Crystal structure of the cytosolic C2A-C2B domains of synaptotagmin III. Implications for Ca(+2)-independent snare complex interaction
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Synaptotagmin gene content of the sequenced genomesStructure and Ca²⁺-binding properties of the tandem C₂ domains of E-Syt2Rapid model building of alpha-helices in electron-density mapsDOC2B acts as a calcium switch and enhances vesicle fusionThe Exocytosis-regulatory protein synaptotagmin VII mediates cell invasion by Trypanosoma cruziCalcium control of neurotransmitter releaseSynaptotagmins form a hierarchy of exocytotic Ca(2+) sensors with distinct Ca(2+) affinitiesDistinct initial SNARE configurations underlying the diversity of exocytosisHigh resolution structure, stability, and synaptotagmin binding of a truncated neuronal SNARE complexStructure of human synaptotagmin 1 C2AB in the absence of Ca2+ reveals a novel domain associationMolecular mechanism of the synaptotagmin–SNARE interaction in Ca2+-triggered vesicle fusionTowards automated crystallographic structure refinement with phenix.refineQuantitation of the calcium and membrane binding properties of the C2 domains of dysferlinReconstituted syntaxin1a/SNAP25 interacts with negatively charged lipids as measured by lateral diffusion in planar supported bilayers.Analysis of the synaptotagmin family during reconstituted membrane fusion. Uncovering a class of inhibitory isoformsCrystallographic identification of Ca2+ and Sr2+ coordination sites in synaptotagmin I C2B domainC2 domains of protein kinase C isoforms alpha, beta, and gamma: activation parameters and calcium stoichiometries of the membrane-bound stateDecision-making in structure solution using Bayesian estimates of map quality: the PHENIX AutoSol wizardCloning, expression, purification, crystallization and preliminary X-ray diffraction crystallographic study of human synaptotagmin 5 C2A domainA manual collection of Syt, Esyt, Rph3a, Rph3al, Doc2, and Dblc2 genes from 46 metazoan genomes--an open access resource for neuroscience and evolutionary biology.High metal concentrations are required for self-association of synaptotagmin II.Pulling force generated by interacting SNAREs facilitates membrane hemifusion.Investigation of SNARE-Mediated Membrane Fusion Mechanism Using Atomic Force Microscopy.Vesicular reuptake inhibition by a synaptotagmin I C2B domain antibody at the squid giant synapse.Rapid model building of beta-sheets in electron-density mapsRapid chain tracing of polypeptide backbones in electron-density mapsSingle-molecule studies of the neuronal SNARE fusion machinery.Three distinct kinetic groupings of the synaptotagmin family: candidate sensors for rapid and delayed exocytosis.Synaptotagmin I is a molecular target for lead.C2A activates a cryptic Ca(2+)-triggered membrane penetration activity within the C2B domain of synaptotagmin I.Linker mutations reveal the complexity of synaptotagmin 1 action during synaptic transmission.Single-molecule FRET-derived model of the synaptotagmin 1-SNARE fusion complex.Molecular structures of proteins involved in vesicle fusion.Functional and physical coupling of voltage-sensitive calcium channels with exocytotic proteins: ramifications for the secretion mechanism.Synaptotagmin interaction with the syntaxin/SNAP-25 dimer is mediated by an evolutionarily conserved motif and is sensitive to inositol hexakisphosphate.Single-molecule studies of synaptotagmin and complexin binding to the SNARE complex.Perforin-mediated target-cell death and immune homeostasis.Role of synaptotagmin in Ca2+-triggered exocytosis.Tag team action at the synapse.Visualization of synaptotagmin I oligomers assembled onto lipid monolayers.
P2860
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P2860
Crystal structure of the cytosolic C2A-C2B domains of synaptotagmin III. Implications for Ca(+2)-independent snare complex interaction
description
1999 nî lūn-bûn
@nan
1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Crystal structure of the cytos ...... dent snare complex interaction
@ast
Crystal structure of the cytos ...... dent snare complex interaction
@en
Crystal structure of the cytos ...... dent snare complex interaction
@nl
type
label
Crystal structure of the cytos ...... dent snare complex interaction
@ast
Crystal structure of the cytos ...... dent snare complex interaction
@en
Crystal structure of the cytos ...... dent snare complex interaction
@nl
prefLabel
Crystal structure of the cytos ...... dent snare complex interaction
@ast
Crystal structure of the cytos ...... dent snare complex interaction
@en
Crystal structure of the cytos ...... dent snare complex interaction
@nl
P2860
P3181
P356
P1476
Crystal structure of the cytos ...... dent snare complex interaction
@en
P2093
P2860
P304
P3181
P356
10.1083/JCB.147.3.589
P407
P577
1999-11-01T00:00:00Z