Structure of the DNA repair enzyme endonuclease IV and its DNA complex: double-nucleotide flipping at abasic sites and three-metal-ion catalysis
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Isolation of a small molecule inhibitor of DNA base excision repair.Structure-based function prediction of uncharacterized protein using binding sites comparisonDNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]Solution structure of an oligonucleotide containing an abasic site: evidence for an unusual deoxyribose conformationCrystal structure ofBacillus subtilis ioli shows endonuclase IV fold with altered Zn bindingMetal ions and phosphate binding in the H-N-H motif: Crystal structures of the nuclease domain of ColE7/Im7 in complex with a phosphate ion and different divalent metal ionsSynthesis, characterization and solution structure of tethered oligonucleotides containing an internal 3'-phosphoglycolate, 5'-phosphate gapped lesionDNA oligonucleotides with A, T, G or C opposite an abasic site: structure and dynamicsDNA apurinic-apyrimidinic site binding and excision by endonuclease IVStructure of L-Xylulose-5-Phosphate 3-Epimerase (UlaE) from the Anaerobic L-Ascorbate Utilization Pathway of Escherichia coli: Identification of a Novel Phosphate Binding Motif within a TIM Barrel FoldInvolvement of a carboxylated lysine in UV damage endonucleaseStructure of the endonuclease IV homologue fromThermotoga maritimain the presence of active-site divalent metal ionsCrystal structure of a metal-dependent phosphoesterase (YP_910028.1) from Bifidobacterium adolescentis: Computational prediction and experimental validation of phosphoesterase activityUV damage endonuclease employs a novel dual-dinucleotide flipping mechanism to recognize different DNA lesionsConserved Structural Chemistry for Incision Activity in Structurally Non-homologous Apurinic/Apyrimidinic Endonuclease APE1 and Endonuclease IV DNA Repair EnzymesDNA Sequence Context Conceals α-Anomeric LesionsInsight into mechanisms of 3'-5' exonuclease activity and removal of bulky 8,5'-cyclopurine adducts by apurinic/apyrimidinic endonucleasesStructure ofD-tagatose 3-epimerase-like protein fromMethanocaldococcus jannaschiiHydroxyurea induces site-specific DNA damage via formation of hydrogen peroxide and nitric oxideEnhanced activity of adenine-DNA glycosylase (Myh) by apurinic/apyrimidinic endonuclease (Ape1) in mammalian base excision repair of an A/GO mismatchUsing electrostatic potentials to predict DNA-binding sites on DNA-binding proteins.Accelerated Molecular Dynamics Simulations with the AMOEBA Polarizable Force Field on Graphics Processing UnitsUsing surface-bound rubidium ions for protein phasing.Purification, crystallization and preliminary crystallographic analysis of a thermostable endonuclease IV from Thermotoga maritima.The zinc ion in the HNH motif of the endonuclease domain of colicin E7 is not required for DNA binding but is essential for DNA hydrolysis.Biological properties of single chemical-DNA adducts: a twenty year perspectiveHigh efficiency detection of bi-stranded abasic clusters in gamma-irradiated DNA by putrescineAdoMet-dependent methylation, DNA methyltransferases and base flipping.The structural basis of damaged DNA recognition and endonucleolytic cleavage for very short patch repair endonuclease.DNA-Destabilizing Agents as an Alternative Approach for Targeting DNA: Mechanisms of Action and Cellular ConsequencesRole of the Nfo (YqfS) and ExoA apurinic/apyrimidinic endonucleases in protecting Bacillus subtilis spores from DNA damageStructure and function of TatD exonuclease in DNA repair.Base excision repair in a network of defence and tolerance.Targeted deletion of mNth1 reveals a novel DNA repair enzyme activity.Intrinsic apurinic/apyrimidinic (AP) endonuclease activity enables Bacillus subtilis DNA polymerase X to recognize, incise, and further repair abasic sites.Calcium inhibition of ribonuclease H1 two-metal ion catalysisFormation and repair of tobacco carcinogen-derived bulky DNA adductsUncoupling of the base excision and nucleotide incision repair pathways reveals their respective biological roles.Forespore-specific expression of Bacillus subtilis yqfS, which encodes type IV apurinic/apyrimidinic endonuclease, a component of the base excision repair pathway.Development and evaluation of human AP endonuclease inhibitors in melanoma and glioma cell lines
P2860
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P2860
Structure of the DNA repair enzyme endonuclease IV and its DNA complex: double-nucleotide flipping at abasic sites and three-metal-ion catalysis
description
1999 nî lūn-bûn
@nan
1999 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Structure of the DNA repair en ...... and three-metal-ion catalysis
@ast
Structure of the DNA repair en ...... and three-metal-ion catalysis
@en
Structure of the DNA repair en ...... and three-metal-ion catalysis
@nl
type
label
Structure of the DNA repair en ...... and three-metal-ion catalysis
@ast
Structure of the DNA repair en ...... and three-metal-ion catalysis
@en
Structure of the DNA repair en ...... and three-metal-ion catalysis
@nl
prefLabel
Structure of the DNA repair en ...... and three-metal-ion catalysis
@ast
Structure of the DNA repair en ...... and three-metal-ion catalysis
@en
Structure of the DNA repair en ...... and three-metal-ion catalysis
@nl
P2093
P3181
P1433
P1476
Structure of the DNA repair en ...... and three-metal-ion catalysis
@en
P2093
D J Hosfield
J A Tainer
R P Cunningham
P304
P3181
P356
10.1016/S0092-8674(00)81968-6
P407
P577
1999-08-06T00:00:00Z