Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS - Wikidata - thesis-toulmin - TriplyDB

Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

http://www.wikidata.org/entity/Q24657459

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Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK⁴a regulation H3K27 demethylation by JMJD3 at a poised enhancer of anti-apoptotic gene BCL2 determines ERα ligand dependency Epigenetic regulation of the INK4b-ARF-INK4a locus: in sickness and in health Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers Cellular senescence and tumor suppressor gene p16 Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a ROS, Cell Senescence, and Novel Molecular Mechanisms in Aging and Age-Related Diseases Hypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related Diseases The histone demethylase UTX enables RB-dependent cell fate control A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development Histone demethylase Jumonji D3 (JMJD3) as a tumor suppressor by regulating p53 protein nuclear stabilization A novel zinc finger protein Zfp277 mediates transcriptional repression of the Ink4a/arf locus through polycomb repressive complex 1 Jarid2 regulates mouse epidermal stem cell activation and differentiation Mitogen-activated protein kinase signaling mediates phosphorylation of polycomb ortholog Cbx7.Postnatal development, maturation and aging in the mouse cochlea and their effects on hair cell regeneration.Lysosome-mediated processing of chromatin in senescence.JMJD3 suppresses stem cell-like characteristics in breast cancer cells by downregulation of Oct4 independently of its demethylase activity.Epigenetic repression of p16(INK4A) by latent Epstein-Barr virus requires the interaction of EBNA3A and EBNA3C with CtBP.The localization of histone H3K27me3 demethylase Jmjd3 is dynamically regulated p53 interaction with JMJD3 results in its nuclear distribution during mouse neural stem cell differentiation.Stage-dependent and locus-specific role of histone demethylase Jumonji D3 (JMJD3) in the embryonic stages of lung development.KDM6 demethylase independent loss of histone H3 lysine 27 trimethylation during early embryonic development.A complex secretory program orchestrated by the inflammasome controls paracrine senescence.The molecular balancing act of p16(INK4a) in cancer and aging.The histone demethylase Jarid1b (Kdm5b) is a novel component of the Rb pathway and associates with E2f-target genes in MEFs during senescence.MSK1 triggers the expression of the INK4AB/ARF locus in oncogene-induced senescence.Activation of Bmp2-Smad1 signal and its regulation by coordinated alteration of H3K27 trimethylation in Ras-induced senescence.Epigenetics and cancer.DNA methylation-mediated repression of miR-941 enhances lysine (K)-specific demethylase 6B expression in hepatoma cells.Aging, rejuvenation, and epigenetic reprogramming: resetting the aging clock.The essence of senescence.Independence of repressive histone marks and chromatin compaction during senescent heterochromatic layer formation.Chromatin remodeling, DNA damage repair and aging.Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia.Expression and significance of histone H3K27 demethylases in renal cell carcinoma.2-Oxoglutarate-dependent dioxygenases are sensors of energy metabolism, oxygen availability, and iron homeostasis: potential role in the regulation of aging process.Deregulation of the Ras-Erk Signaling Axis Modulates the Enhancer Landscape.Epstein-Barr virus nuclear antigens 3C and 3A maintain lymphoblastoid cell growth by repressing p16INK4A and p14ARF expression.Human papillomavirus E7 oncoprotein induces KDM6A and KDM6B histone demethylase expression and causes epigenetic reprogramming.

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Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

http://www.wikidata.org/entity/Q24657459

description

2009 nî lūn-bûn

@nan

2009 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի մայիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

@ast

Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

@en

Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

@nl

type

label

Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

@ast

Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

@en

Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

@nl

prefLabel

Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

@ast

Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

@en

Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

@nl

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Genes & Development

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Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

@en

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Emma Anderton

http://www.w3.org/2001/XMLSchema#string

Gordon Peters

http://www.w3.org/2001/XMLSchema#string

Jesús Gil

http://www.w3.org/2001/XMLSchema#string

Marc Rodriguez-Niedenführ

http://www.w3.org/2001/XMLSchema#string

Marta Barradas

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Martin J Walsh

http://www.w3.org/2001/XMLSchema#string

Michaela Banck

http://www.w3.org/2001/XMLSchema#string

Ming-Ming Zhou

http://www.w3.org/2001/XMLSchema#string

Side Li

http://www.w3.org/2001/XMLSchema#string

P2860

The histone H3 lysine 27-specific demethylase Jmjd3 is required for neural commitment

Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth.

Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing

Ligand-dependent activation of the farnesoid X-receptor directs arginine methylation of histone H3 by CARM1

Polycomb CBX7 has a unifying role in cellular lifespan

UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development

The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence

A histone H3 lysine 27 demethylase regulates animal posterior development

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1177-82

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scholarly article

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1736777

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10.1101/GAD.511109

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10

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23

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Goedele Maertens

Juan Carlos Acosta

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2009-05-15T00:00:00Z

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24436041

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19451218

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2685533

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