DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms
about
Associating schizophrenia, long non-coding RNAs and neurostructural dynamicsRNA Sequencing in SchizophreniaLong non-coding RNA-dependent transcriptional regulation in neuronal development and diseaseHippocampal neurogenesis as a target for the treatment of mental illness: a critical evaluation.DISC1 at 10: connecting psychiatric genetics and neuroscienceDISC1-binding proteins in neural development, signalling and schizophreniaDISC1: Structure, Function, and Therapeutic Potential for Major Mental IllnessMisassembly of full-length Disrupted-in-Schizophrenia 1 protein is linked to altered dopamine homeostasis and behavioral deficits.Allele-specific regulation of DISC1 expression by miR-135b-5pGene processing control loops suggested by sequencing, splicing, and RNA folding.The DISC1 Ser704Cys substitution affects centrosomal localization of its binding partner PCM1 in glia in human brainSequencing of DISC1 pathway genes reveals increased burden of rare missense variants in schizophrenia patients from a northern Swedish population.Prenatal expression patterns of genes associated with neuropsychiatric disorders.Common genetic variation in Neuregulin 3 (NRG3) influences risk for schizophrenia and impacts NRG3 expression in human brain.Migration defects by DISC1 knockdown in C57BL/6, 129X1/SvJ, and ICR strains via in utero gene transfer and virus-mediated RNAi.Avoiding mouse traps in schizophrenia genetics: lessons and promises from current and emerging mouse models.Disrupted-in-schizophrenia (DISC1) functions presynaptically at glutamatergic synapses.Linking neurodevelopmental and synaptic theories of mental illness through DISC1The long non-coding RNA Gomafu is acutely regulated in response to neuronal activation and involved in schizophrenia-associated alternative splicing.Genetic neuropathology of obsessive psychiatric syndromes.Neuroplasticity signaling pathways linked to the pathophysiology of schizophrenia.Brain expression quantitative trait locus mapping informs genetic studies of psychiatric diseasesDysfunctional gene splicing as a potential contributor to neuropsychiatric disorders.Psychiatric brain banking: three perspectives on current trends and future directions.DISC1 is associated with cortical thickness and neural efficiencyGenetic neuropathology of schizophrenia: new approaches to an old question and new uses for postmortem human brainsCommon functional polymorphisms of DISC1 and cortical maturation in typically developing children and adolescents.Altered axonal targeting and short-term plasticity in the hippocampus of Disc1 mutant mice.Elevated DISC1 transcript levels in PBMCs during acute psychosis in patients with schizophrenia.Half-life of DISC1 protein and its pathological significance under hypoxia stressInterplay between DISC1 and GABA signaling regulates neurogenesis in mice and risk for schizophreniaInteractions of human truncated DISC1 proteins: implications for schizophrenia.SRSF1 and hnRNP H antagonistically regulate splicing of COLQ exon 16 in a congenital myasthenic syndromeMeta-analysis indicates that common variants at the DISC1 locus are not associated with schizophrenia.Genomic DISC1 Disruption in hiPSCs Alters Wnt Signaling and Neural Cell Fate.Common DISC1 polymorphisms disrupt Wnt/GSK3β signaling and brain developmentConvergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction.Association analysis of DISC1 gene polymorphisms with Attention-Deficit Hyperactivity Disorder in Iranian populationTranscriptomic analysis of postmortem brain identifies dysregulated splicing events in novel candidate genes for schizophrenia.A structure-function mechanism for schizophrenia.
