PRC1 is a microtubule binding and bundling protein essential to maintain the mitotic spindle midzone
about
Polo-like kinase 1 directs assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF complex to initiate cleavage furrow formationPlk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cellsDissection of the mammalian midbody proteome reveals conserved cytokinesis mechanisms.C-terminal region of MAP7 domain containing protein 3 (MAP7D3) promotes microtubule polymerization by binding at the C-terminal tail of tubulinChoice of Plk1 docking partners during mitosis and cytokinesis is controlled by the activation state of Cdk1M phase phosphoprotein 1 is a human plus-end-directed kinesin-related protein required for cytokinesisKIF14 and citron kinase act together to promote efficient cytokinesisHuman mitotic spindle-associated protein PRC1 inhibits MgcRacGAP activity toward Cdc42 during the metaphaseMTR120/KIAA1383, a novel microtubule-associated protein, promotes microtubule stability and ensures cytokinesisMarking and measuring single microtubules by PRC1 and kinesin-4Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesisARF6 GTPase protects the post-mitotic midbody from 14-3-3-mediated disintegrationPlk1 negatively regulates PRC1 to prevent premature midzone formation before cytokinesis.PKD2 interacts and co-localizes with mDia1 to mitotic spindles of dividing cells: role of mDia1 IN PKD2 localization to mitotic spindlesThe pre-mRNA-splicing factor SF3a66 functions as a microtubule-binding and -bundling proteinThe dual-specificity phosphatase CDC14B bundles and stabilizes microtubulesRecruitment of MKLP1 to the spindle midzone/midbody by INCENP is essential for midbody formation and completion of cytokinesis in human cellsSpatiotemporal control of spindle midzone formation by PRC1 in human cellsAblation of PRC1 by small interfering RNA demonstrates that cytokinetic abscission requires a central spindle bundle in mammalian cells, whereas completion of furrowing does notCell cycle-dependent translocation of PRC1 on the spindle by Kif4 is essential for midzone formation and cytokinesis.Role of the midbody matrix in cytokinesis: RNAi and genetic rescue analysis of the mammalian motor protein CHO1.Essential roles of KIF4 and its binding partner PRC1 in organized central spindle midzone formationThe 3Ms of central spindle assembly: microtubules, motors and MAPsCep55, a microtubule-bundling protein, associates with centralspindlin to control the midbody integrity and cell abscission during cytokinesisA novel human protein of the maternal centriole is required for the final stages of cytokinesis and entry into S phaseMig12, a novel Opitz syndrome gene product partner, is expressed in the embryonic ventral midline and co-operates with Mid1 to bundle and stabilize microtubulesGrowth, interaction, and positioning of microtubule asters in extremely large vertebrate embryo cellsRecruitment of Polo kinase to the spindle midzone during cytokinesis requires the Feo/Klp3A complexAugmin shapes the anaphase spindle for efficient cytokinetic furrow ingression and abscissionCYK4 promotes antiparallel microtubule bundling by optimizing MKLP1 neck conformationKinetochore components are required for central spindle assembly.MAP65 coordinate microtubule growth during bundle formation.The fission yeast XMAP215 homolog Dis1p is involved in microtubule bundle organizationThe Drosophila microtubule-associated protein mars stabilizes mitotic