Ubiquilin-1 is a molecular chaperone for the amyloid precursor protein - Wikidata - thesis-toulmin - TriplyDB

Ubiquilin-1 is a molecular chaperone for the amyloid precursor protein

Ubiquilin-1 is a molecular chaperone for the amyloid precursor protein

http://www.wikidata.org/entity/Q24634983

about

The ubiquilin gene family: evolutionary patterns and functional insights Reduced body weight gain in ubiquilin-1 transgenic mice is associated with increased expression of energy-sensing proteins Association of UBQLN1 mutation with Brown-Vialetto-Van Laere syndrome but not typical ALS.Simvastatin potently induces calcium-dependent apoptosis of human leiomyoma cells.Ubiquilin 2 is not associated with tau pathology Signature changes in ubiquilin expression in the R6/2 mouse model of Huntington's disease.Impacts of Chromatin States and Long-Range Genomic Segments on Aging and DNA Methylation Ubiquilin-1 regulates amyloid precursor protein maturation and degradation by stimulating K63-linked polyubiquitination of lysine 688 Inverse relationship between Alzheimer's disease and cancer, and other factors contributing to Alzheimer's disease: a systematic review.Differential recruitment of UBQLN2 to nuclear inclusions in the polyglutamine diseases HD and SCA3.Pattern of ubiquilin pathology in ALS and FTLD indicates presence of C9ORF72 hexanucleotide expansion.Tau pathology in frontotemporal lobar degeneration with C9ORF72 hexanucleotide repeat expansion Ubiquitin receptors and protein quality control Genes that Affect Brain Structure and Function Identified by Rare Variant Analyses of Mendelian Neurologic Disease.Ubiquilin/Dsk2 promotes inclusion body formation and vacuole (lysosome)-mediated disposal of mutated huntingtin Unbiased screen reveals ubiquilin-1 and -2 highly associated with huntingtin inclusions.Ubiquilin-1 protects cells from oxidative stress and ischemic stroke caused tissue injury in mice.Immunohistochemical analysis of ubiquilin-1 in the human hippocampus: association with neurofibrillary tangle pathology.Protein homeostasis, aging and Alzheimer's disease.Aggrephagy: selective disposal of protein aggregates by macroautophagy.Targeting ubiquilin-1 in Alzheimer's disease.Relationship between amyloid-beta and the ubiquitin-proteasome system in Alzheimer's disease.Ubiquitin pathways in neurodegenerative disease.Proteomic analysis of perfluorooctane sulfonate-induced apoptosis in human hepatic cells using the iTRAQ technique.Overexpression of Ubiquilin-1 Alleviates Alzheimer's Disease-Caused Cognitive and Motor Deficits and Reduces Amyloid-β Accumulation in Mice.Concordance of Several Subcellular Interactions Initiates Alzheimer's Dementia: Their Reversal Requires Combination Treatment.Ubiquilin-1 and protein quality control in Alzheimer disease Unraveling the genes implicated in Alzheimer's disease.Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins.Structures of Rpn1 T1:Rad23 and hRpn13:hPLIC2 Reveal Distinct Binding Mechanisms between Substrate Receptors and Shuttle Factors of the Proteasome.Purification and aggregation of the amyloid precursor protein intracellular domain.Evidence of a link between ubiquilin 2 and optineurin in amyotrophic lateral sclerosis.Ubiquilin-1 immunoreactivity is concentrated on Hirano bodies and dystrophic neurites in Alzheimer's disease brains.Polyubiquitinylation Profile in Down Syndrome Brain Before and After the Development of Alzheimer Neuropathology.Autophagy and Alzheimer's Disease: From Molecular Mechanisms to Therapeutic Implications.Interplay Between the Autophagy-Lysosomal Pathway and the Ubiquitin-Proteasome System: A Target for Therapeutic Development in Alzheimer's Disease.

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Ubiquilin-1 is a molecular chaperone for the amyloid precursor protein

http://www.wikidata.org/entity/Q24634983

description

2011 nî lūn-bûn

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2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

@zh-hk

2011年論文

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2011年論文

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2011年论文

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name

Ubiquilin-1 is a molecular chaperone for the amyloid precursor protein

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Ubiquilin-1 is a molecular chaperone for the amyloid precursor protein

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Ubiquilin-1 is a molecular chaperone for the amyloid precursor protein

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type

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Ubiquilin-1 is a molecular chaperone for the amyloid precursor protein

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Ubiquilin-1 is a molecular chaperone for the amyloid precursor protein

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Ubiquilin-1 is a molecular chaperone for the amyloid precursor protein

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prefLabel

Ubiquilin-1 is a molecular chaperone for the amyloid precursor protein

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Ubiquilin-1 is a molecular chaperone for the amyloid precursor protein

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Ubiquilin-1 is a molecular chaperone for the amyloid precursor protein

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JBC.M111.243147

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Journal of Biological Chemistry

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Ubiquilin-1 is a molecular chaperone for the amyloid precursor protein

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Amina El Ayadi

http://www.w3.org/2001/XMLSchema#string

Andres F Oberhauser

http://www.w3.org/2001/XMLSchema#string

Darren Boehning

http://www.w3.org/2001/XMLSchema#string

Efraín Siller

http://www.w3.org/2001/XMLSchema#string

Emily S Stieren

http://www.w3.org/2001/XMLSchema#string

José M Barral

http://www.w3.org/2001/XMLSchema#string

Megan L Landsverk

http://www.w3.org/2001/XMLSchema#string

Yao Xiao

http://www.w3.org/2001/XMLSchema#string

P2860

The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptide

Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation

A ribosome-associating factor chaperones tail-anchored membrane proteins

The UBL domain of PLIC-1 regulates aggresome formation

Ubiquilin recruits Eps15 into ubiquitin-rich cytoplasmic aggregates via a UIM-UBL interaction

Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD

Ubiquilin regulates presenilin endoproteolysis and modulates gamma-secretase components, Pen-2 and nicastrin

Structural studies of the interaction between ubiquitin family proteins and proteasome subunit S5a

Affinity Makes the Difference: Nonselective Interaction of the UBA Domain of Ubiquilin-1 with Monomeric Ubiquitin and Polyubiquitin Chains

Neuropathological stageing of Alzheimer-related changes

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35689-98

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scholarly article

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10.1074/JBC.M111.243147

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41

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286

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2011-10-14T00:00:00Z

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21852239

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molecular chaperones

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3195644

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