EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells
about
Functional characterization of EZH2β reveals the increased complexity of EZH2 isoforms involved in the regulation of mammalian gene expressionPolycomb group genes: keeping stem cell activity in balanceSustained JNK1 activation is associated with altered histone H3 methylations in human liver cancerPhosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cellsComposition and histone substrates of polycomb repressive group complexes change during cellular differentiationCorepressor protein CDYL functions as a molecular bridge between polycomb repressor complex 2 and repressive chromatin mark trimethylated histone lysine 27Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locusCyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2Suz12 is essential for mouse development and for EZH2 histone methyltransferase activityRegulation of DU145 prostate cancer cell growth by Scm-like with four mbt domains 2Heparanase 2 interacts with heparan sulfate with high affinity and inhibits heparanase activityBRCA1 is a negative modulator of the PRC2 complexmiR-101 is down-regulated in glioblastoma resulting in EZH2-induced proliferation, migration, and angiogenesisCovalent histone modifications--miswritten, misinterpreted and mis-erased in human cancersLong non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasisEpigenetic transcriptional repression of cellular genes by a viral SET proteinHOTAIR: Flight of noncoding RNAs in cancer metastasisEZH2 methyltransferase and H3K27 methylation in breast cancerRegulation of chromatin by histone modificationsGolgi protein GOLM1 is a tissue and urine biomarker of prostate cancerMetabolomic profiles delineate potential role for sarcosine in prostate cancer progressionMel-18 acts as a tumor suppressor by repressing Bmi-1 expression and down-regulating Akt activity in breast cancer cellsALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcomeCXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculatureMel-18, a polycomb group protein, regulates cell proliferation and senescence via transcriptional repression of Bmi-1 and c-Myc oncoproteinsPrognostic meta-signature of breast cancer developed by two-stage mixture modeling of microarray dataThe SET-domain protein superfamily: protein lysine methyltransferasesInternet-based Profiler system as integrative framework to support translational research.Targeting histone methylation for cancer therapy: enzymes, inhibitors, biological activity and perspectivesPost-translational modification-regulated leukocyte adhesion and migrationTargeting EZH2 in cancerThe role of the oncofetal H19 lncRNA in tumor metastasis: orchestrating the EMT-MET decisionEZH2 in normal hematopoiesis and hematological malignanciesSynthesis of lysine methyltransferase inhibitorsPRC2 during vertebrate organogenesis: a complex in transitionChemical probes of histone lysine methyltransferasesCommon features of chromatin in aging and cancer: cause or coincidence?Epigenetics in breast cancer: what's new?Chromatin targeting drugs in cancer and immunityGain-of-function mutation of chromatin regulators as a tumorigenic mechanism and an opportunity for therapeutic intervention
P2860
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P2860
EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells
description
2003 nî lūn-bûn
@nan
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
EZH2 is a marker of aggressive ...... ion of breast epithelial cells
@ast
EZH2 is a marker of aggressive ...... ion of breast epithelial cells
@en
EZH2 is a marker of aggressive ...... ion of breast epithelial cells
@nl
type
label
EZH2 is a marker of aggressive ...... ion of breast epithelial cells
@ast
EZH2 is a marker of aggressive ...... ion of breast epithelial cells
@en
EZH2 is a marker of aggressive ...... ion of breast epithelial cells
@nl
prefLabel
EZH2 is a marker of aggressive ...... ion of breast epithelial cells
@ast
EZH2 is a marker of aggressive ...... ion of breast epithelial cells
@en
EZH2 is a marker of aggressive ...... ion of breast epithelial cells
@nl
P2093
P2860
P3181
P356
P1476
EZH2 is a marker of aggressive ...... ion of breast epithelial cells
@en
P2093
Arie P Otte
Arul M Chinnaiyan
Celina G Kleer
Daniel F Hayes
Donna Livant
Ichiro Ota
Mark A Rubin
Michael S Sabel
Richard G A B Sewalt
P2860
P304
P3181
P356
10.1073/PNAS.1933744100
P407
P577
2003-09-30T00:00:00Z