Human RNA-specific adenosine deaminase ADAR1 transcripts possess alternative exon 1 structures that initiate from different promoters, one constitutively active and the other interferon inducible - Wikidata - thesis-toulmin - TriplyDB

Human RNA-specific adenosine deaminase ADAR1 transcripts possess alternative exon 1 structures that initiate from different promoters, one constitutively active and the other interferon inducible

Human RNA-specific adenosine deaminase ADAR1 transcripts possess alternative exon 1 structures that initiate from different promoters, one constitutively active and the other interferon inducible

http://www.wikidata.org/entity/Q24670551

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A dedicated promoter drives constitutive expression of the cell-autonomous immune resistance GTPase, Irga6 (IIGP1) in mouse liver The large form of ADAR 1 is responsible for enhanced hepatitis delta virus RNA editing in interferon-alpha-stimulated host cells The editing enzyme ADAR1 and the mRNA surveillance protein hUpf1 interact in the cell nucleus Antiviral actions of interferons A left-handed RNA double helix bound by the Z alpha domain of the RNA-editing enzyme ADAR1 RNA editing by adenosine deaminases that act on RNA Modulation of ADAR1 editing activity by Z-RNA in vitro.A-to-I editing of coding and non-coding RNAs by ADARs ADAR1, inosine and the immune sensing system: distinguishing self from non-self New Insights into the Biological Role of Mammalian ADARs; the RNA Editing Proteins Protein kinase PKR and RNA adenosine deaminase ADAR1: new roles for old players as modulators of the interferon response Functions of the RNA Editing Enzyme ADAR1 and Their Relevance to Human Diseases The interactomes of influenza virus NS1 and NS2 proteins identify new host factors and provide insights for ADAR1 playing a supportive role in virus replication Liver disintegration in the mouse embryo caused by deficiency in the RNA-editing enzyme ADAR1 Truncated forms of the dual function human ASCT2 neutral amino acid transporter/retroviral receptor are translationally initiated at multiple alternative CUG and GUG codons Enhancement of replication of RNA viruses by ADAR1 via RNA editing and inhibition of RNA-activated protein kinase RNA-specific adenosine deaminase ADAR1 suppresses measles virus-induced apoptosis and activation of protein kinase PKR Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature Adenosine deaminases acting on RNA (ADARs) are both antiviral and proviral c-Jun amino-terminal kinase-1 mediates glucose-responsive upregulation of the RNA editing enzyme ADAR2 in pancreatic beta-cells ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling Intracellular localization of differentially regulated RNA-specific adenosine deaminase isoforms in inflammation RNA editing enzyme adenosine deaminase is a restriction factor for controlling measles virus replication that also is required for embryogenesis Complex regulation of ADAR-mediated RNA-editing across tissues The dynamic epitranscriptome: A to I editing modulates genetic information Mouse models for Aicardi-Goutières syndrome provide clues to the molecular pathogenesis of systemic autoimmunity ZBP1 subcellular localization and association with stress granules is controlled by its Z-DNA binding domains.p150 ADAR1 isoform involved in maintenance of HeLa cell proliferation.Novel exon of mammalian ADAR2 extends open reading frame.Induction of stress granules by interferon and down-regulation by the cellular RNA adenosine deaminase ADAR1.An RNA editor, adenosine deaminase acting on double-stranded RNA (ADAR1).How does RNA editing affect dsRNA-mediated gene silencing?A PKR-like eukaryotic initiation factor 2alpha kinase from zebrafish contains Z-DNA binding domains instead of dsRNA binding domains Editing of neurotransmitter receptor and ion channel RNAs in the nervous system The RNA editor gene ADAR1 is induced in myoblasts by inflammatory ligands and buffers stress response.CRM1 mediates the export of ADAR1 through a nuclear export signal within the Z-DNA binding domain.Reovirus-mediated induction of ADAR1 (p150) minimally alters RNA editing patterns in discrete brain regions.Tissue selectivity of interferon-stimulated gene expression in mice infected with Dam(+) versus Dam(-) Salmonella enterica serovar Typhimurium strains A-to-I RNA editing and human disease.Tipping the balance: antagonism of PKR kinase and ADAR1 deaminase functions by virus gene products.

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Human RNA-specific adenosine deaminase ADAR1 transcripts possess alternative exon 1 structures that initiate from different promoters, one constitutively active and the other interferon inducible

http://www.wikidata.org/entity/Q24670551

description

1999 nî lūn-bûn

@nan

1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

1999年の論文

@ja

1999年論文

@yue

1999年論文

@zh-hant

1999年論文

@zh-hk

1999年論文

@zh-mo

1999年論文

@zh-tw

1999年论文

@wuu

name

Human RNA-specific adenosine d ...... the other interferon inducible

@ast

Human RNA-specific adenosine d ...... the other interferon inducible

@en

Human RNA-specific adenosine d ...... the other interferon inducible

@nl

type

label

Human RNA-specific adenosine d ...... the other interferon inducible

@ast

Human RNA-specific adenosine d ...... the other interferon inducible

@en

Human RNA-specific adenosine d ...... the other interferon inducible

@nl

prefLabel

Human RNA-specific adenosine d ...... the other interferon inducible

@ast

Human RNA-specific adenosine d ...... the other interferon inducible

@en

Human RNA-specific adenosine d ...... the other interferon inducible

@nl

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Human RNA-specific adenosine d ...... the other interferon inducible

@en

P2093

C E Samuel

http://www.w3.org/2001/XMLSchema#string

C X George

http://www.w3.org/2001/XMLSchema#string

P2860

DNA sequencing with chain-terminating inhibitors

Expression and regulation by interferon of a double-stranded-RNA-specific adenosine deaminase from human cells: evidence for two forms of the deaminase

Functionally distinct double-stranded RNA-binding domains associated with alternative splice site variants of the interferon-inducible double-stranded RNA-specific adenosine deaminase

Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing

Cloning of cDNAs encoding mammalian double-stranded RNA-specific adenosine deaminase

A Z-DNA binding domain present in the human editing enzyme, double-stranded RNA adenosine deaminase

The scanning model for translation: an update

Detection of specific sequences among DNA fragments separated by gel electrophoresis

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer

Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia

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4621-6

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scholarly article

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4330963

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10.1073/PNAS.96.8.4621

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8

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96

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13098532

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10200312

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16382

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