Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage
about
Dissociation of cohesin from chromosome arms and loss of arm cohesion during early mitosis depends on phosphorylation of SA2.Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpointMDC1 is a mediator of the mammalian DNA damage checkpointThe cohesin SMC3 is a target the for beta-catenin/TCF4 transactivation pathwayMSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylationATM-dependent phosphorylation of ATF2 is required for the DNA damage responseCoordination of DNA damage responses via the Smc5/Smc6 complexThe cohesin complex is required for the DNA damage-induced G2/M checkpoint in mammalian cellsRPGR-ORF15, which is mutated in retinitis pigmentosa, associates with SMC1, SMC3, and microtubule transport proteinsHuman Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpointThe combined status of ATM and p53 link tumor development with therapeutic responseCdc7-Dbf4 and the human S checkpoint response to UVCBRCA Mutations, DNA Repair Deficiency, and Ovarian AgingMechanisms of cohesin-mediated gene regulation and lessons learned from cohesinopathiesThe ancient and evolving roles of cohesin in gene expression and DNA repairA new thermosensitive smc-3 allele reveals involvement of cohesin in homologous recombination in C. elegansInvolvement of global genome repair, transcription coupled repair, and chromatin remodeling in UV DNA damage response changes during developmentStructure of a Second BRCT Domain Identified in the Nijmegen Breakage Syndrome Protein Nbs1 and its Function in an MDC1-Dependent Localization of Nbs1 to DNA Damage SitesStructure and DNA binding activity of the mouse condensin hinge domain highlight common and diverse features of SMC proteinsAutophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks.Ataxia-telangiectasia-mutated dependent phosphorylation of Artemis in response to DNA damage.SMC1 coordinates DNA double-strand break repair pathways.Esc4p, a new target of Mec1p (ATR), promotes resumption of DNA synthesis after DNA damage.Nibrin forkhead-associated domain and breast cancer C-terminal domain are both required for nuclear focus formation and phosphorylationDNA damage activates ATM through intermolecular autophosphorylation and dimer dissociationMDC1 is required for the intra-S-phase DNA damage checkpointSpatial organization of the mammalian genome surveillance machinery in response to DNA strand breaksNuclear ataxia-telangiectasia mutated (ATM) mediates the cellular response to DNA double strand breaks in human neuron-like cellsA role for the Tip60 histone acetyltransferase in the acetylation and activation of ATMTargeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiationCell-cycle checkpoints and cancerCohesin: functions beyond sister chromatid cohesionCohesin Is limiting for the suppression of DNA damage-induced recombination between homologous chromosomesInvolvement of Hus1 in the chain elongation step of DNA replication after exposure to camptothecin or ionizing radiationProtein quantitative trait loci identify novel candidates modulating cellular response to chemotherapySeparase loss of function cooperates with the loss of p53 in the initiation and progression of T- and B-cell lymphoma, leukemia and aneuploidy in miceA Surveillance Mechanism Ensures Repair of DNA Lesions during Zygotic ReprogrammingATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaksDNA damage response as a candidate anti-cancer barrier in early human tumorigenesisDNA IR-Double Strand Breaks (DSBs) and cellular response via ATM
P2860
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P2860
Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage
description
2002 nî lūn-bûn
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2002 թուականի Մարտին հրատարակուած գիտական յօդուած
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2002 թվականի մարտին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
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2002年論文
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2002年論文
@zh-hk
2002年論文
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2002年論文
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2002年论文
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name
Involvement of the cohesin pro ...... endent responses to DNA damage
@ast
Involvement of the cohesin pro ...... endent responses to DNA damage
@en
Involvement of the cohesin pro ...... endent responses to DNA damage
@nl
type
label
Involvement of the cohesin pro ...... endent responses to DNA damage
@ast
Involvement of the cohesin pro ...... endent responses to DNA damage
@en
Involvement of the cohesin pro ...... endent responses to DNA damage
@nl
prefLabel
Involvement of the cohesin pro ...... endent responses to DNA damage
@ast
Involvement of the cohesin pro ...... endent responses to DNA damage
@en
Involvement of the cohesin pro ...... endent responses to DNA damage
@nl
P2093
P2860
P3181
P356
P1433
P1476
Involvement of the cohesin pro ...... endent responses to DNA damage
@en
P2093
Michael B Kastan
Seong-Tae Kim
P2860
P304
P3181
P356
10.1101/GAD.970602
P407
P577
2002-03-01T00:00:00Z