The RING domain and first zinc finger of TRAF6 coordinate signaling by interleukin-1, lipopolysaccharide, and RANKL - Wikidata - thesis-toulmin - TriplyDB

The RING domain and first zinc finger of TRAF6 coordinate signaling by interleukin-1, lipopolysaccharide, and RANKL

The RING domain and first zinc finger of TRAF6 coordinate signaling by interleukin-1, lipopolysaccharide, and RANKL

http://www.wikidata.org/entity/Q24654977

about

The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB YOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-κB Influence of extracellular zinc on M1 microglial activation.Roles of the TRAF6 and Pellino E3 ligases in MyD88 and RANKL signaling.TRAF-6 dependent signaling pathway is essential for TNF-related apoptosis-inducing ligand (TRAIL) induces osteoclast differentiation Targeted ablation of TRAF6 inhibits skeletal muscle wasting in mice.Deletion of TAK1 in the myeloid lineage results in the spontaneous development of myelomonocytic leukemia in mice Polyubiquitination events mediate polymethylmethacrylate (PMMA) particle activation of NF-kappaB pathway The E3 ubiquitin ligase TRAF6 intercedes in starvation-induced skeletal muscle atrophy through multiple mechanisms TRAF6 protein couples Toll-like receptor 4 signaling to Src family kinase activation and opening of paracellular pathway in human lung microvascular endothelia.Ubiquitin systems mark pathogen-containing vacuoles as targets for host defense by guanylate binding proteins Two Antagonistic MALT1 Auto-Cleavage Mechanisms Reveal a Role for TRAF6 to Unleash MALT1 Activation.R753Q polymorphism inhibits Toll-like receptor (TLR) 2 tyrosine phosphorylation, dimerization with TLR6, and recruitment of myeloid differentiation primary response protein 88 TNF receptor-associated factor 6 (TRAF6) mediates the angiotensin-induced non-canonical TGF-β pathway activation of c-kit(+) cardiac stem cells Tumor necrosis factor receptor-associated factor 6 (TRAF6) and TGFβ-activated kinase 1 (TAK1) play essential roles in the C-type lectin receptor signaling in response to Candida albicans infection.TAK1 is essential for osteoclast differentiation and is an important modulator of cell death by apoptosis and necroptosis.A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation.TRAF molecules in cell signaling and in human diseases CYLD: a tumor suppressor deubiquitinase regulating NF-kappaB activation and diverse biological processes.Cinchonine induces apoptosis of HeLa and A549 cells through targeting TRAF6.Epigallocatechin-3-gallate(EGCG) suppresses melanoma cell growth and metastasis by targeting TRAF6 activity.Tumor necrosis factor receptor- associated factor 6 (TRAF6) regulation of development, function, and homeostasis of the immune system.Cutting Edge: A Cullin-5-TRAF6 Interaction Promotes TRAF6 Polyubiquitination and Lipopolysaccharide Signaling.TRAF6 inhibition rescues dexamethasone-induced muscle atrophy.Functional role of asparaginyl endopeptidase ubiquitination by TRAF6 in tumor invasion and metastasis.Identification of a new NEMO/TRAF6 interface affected in incontinentia pigmenti pathology.Direct, noncatalytic mechanism of IKK inhibition by A20.MicroRNA-351 inhibits denervation-induced muscle atrophy by targeting TRAF6 Oligomerization-primed coiled-coil domain interaction with Ubc13 confers processivity to TRAF6 ubiquitin ligase activity Toll-like Receptor (TLR) Signaling Interacts with CREBH to Modulate High-density Lipoprotein (HDL) in Response to Bacterial Endotoxin.Increased expression of TNF receptor-associated factor 6 after rat traumatic brain injury.A Dithiol Compound Binds to the Zinc Finger Protein TRAF6 and Suppresses Its Ubiquitination.The activity of TRAF RING homo- and heterodimers is regulated by zinc finger 1.The LPS-inducible lncRNA Mirt2 is a negative regulator of inflammation.TRAF6 regulates proliferation of stromal cells in the transition and peripheral zones of benign prostatic hyperplasia via Akt/mTOR signaling.Tumor necrosis factor receptor-associated factor 6 as a nuclear factor kappa B-modulating therapeutic target in cardiovascular diseases: at the heart of it all.Homozygous deletion of RAG1, RAG2 and 5' region TRAF6 causes severe immune suppression and atypical osteopetrosis.Structural insights into the nanomolar affinity of RING E3 ligase ZNRF1 for Ube2N and its functional implications.

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The RING domain and first zinc finger of TRAF6 coordinate signaling by interleukin-1, lipopolysaccharide, and RANKL

http://www.wikidata.org/entity/Q24654977

description

2008 nî lūn-bûn

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2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

The RING domain and first zinc ...... lipopolysaccharide, and RANKL

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The RING domain and first zinc ...... lipopolysaccharide, and RANKL

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The RING domain and first zinc ...... lipopolysaccharide, and RANKL

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label

The RING domain and first zinc ...... lipopolysaccharide, and RANKL

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The RING domain and first zinc ...... lipopolysaccharide, and RANKL

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The RING domain and first zinc ...... lipopolysaccharide, and RANKL

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The RING domain and first zinc ...... lipopolysaccharide, and RANKL

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The RING domain and first zinc ...... lipopolysaccharide, and RANKL

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The RING domain and first zinc ...... lipopolysaccharide, and RANKL

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P1433

Journal of Biological Chemistry

P1476

The RING domain and first zinc ...... lipopolysaccharide, and RANKL

@en

P2093

Alejandro D Campos

http://www.w3.org/2001/XMLSchema#string

Ambily Gopinathan

http://www.w3.org/2001/XMLSchema#string

Betty Lamothe

http://www.w3.org/2001/XMLSchema#string

Bryant G Darnay

http://www.w3.org/2001/XMLSchema#string

Lana Hur

http://www.w3.org/2001/XMLSchema#string

William K Webster

http://www.w3.org/2001/XMLSchema#string

P2860

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

Distinct molecular mechanism for initiating TRAF6 signalling

Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation

TAK1-dependent signaling requires functional interaction with TAB2/TAB3

TRAF6-deficient mice display hypohidrotic ectodermal dysplasia.

FRS2 alpha attenuates FGF receptor signaling by Grb2-mediated recruitment of the ubiquitin ligase Cbl.

Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activation

Interleukin-1 (IL-1) induces the Lys63-linked polyubiquitination of IL-1 receptor-associated kinase 1 to facilitate NEMO binding and the activation of IkappaBalpha kinase

Structure, interactions, and dynamics of the RING domain from human TRAF6

Activation of NF-kappaB by RANK requires tumor necrosis factor receptor-associated factor (TRAF) 6 and NF-kappaB-inducing kinase. Identification of a novel TRAF6 interaction motif

P304

24871-80

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scholarly article

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10.1074/JBC.M802749200

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P433

36

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P478

283

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P577

2008-09-05T00:00:00Z

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P698

18617513

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P921

lipopolysaccharide

P932

2529010

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