Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo - Wikidata - thesis-toulmin - TriplyDB

Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo

Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo

http://www.wikidata.org/entity/Q24648140

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CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis Thrombospondin 1 binding to calreticulin-LRP1 signals resistance to anoikis AIP1 functions as an endogenous inhibitor of VEGFR2-mediated signaling and inflammatory angiogenesis in mice Cooperation between integrin alphavbeta3 and VEGFR2 in angiogenesis Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1 New role for the protein tyrosine phosphatase DEP-1 in Akt activation and endothelial cell survival Akt1 in endothelial cell and angiogenesis Platelet signaling Akt isoforms in vascular disease Stability and function of adult vasculature is sustained by Akt/Jagged1 signalling axis in endothelium.HoxA5 stabilizes adherens junctions via increased Akt1 P21 activated kinase-1 (Pak1) promotes prostate tumor growth and microinvasion via inhibition of transforming growth factor β expression and enhanced matrix metalloproteinase 9 secretion PI3K/PTEN signaling in angiogenesis and tumorigenesis Inhibition of phosphatidylinositol 3-kinase/Akt signaling attenuates hypoxia-induced pulmonary artery remodeling and suppresses CREB depletion in arterial smooth muscle cells Overexpression of CXCL5 is associated with poor survival in patients with pancreatic cancer.Matrix-specific p21-activated kinase activation regulates vascular permeability in atherogenesis.Deletion of tetraspanin Cd151 results in decreased pathologic angiogenesis in vivo and in vitro.Anthrax lethal toxin induces cell death-independent permeability in zebrafish vasculature Cooperative signaling between Slit2 and Ephrin-A1 regulates a balance between angiogenesis and angiostasis.IKKβ regulates essential functions of the vascular endothelium through kinase-dependent and -independent pathways The translation initiation factor eIF3i up-regulates vascular endothelial growth factor A, accelerates cell proliferation, and promotes angiogenesis in embryonic development and tumorigenesis.Modulation of angiogenesis by a tetrameric tripeptide that antagonizes vascular endothelial growth factor receptor 1.System theoretical investigation of human epidermal growth factor receptor-mediated signalling.TGF-beta is required for vascular barrier function, endothelial survival and homeostasis of the adult microvasculature.Novel cell-free strategy for therapeutic angiogenesis: in vitro generated conditioned medium can replace progenitor cell transplantation HER/ErbB receptor interactions and signaling patterns in human mammary epithelial cells Ablation of 3-phosphoinositide-dependent protein kinase 1 (PDK1) in vascular endothelial cells enhances insulin sensitivity by reducing visceral fat and suppressing angiogenesis.Suppression of interactions between prostate tumor cell-surface integrin and endothelial ICAM-1 by simvastatin inhibits micrometastasis c-Cbl inhibition improves cardiac function and survival in response to myocardial ischemia Plastic roles of pericytes in the blood-retinal barrier.ERK1/2-Akt1 crosstalk regulates arteriogenesis in mice and zebrafish.Modulation of growth and angiogenic potential of oral squamous carcinoma cells in vitro using salvianolic acid B.Endothelial PFKFB3 plays a critical role in angiogenesis.The efficacy of the novel dual PI3-kinase/mTOR inhibitor NVP-BEZ235 compared with rapamycin in renal cell carcinoma.Endothelial Akt1 mediates angiogenesis by phosphorylating multiple angiogenic substrates.Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells.Akt/Protein kinase B is required for lymphatic network formation, remodeling, and valve development.Up-regulation of PIK3CA promotes metastasis in gastric carcinoma.Akt and phospholipase Cγ are involved in the regulation of growth and migration of MDA-MB-468 breast cancer and SW480 colon cancer cells when cultured with diabetogenic levels of glucose and insulin.MiR-126-3p suppresses tumor metastasis and angiogenesis of hepatocellular carcinoma by targeting LRP6 and PIK3R2.

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Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo

http://www.wikidata.org/entity/Q24648140

description

2005 nî lūn-bûn

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2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo

@ast

Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo

@en

Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo

@nl

type

label

Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo

@ast

Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo

@en

Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo

@nl

prefLabel

Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo

@ast

Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo

@en

Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo

@nl

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Nature Medicine

P1476

Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo

@en

P2093

Juhua Chen

http://www.w3.org/2001/XMLSchema#string

Nissim Hay

http://www.w3.org/2001/XMLSchema#string

Olga Razorenova

http://www.w3.org/2001/XMLSchema#string

Paul Bornstein

http://www.w3.org/2001/XMLSchema#string

Payaningal R Somanath

http://www.w3.org/2001/XMLSchema#string

Tatiana V Byzova

http://www.w3.org/2001/XMLSchema#string

William S Chen

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P2860

Thrombospondin 2 inhibits microvascular endothelial cell proliferation by a caspase-independent mechanism.

CD36: a critical anti-angiogenic receptor

Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene

Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1

Angiogenesis in cancer, vascular, rheumatoid and other disease

Mechanisms of angiogenesis

Angiogenesis in health and disease

Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry

p21-activated kinase regulates endothelial permeability through modulation of contractility.

Microvascular patterning is controlled by fine-tuning the Akt signal.

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702558

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10.1038/NM1307

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11

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11

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7538388

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1005195476

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16227992

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2277080

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