BDNF-induced TrkB activation down-regulates the K+-Cl- cotransporter KCC2 and impairs neuronal Cl- extrusion - Wikidata - thesis-toulmin - TriplyDB

BDNF-induced TrkB activation down-regulates the K+-Cl- cotransporter KCC2 and impairs neuronal Cl- extrusion

BDNF-induced TrkB activation down-regulates the K+-Cl- cotransporter KCC2 and impairs neuronal Cl- extrusion

http://www.wikidata.org/entity/Q24673062

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Role of the neuronal K-Cl co-transporter KCC2 in inhibitory and excitatory neurotransmission Ventral tegmental area BDNF induces an opiate-dependent-like reward state in naive rats SNARE-dependent upregulation of potassium chloride co-transporter 2 activity after metabotropic zinc receptor activation in rat cortical neurons in vitro NMDA receptor activity downregulates KCC2 resulting in depolarizing GABAA receptor-mediated currents Brain-derived neurotrophic factor Two developmental switches in GABAergic signalling: the K+-Cl- cotransporter KCC2 and carbonic anhydrase CAVII Neurotrophic Factors and Their Potential Applications in Tissue Regeneration.Development and regulation of chloride homeostasis in the central nervous system Expanding Spectrum of Sodium Potassium Chloride Co-transporters in the Pathophysiology of Diseases Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2 The role of ovarian hormone-derived neurosteroids on the regulation of GABAA receptors in affective disorders Microglia and spinal cord synaptic plasticity in persistent pain Current view on the functional regulation of the neuronal K(+)-Cl(-) cotransporter KCC2 Growth factors for the treatment of ischemic brain injury (growth factor treatment)Reduced tonic inhibition after stroke promotes motor performance and epileptic seizures.Overexpression of BDNF increases excitability of the lumbar spinal network and leads to robust early locomotor recovery in completely spinalized rats Spreading depression sends microglia on Lévy flights Spinal Plasticity and Behavior: BDNF-Induced Neuromodulation in Uninjured and Injured Spinal Cord Molecular and evolutionary insights into the structural organization of cation chloride cotransporters The RCC1 domain of protein associated with Myc (PAM) interacts with and regulates KCC2 Alterations in Brain Inflammation, Synaptic Proteins, and Adult Hippocampal Neurogenesis during Epileptogenesis in Mice Lacking Synapsin2 BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain Slow intracellular accumulation of GABA(A) receptor delta subunit is modulated by brain-derived neurotrophic factor Nitric oxide signaling modulates synaptic inhibition in the superior paraolivary nucleus (SPN) via cGMP-dependent suppression of KCC2.Disrupted dentate granule cell chloride regulation enhances synaptic excitability during development of temporal lobe epilepsy.KCC2 expression promotes the termination of cortical interneuron migration in a voltage-sensitive calcium-dependent manner.A randomised controlled trial of bumetanide in the treatment of autism in children Decreased CREB levels suppress epilepsy Acute TrkB inhibition rescues phenobarbital-resistant seizures in a mouse model of neonatal ischemia Physiological bases of the K+ and the glutamate/GABA hypotheses of epilepsy.Increase in Bcl-2 phosphorylation and reduced levels of BH3-only Bcl-2 family proteins in kainic acid-mediated neuronal death in the rat brain.Disinhibition mediates a form of hippocampal long-term potentiation in area CA1.Epileptogenesis in the immature brain: emerging mechanisms.KCC2 downregulation facilitates epileptic seizures.Novel repression of Kcc2 transcription by REST-RE-1 controls developmental switch in neuronal chloride.Impairment of kindling development in phospholipase Cγ1 heterozygous mice.Neuronal Chloride Regulation via KCC2 Is Modulated through a GABAB Receptor Protein Complex.BDNF modulates GABAA receptors microtransplanted from the human epileptic brain to Xenopus oocytes.Dual regulation of miRNA biogenesis generates target specificity in neurotrophin-induced protein synthesis.A novel regulatory locus of phosphorylation in the C terminus of the potassium chloride cotransporter KCC2 that interferes with N-ethylmaleimide or staurosporine-mediated activation.

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P2860

BDNF-induced TrkB activation down-regulates the K+-Cl- cotransporter KCC2 and impairs neuronal Cl- extrusion

http://www.wikidata.org/entity/Q24673062

description

2002 nî lūn-bûn

@nan

2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

BDNF-induced TrkB activation d ...... impairs neuronal Cl- extrusion

@ast

BDNF-induced TrkB activation d ...... impairs neuronal Cl- extrusion

@en

BDNF-induced TrkB activation d ...... impairs neuronal Cl- extrusion

@nl

type

label

BDNF-induced TrkB activation d ...... impairs neuronal Cl- extrusion

@ast

BDNF-induced TrkB activation d ...... impairs neuronal Cl- extrusion

@en

BDNF-induced TrkB activation d ...... impairs neuronal Cl- extrusion

@nl

prefLabel

BDNF-induced TrkB activation d ...... impairs neuronal Cl- extrusion

@ast

BDNF-induced TrkB activation d ...... impairs neuronal Cl- extrusion

@en

BDNF-induced TrkB activation d ...... impairs neuronal Cl- extrusion

@nl

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BDNF-induced TrkB activation d ...... impairs neuronal Cl- extrusion

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Avtandil Nanobashvili

http://www.w3.org/2001/XMLSchema#string

Claudio Rivera

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Hannele Lahtinen

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Hong Li

http://www.w3.org/2001/XMLSchema#string

Judith Thomas-Crusells

http://www.w3.org/2001/XMLSchema#string

Juha Voipio

http://www.w3.org/2001/XMLSchema#string

Kai Kaila

http://www.w3.org/2001/XMLSchema#string

Mart Saarma

http://www.w3.org/2001/XMLSchema#string

Matti S Airaksinen

http://www.w3.org/2001/XMLSchema#string

Tero Viitanen

http://www.w3.org/2001/XMLSchema#string

P2860

Neurotrophins: roles in neuronal development and function

Molecular characterization of a putative K-Cl cotransporter in rat brain. A neuronal-specific isoform

The K+/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation

Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early synaptic inhibition

A simple method for organotypic cultures of nervous tissue

BDNF and epilepsy: too much of a good thing?

Kainate, a double agent that generates seizures: two decades of progress.

The KCl cotransporter, KCC2, is highly expressed in the vicinity of excitatory synapses in the rat hippocampus.

The process of epileptogenesis: a pathophysiological approach.

Inhibition of GABAA synaptic responses by brain-derived neurotrophic factor (BDNF) in rat hippocampus.

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10.1083/JCB.200209011

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5

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159

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10997718

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12473684

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2173387

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