about
The Drug Discovery and Development Industry in India-Two Decades of Proprietary Small-Molecule R&D.Cyclic Boronates Inhibit All Classes of β-Lactamases.Activity of ceftolozane/tazobactam against surveillance and 'problem' Enterobacteriaceae, Pseudomonas aeruginosa and non-fermenters from the British Isles.ETX2514 is a broad-spectrum β-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii.In Vitro Activity of Aztreonam-Avibactam against Enterobacteriaceae and Pseudomonas aeruginosa Isolated by Clinical Laboratories in 40 Countries from 2012 to 2015.Total Synthesis of Aspergillomarasmine A and Related Compounds: A Sulfamidate Approach Enables Exploration of Structure-Activity Relationships.What is the role of the new β-lactam/β-lactamase inhibitors ceftolozane/tazobactam and ceftazidime/avibactam?Reversible inactivation of a peptidoglycan transpeptidase by a β-lactam antibiotic mediated by β-lactam-ring recyclization in the enzyme active site.Comparison of Etest to Broth Microdilution for Testing of Susceptibility of Pseudomonas aeruginosa to Ceftolozane-Tazobactam.The Challenge of Overcoming Antibiotic Resistance: An Adjuvant Approach?Triple combination antibiotic therapy for carbapenemase-producing Klebsiella pneumoniae: a systematic review.The frequency and mechanism of spontaneous resistance to sulbactam combined with the novel β-lactamase inhibitor ETX2514 in clinical isolates of Acinetobacter baumannii.Carbapenemase-Producing Organisms: A Global Scourge!Probing the Interaction of Aspergillomarasmine A with Metallo-β-lactamases NDM-1, VIM-2, and IMP-7.Potent β-Lactam Enhancer Activity of Zidebactam and WCK 5153 against Acinetobacter baumannii, Including Carbapenemase-Producing Clinical Isolates.Probing the Mechanism of Inactivation of the FOX-4 Cephamycinase by Avibactam.Potential of high-dose cefepime/tazobactam against multiresistant Gram-negative pathogens.The Continuing Challenge of Metallo-β-Lactamase Inhibition: Mechanism Matters.Exploring Additional Dimensions of Complexity in Inhibitor Design for Serine β-Lactamases: Mechanistic and Intra- and Inter-molecular Chemistry Approaches.Impaired Inhibition by Avibactam and Resistance to the Ceftazidime-Avibactam Combination Due to the D179Y Substitution in the KPC-2 β-Lactamase.The Infinity War: How to Cope with Carbapenem-resistant
P2860
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P2860
description
2016 nî lūn-bûn
@nan
2016 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
New β-Lactamase Inhibitors in the Clinic
@ast
New β-Lactamase Inhibitors in the Clinic
@en
New β-Lactamase Inhibitors in the Clinic
@nl
type
label
New β-Lactamase Inhibitors in the Clinic
@ast
New β-Lactamase Inhibitors in the Clinic
@en
New β-Lactamase Inhibitors in the Clinic
@nl
prefLabel
New β-Lactamase Inhibitors in the Clinic
@ast
New β-Lactamase Inhibitors in the Clinic
@en
New β-Lactamase Inhibitors in the Clinic
@nl
P2860
P1476
New β-Lactamase Inhibitors in the Clinic
@en
P2860
P304
P356
10.1016/J.IDC.2016.02.007
P407
P577
2016-06-01T00:00:00Z