Two distinct E3 ubiquitin ligases have complementary functions in the regulation of delta and serrate signaling in Drosophila.
about
The CSL proteins, versatile transcription factors and context dependent corepressors of the notch signaling pathwayNeuralized-2 regulates a Notch ligand in cooperation with Mind bomb-1Delta-like 1-Lysine613 regulates notch signalingNotch signalling: a simple pathway becomes complexMib-Jag1-Notch signalling regulates patterning and structural roles of the notochord by controlling cell-fate decisions.An obligatory role of mind bomb-1 in notch signaling of mammalian developmentThe clathrin-binding motif and the J-domain of Drosophila Auxilin are essential for facilitating Notch ligand endocytosis.Origin and evolution of the Notch signalling pathway: an overview from eukaryotic genomes.Disruption of zebrafish cyclin G-associated kinase (GAK) function impairs the expression of Notch-dependent genes during neurogenesis and causes defects in neuronal development.Notch ligand activity is modulated by glycosphingolipid membrane composition in Drosophila melanogaster.Clinical impact of de-regulated Notch-1 and Notch-3 in the development and progression of HPV-associated different histological subtypes of precancerous and cancerous lesions of human uterine cervix.Regulation of EGFR and Notch signaling by distinct isoforms of D-cbl during Drosophila developmentMolecular genetic analyses of polytene chromosome region 72A-D in Drosophila melanogaster reveal a gene desert in 72DSequential Notch signalling at the boundary of fringe expressing and non-expressing cells.Neuralized mediates asymmetric division of neural precursors by two distinct and sequential events: promoting asymmetric localization of Numb and enhancing activation of Notch-signaling.The functions of auxilin and Rab11 in Drosophila suggest that the fundamental role of ligand endocytosis in notch signaling cells is not recycling.Endocytic regulation of notch signalling during development.Role of conserved intracellular motifs in Serrate signalling, cis-inhibition and endocytosis.New classes of mind bomb-interacting proteins identified from yeast two-hybrid screens.Notch ligand ubiquitylation: what is it good for?A tail of two sites: a bipartite mechanism for recognition of notch ligands by mind bomb E3 ligases.Structure-function analysis of delta trafficking, receptor binding and signaling in DrosophilaA re-examination of the selection of the sensory organ precursor of the bristle sensilla of Drosophila melanogaster.Distinct intracellular motifs of Delta mediate its ubiquitylation and activation by Mindbomb1 and Neuralized.Identification of the Mind Bomb1 Interaction Domain in Zebrafish DeltaD.Identification of genes that interact with Drosophila liquid facetsThe Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway.Drosophila melanogaster auxilin regulates the internalization of Delta to control activity of the Notch signaling pathway.Drosophila mind bomb2 is required for maintaining muscle integrity and survivalWhy is delta endocytosis required for effective activation of notch?Identification of the essential protein domains for Mib2 function during the development of the Drosophila larval musculature and adult flight muscles.The Notch ligand E3 ligase, Mind Bomb1, regulates glutamate receptor localization in Drosophila.A targeted in vivo RNAi screen reveals deubiquitinases as new regulators of Notch signaling.Dmon1 controls recruitment of Rab7 to maturing endosomes in Drosophila.Soluble forms of the Notch ligands Delta1 and Jagged1 promote in vivo tumorigenicity in NIH3T3 fibroblasts with distinct phenotypesNotch signaling at a glance.The E3 ubiquitin ligase mind bomb 1 ubiquitinates and promotes the degradation of survival of motor neuron protein.Mind bomb 1 in the lymphopoietic niches is essential for T and marginal zone B cell developmentDrosophila EHBP1 regulates Scabrous secretion during Notch-mediated lateral inhibition.Interaction with Notch determines endocytosis of specific Delta ligands in zebrafish neural tissue
P2860
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P2860
Two distinct E3 ubiquitin ligases have complementary functions in the regulation of delta and serrate signaling in Drosophila.
description
2005 nî lūn-bûn
@nan
2005 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մարտին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Two distinct E3 ubiquitin liga ...... errate signaling in Drosophila
@nl
Two distinct E3 ubiquitin liga ...... rrate signaling in Drosophila.
@ast
Two distinct E3 ubiquitin liga ...... rrate signaling in Drosophila.
@en
type
label
Two distinct E3 ubiquitin liga ...... errate signaling in Drosophila
@nl
Two distinct E3 ubiquitin liga ...... rrate signaling in Drosophila.
@ast
Two distinct E3 ubiquitin liga ...... rrate signaling in Drosophila.
@en
prefLabel
Two distinct E3 ubiquitin liga ...... errate signaling in Drosophila
@nl
Two distinct E3 ubiquitin liga ...... rrate signaling in Drosophila.
@ast
Two distinct E3 ubiquitin liga ...... rrate signaling in Drosophila.
@en
P2093
P2860
P3181
P1433
P1476
Two distinct E3 ubiquitin liga ...... rrate signaling in Drosophila.
@en
P2093
François Schweisguth
Sophie Hamel
Sylvie Remaud
P2860
P3181
P356
10.1371/JOURNAL.PBIO.0030096
P407
P577
2005-03-15T00:00:00Z