Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1 - Wikidata - thesis-toulmin - TriplyDB

Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1

Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1

http://www.wikidata.org/entity/Q24681460

about

Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism The glucose-responsive transcription factor ChREBP contributes to glucose-dependent anabolic synthesis and cell proliferation Links between metabolism and cancer HIF-1: upstream and downstream of cancer metabolism Targeting Cancer Metabolism - Revisiting the Warburg Effects Redox Homeostasis and Cellular Antioxidant Systems: Crucial Players in Cancer Growth and Therapy Anticancer strategies based on the metabolic profile of tumor cells: therapeutic targeting of the Warburg effect Mitochondria in Cancer Energy Metabolism: Culprits or Bystanders?Targeting Tumor Metabolism for Cancer Treatment: Is Pyruvate Dehydrogenase Kinases (PDKs) a Viable Anticancer Target?Is cancer a metabolic disease?Restoration of mitochondria function as a target for cancer therapy Autophagy: a targetable linchpin of cancer cell metabolism P53/microRNA-34-induced metabolic regulation: new opportunities in anticancer therapy Cancer cell metabolism: implications for therapeutic targets Small-molecule inhibitors of the Myc oncoprotein HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression The Caenorhabditis elegans Myc-Mondo/Mad complexes integrate diverse longevity signals MYC is a metastasis gene for non-small-cell lung cancer Changing perspective on oncometabolites: from metabolic signature of cancer to tumorigenic and immunosuppressive agents Reprogramming of glucose metabolism in hepatocellular carcinoma: Progress and prospects Tumor Microenvironment Metabolism: A New Checkpoint for Anti-Tumor Immunity Metabolic consequences of oncogenic IDH mutations Extracellular lumican inhibits pancreatic cancer cell growth and is associated with prolonged survival after surgery Anoikis resistance: an essential prerequisite for tumor metastasis Systems-scale analysis reveals pathways involved in cellular response to methamphetamine Clotrimazole preferentially inhibits human breast cancer cell proliferation, viability and glycolysis Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells Different Mechanisms of Regulation of the Warburg Effect in Lymphoblastoid and Burkitt Lymphoma Cells The oncogene c-Myc coordinates regulation of metabolic networks to enable rapid cell cycle entry HIF-1 inhibition decreases systemic vascular remodelling diseases by promoting apoptosis through a hexokinase 2-dependent mechanism MYC on the path to cancer The Interplay between Oncogenic Signaling Networks and Mitochondrial Dynamics.tRNA synthetase counteracts c-Myc to develop functional vasculature.The Warburg effect is genetically determined in inherited pheochromocytomas Induction of ectopic Myc target gene JAG2 augments hypoxic growth and tumorigenesis in a human B-cell model.Thermodynamics in Gliomas: Interactions between the Canonical WNT/Beta-Catenin Pathway and PPAR Gamma Long term effect of curcumin in regulation of glycolytic pathway and angiogenesis via modulation of stress activated genes in prevention of cancer Dicumarol inhibits PDK1 and targets multiple malignant behaviors of ovarian cancer cells.Racial disparity in metabolic regulation of cancer.Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy?

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Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1

http://www.wikidata.org/entity/Q24681460

description

2007 nî lūn-bûn

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2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2007 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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Hypoxia-inducible factor 1 and ...... yruvate dehydrogenase kinase 1

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Hypoxia-inducible factor 1 and ...... yruvate dehydrogenase kinase 1

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Hypoxia-inducible factor 1 and ...... yruvate dehydrogenase kinase 1

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Hypoxia-inducible factor 1 and ...... yruvate dehydrogenase kinase 1

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Molecular and Cellular Biology

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Hypoxia-inducible factor 1 and ...... yruvate dehydrogenase kinase 1

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Gregg L Semenza

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Ping Gao

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Yen-Chun Liu

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P2860

A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells

The Hallmarks of Cancer

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling

Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL

HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1

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7381-7393

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scholarly article

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10.1128/MCB.00440-07

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21

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27

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17785433

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2169056

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