Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs
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Novel conserved domains in proteins with predicted roles in eukaryotic cell-cycle regulation, decapping and RNA stabilitySm and Sm-like proteins assemble in two related complexes of deep evolutionary origin.Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like proteinPurification and characterization of native spliceosomes suitable for three-dimensional structural analysis.Structure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesisGemin8 is a novel component of the survival motor neuron complex and functions in small nuclear ribonucleoprotein assemblyGemin8 is required for the architecture and function of the survival motor neuron complexFunctional organization of the Sm core in the crystal structure of human U1 snRNPToward an assembly line for U7 snRNPs: interactions of U7-specific Lsm proteins with PRMT5 and SMN complexesStructure of a key intermediate of the SMN complex reveals Gemin2's crucial function in snRNP assemblyUnique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processingThe splicing regulator TIA-1 interacts with U1-C to promote U1 snRNP recruitment to 5' splice sites.Herpes simplex virus IE63 (ICP27) protein interacts with spliceosome-associated protein 145 and inhibits splicing prior to the first catalytic stepRNA binding in an Sm core domain: X-ray structure and functional analysis of an archaeal Sm protein complex.Interaction between the small-nuclear-RNA cap hypermethylase and the spinal muscular atrophy protein, survival of motor neuronStructures of the pleiotropic translational regulator Hfq and an Hfq-RNA complex: a bacterial Sm-like proteinSymplekin and multiple other polyadenylation factors participate in 3'-end maturation of histone mRNAsProteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.Predicted structure and phyletic distribution of the RNA-binding protein Hfq.Characterization of U6 snRNA-protein interactions.Symmetrical dimethylation of arginine residues in spliceosomal Sm protein B/B' and the Sm-like protein LSm4, and their interaction with the SMN protein.The 5' and 3' domains of yeast U6 snRNA: Lsm proteins facilitate binding of Prp24 protein to the U6 telestem regionThe human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrnl in distinct cytoplasmic foci.Sm protein-Sm site RNA interactions within the inner ring of the spliceosomal snRNP core structure.The methylosome, a 20S complex containing JBP1 and pICln, produces dimethylarginine-modified Sm proteinsThe Sm domain is an ancient RNA-binding motif with oligo(U) specificityA Sm-like protein complex that participates in mRNA degradationThe oligomerization and ligand-binding properties of Sm-like archaeal proteins (SmAPs)Structure of yeast U6 snRNPs: arrangement of Prp24p and the LSm complex as revealed by electron microscopyThe Drosophila U7 snRNP proteins Lsm10 and Lsm11 are required for histone pre-mRNA processing and play an essential role in developmentA divergent Sm fold in EDC3 proteins mediates DCP1 binding and P-body targetingMost nuclear systemic autoantigens are extremely disordered proteins: implications for the etiology of systemic autoimmunityA stochastic view of spliceosome assembly and recycling in the nucleusThe crystal structure of a heptameric archaeal Sm protein: Implications for the eukaryotic snRNP coreCrystal structures of the Pyrococcus abyssi Sm core and its complex with RNA. Common features of RNA binding in archaea and eukaryaHomomeric ring assemblies of eukaryotic Sm proteins have affinity for both RNA and DNA. Crystal structure of an oligomeric complex of yeast SmFStructure and assembly of an augmented Sm-like archaeal protein 14-merSm-like proteins in Eubacteria: the crystal structure of the Hfq protein from Escherichia coliAn Hfq-like protein in archaea: Crystal structure and functional characterization of the Sm protein from Methanococcus jannaschiiStructure of yeast Dom34: a protein related to translation termination factor Erf1 and involved in No-Go decay
P2860
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P2860
Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs
description
1999 nî lūn-bûn
@nan
1999 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Crystal structures of two Sm p ...... bly of the spliceosomal snRNPs
@ast
Crystal structures of two Sm p ...... bly of the spliceosomal snRNPs
@en
Crystal structures of two Sm p ...... bly of the spliceosomal snRNPs
@nl
type
label
Crystal structures of two Sm p ...... bly of the spliceosomal snRNPs
@ast
Crystal structures of two Sm p ...... bly of the spliceosomal snRNPs
@en
Crystal structures of two Sm p ...... bly of the spliceosomal snRNPs
@nl
prefLabel
Crystal structures of two Sm p ...... bly of the spliceosomal snRNPs
@ast
Crystal structures of two Sm p ...... bly of the spliceosomal snRNPs
@en
Crystal structures of two Sm p ...... bly of the spliceosomal snRNPs
@nl
P2093
P921
P1433
P1476
Crystal structures of two Sm p ...... bly of the spliceosomal snRNPs
@en
P2093
E de la Fortelle
R Lührmann
P304
P356
10.1016/S0092-8674(00)80550-4
P407
P577
1999-02-05T00:00:00Z