Irvalec inserts into the plasma membrane causing rapid loss of integrity and necrotic cell death in tumor cells

Irvalec inserts into the plasma membrane causing rapid loss of integrity and necrotic cell death in tumor cells

Item
http://www.wikidata.org/entity/Q27346446
Elisidepsin Interacts Directly with Glycosylceramides in the Plasma Membrane of Tumor Cells to Induce Necrotic Cell DeathA small molecule with anticancer and antimetastatic activities induces rapid mitochondrial-associated necrosis in breast cancer.Epithelial-mesenchymal transition markers and HER3 expression are predictors of elisidepsin treatment response in breast and pancreatic cancer cell linesPhase I study of elisidepsin (Irvalec®) in combination with carboplatin or gemcitabine in patients with advanced malignancies.Peptides, Peptidomimetics, and Polypeptides from Marine Sources: A Wealth of Natural Sources for Pharmaceutical Applications.Co-cultivation--a powerful emerging tool for enhancing the chemical diversity of microorganismsPredictive factors of sensitivity to elisidepsin, a novel Kahalalide F-derived marine compoundHypoxia reduces the efficiency of elisidepsin by inhibiting hydroxylation and altering the structure of lipid raftsThe first total synthesis of the cyclodepsipeptide pipecolidepsin A.Phase Ib/II study of elisidepsin in metastatic or advanced gastroesophageal cancer (IMAGE trial).Phase I, dose-escalating study of elisidepsin (Irvalec(®)), a plasma membrane-disrupting marine antitumor agent, in combination with erlotinib in patients with advanced malignant solid tumors.A phase I and pharmacokinetic study of elisidepsin (PM02734) in patients with advanced solid tumors.
P2860

Irvalec inserts into the plasma membrane causing rapid loss of integrity and necrotic cell death in tumor cells

Item
http://www.wikidata.org/entity/Q27346446
description
2011 nî lūn-bûn
@nan
2011 թուականին հրատարակուած գիտական յօդուած
@hyw
2011 թվականին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Irvalec inserts into the plasm ...... otic cell death in tumor cells
@ast
Irvalec inserts into the plasm ...... otic cell death in tumor cells
@en
Irvalec inserts into the plasm ...... otic cell death in tumor cells
@nl
type
label
Irvalec inserts into the plasm ...... otic cell death in tumor cells
@ast
Irvalec inserts into the plasm ...... otic cell death in tumor cells
@en
Irvalec inserts into the plasm ...... otic cell death in tumor cells
@nl
prefLabel
Irvalec inserts into the plasm ...... otic cell death in tumor cells
@ast
Irvalec inserts into the plasm ...... otic cell death in tumor cells
@en
Irvalec inserts into the plasm ...... otic cell death in tumor cells
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
Irvalec inserts into the plasm ...... otic cell death in tumor cells
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0019042
P407
P433
P478
P50
P577
P5875
P698
P932