P2860
Q26781630-B7C5B3FA-D44F-4550-B11C-44BB33958F26Q26996831-93AA8080-A844-40D6-88A8-85323B3153FFQ26999388-5BEC1059-4CB9-4A73-A8E7-2CCA1C983772Q27687034-ED1C4F40-BC49-4E76-A06C-F234C9E931C8Q28250914-7EE8B4E7-375C-45B0-9FAC-2D6663C8A757Q28302106-756F2328-24D5-411A-882B-16BE9CAA94A5Q28393891-14DBDBA5-E2D4-4B4B-AAEA-EDB8A91A62EAQ30826347-4E002E3A-038A-45D1-A3C1-7D1C26B26B68Q33620861-32C2C319-EA86-46B1-8390-461579CF8E09Q33774731-DAE08A09-5DA7-4357-8661-FB6021EC4AA9Q33878306-B93B6B1F-DC1D-4D95-825F-E9F4B0C831D5Q33997189-BC789379-CC62-4339-A681-F2DC8F079A22Q34075222-CB7AEC06-A513-4D92-97BA-940E4069F837Q34100294-72BBC292-41DC-4E70-AD60-5A3B64AC6A70Q34172976-BD889414-6C27-423A-B24E-C81793D1B3A2Q34206314-45BF51A6-0837-4E3C-A003-F3B95854FEA4Q34222021-A6DF0ACA-EA98-40FE-A01B-BF5A5AE88B76Q34233683-925A673B-8DA3-413E-A3CE-B58F2295A922Q34341876-7004E36D-26E4-4E03-9E28-C7E94EF7D6F7Q34370439-D743F0E1-5A4D-45A5-9DE2-0125563E9FD5Q34423863-A98F675F-E084-40C2-A922-D721307010E6Q34779923-E181CA8F-9DE3-4430-9FD4-36D5A494B539Q34861234-89ED0B28-0AD8-4B96-8917-1DFD1DD05CDEQ35017779-9181253F-16E2-4131-AABC-E0D1FB92E2D7Q35112848-9D4EF41E-98B9-44B0-A137-EDAFEBBE44EBQ35153945-60A52EE2-A80E-4D00-AD97-BEE7BBFD8475Q35182041-D3EE5794-BAE3-48A0-B56B-03EE2B673F85Q35621140-FDF6564A-63FB-4B6B-AA4E-1B826A6BB923Q35738958-1D9C292E-356B-4E4D-B3CE-E77A8338413EQ35802091-8DFFE857-CE9E-4FA4-B5B7-301B5A2B5365Q35804056-E486DE21-222B-4239-AD66-B662D7F8C8B7Q35844201-F8C7941B-E7F0-41A5-A2D5-8C8684D87571Q35964255-B9912C79-0CD6-49E8-B722-FD981DF686D0Q35986264-5590991C-4FD0-484E-9467-C2A16862359EQ36021547-B464E975-01F3-4717-8FC5-55BA0C0CC0E3Q36070647-4C204B07-4D2A-4783-A75A-57138E7C2BCFQ36189837-519DED7B-77BB-49FE-B705-A063EA9ECD2FQ36270140-18C2C25C-A599-4F03-8F5B-8709B4A27317Q36413126-B1A541A5-0978-4FAC-8E42-F17527E6B654Q36493182-48C0E82A-49B4-471F-B3EF-60FE3DD1A9C4
P2860
DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
DISC1 splice variants are upre ...... ciated with risk polymorphisms
@ast
DISC1 splice variants are upre ...... ciated with risk polymorphisms
@en
DISC1 splice variants are upre ...... ciated with risk polymorphisms
@nl
type
label
DISC1 splice variants are upre ...... ciated with risk polymorphisms
@ast
DISC1 splice variants are upre ...... ciated with risk polymorphisms
@en
DISC1 splice variants are upre ...... ciated with risk polymorphisms
@nl
prefLabel
DISC1 splice variants are upre ...... ciated with risk polymorphisms
@ast
DISC1 splice variants are upre ...... ciated with risk polymorphisms
@en
DISC1 splice variants are upre ...... ciated with risk polymorphisms
@nl
P2093
P2860
P356
P1476
DISC1 splice variants are upre ...... ciated with risk polymorphisms
@en
P2093
Barbara K Lipska
Erin N Newburn
Joel E Kleinman
Kenji Nakata
Maxim Barenboim
Radhakrishna Vakkalanka
Thomas M Hyde
Tianzhang Ye
Yoshitatsu Sei
Yukitaka Morita
P2860
P304
P356
10.1073/PNAS.0903413106
P407
P577
2009-09-15T00:00:00Z