spindles by crosslinking microtubules through its N-terminal regionOverlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores.Newly Characterized Region of CP190 Associates with Microtubules and Mediates Proper Spindle Morphology in Drosophila Stem CellsProtein dynamics in individual human cells: experiment and theoryCdc14-regulated midzone assembly controls anaphase BThe molecular function of Ase1p: evidence for a MAP-dependent midzone-specific spindle matrix. Microtubule-associated proteinsKinesins to the core: The role of microtubule-based motor proteins in building the mitotic spindle midzone
P2860
Q21092734-3D4BA437-1A8E-461D-BA53-779C6D32556CQ21563540-569C351B-D067-4F2D-87E8-1B9CE57F7506Q24294556-D23815F6-FF2A-43E7-A42B-D9AA814127D6Q24299178-265EB300-E25C-40BB-918D-82EEFBB6524FQ24299765-8F93B4E5-56DD-477B-8BDA-A5A5F6BEB4DAQ24301609-854B4629-6192-475E-8DE4-AEB55A1FE807Q24301784-E0036947-3647-418F-BD52-2C14F7D6C9E2Q24306385-A0086269-D46E-4304-B84D-4FFAD2439AD5Q24306936-45CD7E1F-E788-4470-9D5D-3CC5CC63B195Q24310099-1B814980-2754-433A-B82F-AC311E82561DQ24317964-E49AB87E-311B-4BA1-8A1E-C8D66789526FQ24321392-BE92DA40-A9B6-47CC-86F8-0C9F56565325Q24329251-31C16BD6-5825-42DF-9608-9CE7A2440F1AQ24338591-C0710946-D26A-4FCE-B7F0-7B30F24FE63FQ24528117-811CE269-D7D6-406F-9639-41628F55B927Q24529075-C6F82E85-AC47-4544-AF52-AB4D8634DCF6Q24531219-48652020-9FDB-4F2D-9D03-8D441C85E718Q24546385-19B419D6-5579-4706-803B-76F3371F24D1Q24556579-6B5FE566-5587-47DD-BECE-88937801E2F3Q24557528-89071944-ED93-49E4-AFA0-A116C181A7CBQ24561647-5D8A6C00-34D9-45A2-88BE-23D6DF241B75Q24563319-5E572BF1-D27A-442F-9CAF-600E5884F5B7Q24645077-4F3792D4-6497-448C-A857-5557703E3819Q24670163-C80012A1-1E57-4F74-87C7-D8FE81A39296Q24675061-E34E1234-B9DE-498F-9010-03F4BD7ADF1EQ24803465-45017916-99C4-4639-8598-60304EE50B53Q27011358-04CBC98C-3F09-4BE4-9846-C512266B2AD6Q27302949-520A4CD7-1A0D-4542-8223-17C781FBCAC4Q27306243-C0DA9BA2-EA34-4CB3-93A8-1FEB7A9B1D9CQ27312358-D88AC9FC-246A-4FDF-9457-482FF33F2D72Q27313276-380703D3-96D4-4E96-B66B-303D43596820Q27313972-8B3E8D3C-6A64-4591-B39D-6740EE0C83F7Q27316044-6B41AFDF-430B-4A0D-9BC2-02DEDF75A468Q27329822-7A16963F-E9D8-46EB-AACF-F0453BF55A69Q27335480-A9A397D9-E453-4745-88D0-0E9FAFFAF75EQ27336132-2BF3B9B7-9873-46DD-9F09-4DB35E0F19FFQ27350246-59413E5E-5780-4EC1-9D0B-DDE05E89CE90Q27930729-E73E805C-E761-4E74-BC26-D5A235A88597Q27932270-6D9F093C-A0DB-4687-A207-1792A469FE17Q28271618-081ED661-FC3D-4817-B4A6-9E265F817148
P2860
PRC1 is a microtubule binding and bundling protein essential to maintain the mitotic spindle midzone
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
PRC1 is a microtubule binding ...... in the mitotic spindle midzone
@ast
PRC1 is a microtubule binding ...... in the mitotic spindle midzone
@en
PRC1 is a microtubule binding ...... in the mitotic spindle midzone
@nl
type
label
PRC1 is a microtubule binding ...... in the mitotic spindle midzone
@ast
PRC1 is a microtubule binding ...... in the mitotic spindle midzone
@en
PRC1 is a microtubule binding ...... in the mitotic spindle midzone
@nl
prefLabel
PRC1 is a microtubule binding ...... in the mitotic spindle midzone
@ast
PRC1 is a microtubule binding ...... in the mitotic spindle midzone
@en
PRC1 is a microtubule binding ...... in the mitotic spindle midzone
@nl
P2093
P2860
P50
P356
P1476
PRC1 is a microtubule binding ...... in the mitotic spindle midzone
@en
P2093
Robert L Margolis
Tony Hunter
P2860
P304
P356
10.1083/JCB.200111052
P407
P577
2002-06-24T00:00:00Z