Cryo-electron microscopy structure of the TRPV2 ion channel - Wikidata - thesis-toulmin - TriplyDB

Cryo-electron microscopy structure of the TRPV2 ion channel

Cryo-electron microscopy structure of the TRPV2 ion channel

http://www.wikidata.org/entity/Q27310168

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TRPV1: A Target for Rational Drug Design The Use of Multiscale Molecular Simulations in Understanding a Relationship between the Structure and Function of Biological Systems of the Brain: The Application to Monoamine Oxidase Enzymes Structure of the full-length TRPV2 channel by cryo-EM.TRP Channels in Skin Biology and Pathophysiology Crystal structure of the epithelial calcium channel TRPV6 Engineering vanilloid-sensitivity into the rat TRPV2 channel Function and regulation of TRPP2 ion channel revealed by a gain-of-function mutant The First Extracellular Linker Is Important for Several Aspects of the Gating Mechanism of Human TRPA1 Channel.The S1 helix critically regulates the finely tuned gating of Kv11.1 channels TRPV1 temperature activation is specifically sensitive to strong decreases in amino acid hydrophobicity.Rational design and validation of a vanilloid-sensitive TRPV2 ion channel A competing hydrophobic tug on L596 to the membrane core unlatches S4-S5 linker elbow from TRP helix and allows TRPV4 channel to open.Understand spiciness: mechanism of TRPV1 channel activation by capsaicin IonchanPred 2.0: A Tool to Predict Ion Channels and Their Types.Structure of IP3R channel: high-resolution insights from cryo-EM.Toward elucidating the heat activation mechanism of the TRPV1 channel gating by molecular dynamics simulation.Electron Cryo-microscopy as a Tool for Structure-Based Drug Development.Side chain flexibility and coupling between the S4-S5 linker and the TRP domain in thermo-sensitive TRP channels: Insights from protein modeling.Expression, purification, and contaminant detection for structural studies of Ralstonia metallidurance ClC protein rm1.Tyrosine Residues from the S4-S5 Linker of Kv11.1 Channels Are Critical for Slow Deactivation Energetics of Ion Permeation in an Open-Activated TRPV1 Channel.Electron cryo-microscopy structure of the mechanotransduction channel NOMPC.The Structure of the Polycystic Kidney Disease Channel PKD2 in Lipid Nanodiscs.[Cryo-microscopy, an alternative to the X-ray crystallography?].Structural determinants of 5',6'-epoxyeicosatrienoic acid binding to and activation of TRPV4 channel.Swapping of transmembrane domains in the epithelial calcium channel TRPV6.A Gate Hinge Controls the Epithelial Calcium Channel TRPV5.Regulation of TRPP3 Channel Function by N-terminal Domain Palmitoylation and Phosphorylation.TRPC Channel Structure and Properties.Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3.Human TRPML1 channel structures in open and closed conformations.Decrypting the Heat Activation Mechanism of TRPV1 Channel by Molecular Dynamics Simulation.Lipid environment of membrane proteins in cryo-EM based structural analysis.Shared CaM- and S100A1-binding epitopes in the distal TRPM4 N terminus.A binding-block ion selective mechanism revealed by a Na/K selective channel.TRPM5 in the battle against diabetes and obesity.Never at rest: insights into the conformational dynamics of ion channels from cryo-electron microscopy.Structure of the cold- and menthol-sensing ion channel TRPM8.Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM.Targeting nociceptive transient receptor potential channels to treat chronic pain: current state of the field.

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Cryo-electron microscopy structure of the TRPV2 ion channel

http://www.wikidata.org/entity/Q27310168

description

2016 nî lūn-bûn

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2016 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2016 թվականի փետրվարին հրատարակված գիտական հոդված

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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name

Cryo-electron microscopy structure of the TRPV2 ion channel

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Cryo-electron microscopy structure of the TRPV2 ion channel

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Cryo-electron microscopy structure of the TRPV2 ion channel

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type

label

Cryo-electron microscopy structure of the TRPV2 ion channel

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Cryo-electron microscopy structure of the TRPV2 ion channel

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Cryo-electron microscopy structure of the TRPV2 ion channel

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Cryo-electron microscopy structure of the TRPV2 ion channel

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Cryo-electron microscopy structure of the TRPV2 ion channel

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Cryo-electron microscopy structure of the TRPV2 ion channel

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Nature Structural & Molecular Biology

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Cryo-electron microscopy structure of the TRPV2 ion channel

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Ben C Chung

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Lejla Zubcevic

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Seok-Yong Lee

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Zhirui Liu

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P2860

A capsaicin-receptor homologue with a high threshold for noxious heat

The ankyrin repeats of TRPV1 bind multiple ligands and modulate channel sensitivity

The capsaicin receptor: a heat-activated ion channel in the pain pathway

Evolutionary origin of a secondary structure: π-helices as cryptic but widespread insertional variations of α-helices that enhance protein functionality

PHENIX: a comprehensive Python-based system for macromolecular structure solution

Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment

Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM.

Structural basis for Ca2+ selectivity of a voltage-gated calcium channel

Structure of the TRPV1 ion channel determined by electron cryo-microscopy

TRPV1 structures in distinct conformations reveal activation mechanisms

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180-186

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1666126

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10.1038/NSMB.3159

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2

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23

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Gabriel C. Lander

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2016-02-01T00:00:00Z

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290992866

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1027734578

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26779611

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cryogenic electron microscopy

structural biology

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4876856

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