Molecular landscape of pancreatic cancer: implications for current clinical trials - Wikidata - thesis-toulmin - TriplyDB

Molecular landscape of pancreatic cancer: implications for current clinical trials

Molecular landscape of pancreatic cancer: implications for current clinical trials

http://www.wikidata.org/entity/Q26824528

about

Vaccines, Adjuvants, and Dendritic Cell Activators--Current Status and Future Challenges.Pancreatic Cancer, A Mis-interpreter of the Epigenetic Language PIK3CA mutations can initiate pancreatic tumorigenesis and are targetable with PI3K inhibitors Molecular profiling of a case of advanced pancreatic cancer identifies an active and tolerable combination of targeted therapy with backbone chemotherapy.The prognostic role of desmoplastic stroma in pancreatic ductal adenocarcinoma Serum CA125 is a novel predictive marker for pancreatic cancer metastasis and correlates with the metastasis-associated burden.The effects of curcumin (diferuloylmethane) on body composition of patients with advanced pancreatic cancer.Rottlerin exhibits anti-cancer effect through inactivation of S phase kinase-associated protein 2 in pancreatic cancer cells.Periostin promotes tumor angiogenesis in pancreatic cancer via Erk/VEGF signaling Prognostic value, localization and correlation of PD-1/PD-L1, CD8 and FOXP3 with the desmoplastic stroma in pancreatic ductal adenocarcinoma.Generation and molecular characterization of pancreatic cancer patient-derived xenografts reveals their heterologous nature.Prognostic role and correlation of CA9, CD31, CD68 and CD20 with the desmoplastic stroma in pancreatic ductal adenocarcinoma.Targeted next generation sequencing of endoscopic ultrasound acquired cytology from ampullary and pancreatic adenocarcinoma has the potential to aid patient stratification for optimal therapy selection.Novel p21-Activated Kinase 4 (PAK4) Allosteric Modulators Overcome Drug Resistance and Stemness in Pancreatic Ductal Adenocarcinoma.K-Ras4B/calmodulin/PI3Kα: A promising new adenocarcinoma-specific drug target?Analysis of ctDNA to predict prognosis and monitor treatment responses in metastatic pancreatic cancer patients.Molecular subtype specific efficacy of MEK inhibitors in pancreatic cancers Individualized drug screening based on next generation sequencing and patient derived xenograft model for pancreatic cancer with bone metastasis.Genetics of pancreatic cancer and implications for therapy.The lncRNA-HOXA-AS2/EZH2/LSD1 oncogene complex promotes cell proliferation in pancreatic cancer.Comprehensive genomic profiling of extrahepatic cholangiocarcinoma reveals a long tail of therapeutic targets.Increased KIF4A expression is a potential prognostic factor in prostate cancer.Pancreatic Cancer: Molecular Characterization, Clonal Evolution and Cancer Stem Cells.

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P2860

Molecular landscape of pancreatic cancer: implications for current clinical trials

http://www.wikidata.org/entity/Q26824528

description

2015 nî lūn-bûn

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2015 թուականի Մարտին հրատարակուած գիտական յօդուած

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2015 թվականի մարտին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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Molecular landscape of pancreatic cancer: implications for current clinical trials

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Molecular landscape of pancreatic cancer: implications for current clinical trials

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Molecular landscape of pancreatic cancer: implications for current clinical trials

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Molecular landscape of pancreatic cancer: implications for current clinical trials

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Molecular landscape of pancreatic cancer: implications for current clinical trials

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Molecular landscape of pancreatic cancer: implications for current clinical trials

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Molecular landscape of pancreatic cancer: implications for current clinical trials

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Molecular landscape of pancreatic cancer: implications for current clinical trials

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Molecular landscape of pancreatic cancer: implications for current clinical trials

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Molecular landscape of pancreatic cancer: implications for current clinical trials

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Gregory M. Heestand

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Creative Commons Attribution 2.5 Unported

P2860

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

The Catalogue of Somatic Mutations in Cancer (COSMIC)

Hypo-phosphorylation of the retinoblastoma protein (pRb) by cyclin D:Cdk4/6 complexes results in active pRb

Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene

MDM2 small-molecule antagonist RG7112 activates p53 signaling and regresses human tumors in preclinical cancer models

DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer.

Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers.

SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer.

Personalizing cancer treatment in the age of global genomic analyses: PALB2 gene mutations and the response to DNA damaging agents in pancreatic cancer.

Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial.

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4553-61

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10.18632/ONCOTARGET.2972

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Razelle Kurzrock

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2015-03-10T00:00:00Z

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272839929

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pancreatic cancer

tumor biomarkers

biomedical investigative technique

pancreatic neoplasm

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4467098

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