The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration - Wikidata - thesis-toulmin - TriplyDB

The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration

The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration

http://www.wikidata.org/entity/Q24817050

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Expression and regulation of neurotrophins in the nondegenerate and degenerate human intervertebral disc Molecular mechanisms of biological aging in intervertebral discs Disc in flames: Roles of TNF-α and IL-1β in intervertebral disc degeneration Role of cytokines in intervertebral disc degeneration: pain and disc content Expression and regulation of metalloproteinases and their inhibitors in intervertebral disc aging and degeneration Emerging technologies for molecular therapy for intervertebral disk degeneration Inflammatory cytokines induce NOTCH signaling in nucleus pulposus cells: implications in intervertebral disc degeneration MSC response to pH levels found in degenerating intervertebral discs Investigation of intervertebral disc degeneration using multivariate FTIR spectroscopic imaging Prolyl-4-hydroxylase domain protein 2 controls NF-κB/p65 transactivation and enhances the catabolic effects of inflammatory cytokines on cells of the nucleus pulposus.Intervertebral disc degeneration and ectopic bone formation in apolipoprotein E knockout mice.TNF-α and IL-1β promote a disintegrin-like and metalloprotease with thrombospondin type I motif-5-mediated aggrecan degradation through syndecan-4 in intervertebral disc Catabolic effects of endothelial cell-derived microparticles on disc cells: Implications in intervertebral disc neovascularization and degeneration.Protective role of 17β-estradiol on tumor necrosis factor-α-induced apoptosis in human nucleus pulposus cells Notochordal cell-derived therapeutic strategies for discogenic back pain.Wnt signaling activates Shh signaling in early postnatal intervertebral discs, and re-activates Shh signaling in old discs in the mouse.Orthopedic gene therapy in 2008.RANK/RANKL/OPG system in the intervertebral disc.IL-1β increases asporin expression via the NF-κB p65 pathway in nucleus pulposus cells during intervertebral disc degeneration.Muscone protects vertebral end-plate degeneration by antiinflammatory property.Advanced glycation end products regulate anabolic and catabolic activities via NLRP3-inflammasome activation in human nucleus pulposus cells.Modic changes and interleukin 1 gene locus polymorphisms in occupational cohort of middle-aged men.Proinflammatory cytokine expression profile in degenerated and herniated human intervertebral disc tissues Role of IL1A rs1800587, IL1B rs1143627 and IL1RN rs2234677 genotype regarding development of chronic lumbar radicular pain; a prospective one-year study.Tumor necrosis factor-α- and interleukin-1β-dependent matrix metalloproteinase-3 expression in nucleus pulposus cells requires cooperative signaling via syndecan 4 and mitogen-activated protein kinase-NF-κB axis: implications in inflammatory disc di Localized Intervertebral Disc Injury Leads to Organ Level Changes in Structure, Cellularity, and Biosynthesis Interleukin-17 synergizes with IFNγ or TNFα to promote inflammatory mediator release and intercellular adhesion molecule-1 (ICAM-1) expression in human intervertebral disc cells.Degenerate human nucleus pulposus cells promote neurite outgrowth in neural cells.Intradiscal transplantation of synovial mesenchymal stem cells prevents intervertebral disc degeneration through suppression of matrix metalloproteinase-related genes in nucleus pulposus cells in rabbits.Treatment outcome of chronic low back pain and radiographic lumbar disc degeneration are associated with inflammatory and matrix degrading gene variants: a prospective genetic association study.Variations in gene and protein expression in canine chondrodystrophic nucleus pulposus cells following long-term three-dimensional culture.Human mesenchymal stem cell co-culture modulates the immunological properties of human intervertebral disc tissue fragments in vitro CCL20 Secretion from the Nucleus Pulposus Improves the Recruitment of CCR6-Expressing Th17 Cells to Degenerated IVD Tissues.Genetic risk factors of disc degeneration among 12-14-year-old Danish children: a population study.Determination of annulus fibrosus cell response to tensile strain as a function of duration, magnitude, and frequency Snapshot of degenerative aging of porcine intervertebral disc: a model to unravel the molecular mechanisms.The evidence and the possible significance of autophagy in degeneration model of human cervical end-plate cartilage.Complex loading affects intervertebral disc mechanics and biology Inflammation in intervertebral disc degeneration and regeneration Imbalanced protein expression patterns of anabolic, catabolic, anti-catabolic and inflammatory cytokines in degenerative cervical disc cells: new indications for gene therapeutic treatments of cervical disc diseases

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The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration

http://www.wikidata.org/entity/Q24817050

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The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration

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The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration

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The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration

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type

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The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration

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The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration

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The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration

@nl

prefLabel

The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration

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The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration

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The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration

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Arthritis Research and Therapy

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The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration

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Anthony J Freemont

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Judith Alison Hoyland

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A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Structure and mechanism of interleukin-1 beta converting enzyme

2000 Volvo Award winner in basic science studies: Exogenous tumor necrosis factor-alpha mimics nucleus pulposus-induced neuropathology. Molecular, histologic, and behavioral comparisons in rats

Selective inhibition of tumor necrosis factor-alpha prevents nucleus pulposus-induced thrombus formation, intraneural edema, and reduction of nerve conduction velocity: possible implications for future pharmacologic treatment strategies of sciatica

Inflammatory cytokines in the herniated disc of the lumbar spine

Expression of chondrocyte markers by cells of normal and degenerate intervertebral discs

Dedifferentiated chondrocytes cultured in alginate beads: restoration of the differentiated phenotype and of the metabolic responses to interleukin-1beta.

The human lumbar intervertebral disc: evidence for changes in the biosynthesis and denaturation of the extracellular matrix with growth, maturation, ageing, and degeneration.

Current understanding of cellular and molecular events in intervertebral disc degeneration: implications for therapy.

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