about
Mechanism of allosteric propagation across a β-sheet structure investigated by molecular dynamics simulations.Evolutionary fine-tuning of conformational ensembles in FimH during host-pathogen interactions.Plasma fibronectin stabilizes Borrelia burgdorferi-endothelial interactions under vascular shear stress by a catch-bond mechanismMechanical forces regulate the reactivity of a thioester bond in a bacterial adhesinBioadhesive Bacterial Microswimmers for Targeted Drug Delivery in the Urinary and Gastrointestinal Tracts.Differentiation of Crohn's Disease-Associated Isolates from Other Pathogenic Escherichia coli by Fimbrial Adhesion under Shear Force.The Escherichia coli P and Type 1 Pilus Assembly Chaperones PapD and FimC Are Monomeric in Solution.The potential of FimH as a novel therapeutic target for the treatment of Crohn's disease.Catch Bonds at T Cell Interfaces: Impact of Surface Reorganization and Membrane Fluctuations.Target-directed Dynamic Combinatorial Chemistry: A Study on Potentials and Pitfalls as Exemplified on a Bacterial Target.Rational design strategies for FimH antagonists: new drugs on the horizon for urinary tract infection and Crohn's disease.UroPathogenic Escherichia coli (UPEC) Infections: Virulence Factors, Bladder Responses, Antibiotic, and Non-antibiotic Antimicrobial Strategies.The Conformational Variability of FimH: Which Conformation Represents the Therapeutic Target?What contributes to an effective mannose recognition domain?Conformational Switch of the Bacterial Adhesin FimH in the Absence of the Regulatory Domain - Engineering a Minimalistic Allosteric System.Amyloid-Like β-Aggregates as Force-Sensitive Switches in Fungal Biofilms and Infections.Structural basis of nanobody-mediated blocking of BtuF, the cognate substrate-binding protein of the Escherichia coli vitamin B12 transporter BtuCD.The price of flexibility - a case study on septanoses as pyranose mimetics.Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection.Cell behavior of the highly sticky bacterium Acinetobacter sp. Tol 5 during adhesion in laminar flows.Staphylococcus aureus clumping factor A is a force-sensitive molecular switch that activates bacterial adhesion.2D transition metal dichalcogenides with glucan multivalency for antibody-free pathogen recognition.The Role of Glycans in Bacterial Adhesion to Mucosal Surfaces: How Can Single-Molecule Techniques Advance Our Understanding?Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding
P2860
Q30387043-70703D29-5AFA-4FE4-BB6E-5250EA11D5A0Q30838228-07A186C1-6B26-41D5-925C-B78450033FCAQ30847374-0C73F5FD-8AFF-4EF6-A1F5-37C2C8BB9CA4Q33737728-41FF3684-048A-409C-A106-39FD96146360Q33806268-6E63DDAD-CA5E-4958-8DC8-820503E7FC0DQ37057409-4DCCEBDC-5B43-4AD3-BF86-AF1FFA8E030DQ37174241-1459982B-F6C4-4423-B529-83582748137CQ38648792-C8A88C37-77A6-447B-A6EA-64F84706A365Q38682295-11861CCF-0217-4BB3-976F-F2034ECADAF9Q38706795-FB73629C-909D-4946-845E-F16B326B885FQ39307431-ED7BE58A-6D06-4155-BCB1-F1C3CB2BB701Q40071513-4C5D650D-14C5-41EB-A13B-98F756723617Q40749888-D5139279-E6BA-4E45-AD94-05A2DA3FC6C6Q47097147-F37DDD6A-608C-4F45-ACFC-F2D70CAFC166Q47309457-3500CF13-7C7E-45B0-AFFF-C285BB5D535DQ47350221-9BC4E889-1800-4809-B96D-33A009C63050Q47586490-9DF0D666-DA81-420F-B831-F420FFD77B4DQ52599567-1F3E13AF-86F2-4919-B129-92D9421B76A0Q53704435-967313BB-59FE-4980-8FC2-0275171DAF40Q55007049-EF07D22D-EF2F-40C1-99DB-4DF8465F1A23Q55190909-E189994F-98E1-4146-9F55-56FBF33FD05EQ55439430-2F623218-2590-4468-B165-C7BBCE2C3FE7Q56888631-CA32508E-41C5-4365-A270-37E8A3AE7B7FQ57310383-968E9E98-2892-40F8-8159-97AEB99EC41E
P2860
description
2016 nî lūn-bûn
@nan
2016 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի մարտին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Catch-bond mechanism of the bacterial adhesin FimH
@nl
Catch-bond mechanism of the bacterial adhesin FimH.
@ast
Catch-bond mechanism of the bacterial adhesin FimH.
@en
type
label
Catch-bond mechanism of the bacterial adhesin FimH
@nl
Catch-bond mechanism of the bacterial adhesin FimH.
@ast
Catch-bond mechanism of the bacterial adhesin FimH.
@en
prefLabel
Catch-bond mechanism of the bacterial adhesin FimH
@nl
Catch-bond mechanism of the bacterial adhesin FimH.
@ast
Catch-bond mechanism of the bacterial adhesin FimH.
@en
P2093
P2860
P3181
P356
P1476
Catch-bond mechanism of the bacterial adhesin FimH.
@en
P2093
Beat Ernst
Deniz Eriş
Giulio Navarra
Jonathan Eras
Maximilian M Sauer
Roman P Jakob
Rudi Glockshuber
Sefer Baday
Simon Bernèche
Timm Maier
P2860
P2888
P3181
P356
10.1038/NCOMMS10738
P407
P577
2016-03-07T00:00:00Z
P5875
P6179
1030988095