl
P2093
P2860
P356
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Dual epitope recognition by th ...... ecificity and binding affinity
@en
P2093
B Hoffmann
J Schneider-Mergener
P Schmieder
R Volkmer-Engert
P2860
P304
P356
10.1093/EMBOJ/19.18.4903
P407
P577
2000-09-15T00:00:00Z