Insights into the ubiquitin transfer cascade from the structure of the activating enzyme for NEDD8 - Wikidata - thesis-toulmin - TriplyDB

Insights into the ubiquitin transfer cascade from the structure of the activating enzyme for NEDD8

Insights into the ubiquitin transfer cascade from the structure of the activating enzyme for NEDD8

http://www.wikidata.org/entity/Q27640736

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Conservation in the mechanism of Nedd8 activation by the human AppBp1-Uba3 heterodimer A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8 E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification A novel protein-conjugating system for Ufm1, a ubiquitin-fold modifier Structures of the SUMO E1 provide mechanistic insights into SUMO activation and E2 recruitment to E1 Single-nucleotide polymorphisms in NAGNAG acceptors are highly predictive for variations of alternative splicing.Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways Basis for a ubiquitin-like protein thioester switch toggling E1–E2 affinity Structure of a SUMO-binding-motif Mimic Bound to Smt3p–Ubc9p: Conservation of a Non-covalent Ubiquitin-like Protein–E2 Complex as a Platform for Selective Interactions within a SUMO Pathway The Intrinsic Affinity between E2 and the Cys Domain of E1 in Ubiquitin-like Modifications Structural Dissection of a Gating Mechanism Preventing Misactivation of Ubiquitin by NEDD8’s E1 † ‡How the MccB bacterial ancestor of ubiquitin E1 initiates biosynthesis of the microcin C7 antibiotic Crystal Structure of the Human Ubiquitin-activating Enzyme 5 (UBA5) Bound to ATP: MECHANISTIC INSIGHTS INTO A MINIMALISTIC E1 ENZYME Crystal Structure of UBA2ufd-Ubc9: Insights into E1-E2 Interactions in Sumo Pathways N-Terminal Acetylation Acts as an Avidity Enhancer Within an Interconnected Multiprotein Complex Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7–Atg3 and Atg7–Atg10 structures Atg8 Transfer from Atg7 to Atg3: A Distinctive E1-E2 Architecture and Mechanism in the Autophagy Pathway Structure of a Ubiquitin E1-E2 Complex: Insights to E1-E2 Thioester Transfer E2-binding surface on Uba3 β-grasp domain undergoes a conformational transition Expression, purification, and crystal structure of N-terminal domains of human ubiquitin-activating enzyme (E1)Conformational transition associated with E1-E2 interaction in small ubiquitin-like modifications Role of the Zn(2+) motif of E1 in SUMO adenylation Crystal structure of a fragment of mouse ubiquitin-activating enzyme Structural and dynamic independence of isopeptide-linked RanGAP1 and SUMO-1 Pleiotropic effects of ATP.Mg2+ binding in the catalytic cycle of ubiquitin-activating enzyme Mutations in UBA3 confer resistance to the NEDD8-activating enzyme inhibitor MLN4924 in human leukemic cells Tbata modulates thymic stromal cell proliferation and thymus function Ubiquitin-binding domains Construction of a mouse Aos1-Uba2 chimeric SUMO-E1 enzyme, mAU, and its expression in baculovirus-insect cells Systematic exploration of ubiquitin sequence, E1 activation efficiency, and experimental fitness in yeast Amyloid precursor protein binding protein-1 modulates cell cycle progression in fetal neural stem cells.Isolation and sequence of an interferon-tau-inducible, pregnancy- and bovine interferon-stimulated gene product 15 (ISG15)-specific, bovine ubiquitin-activating E1-like (UBE1L) enzyme.Deciphering the ubiquitin-mediated pathway in apicomplexan parasites: a potential strategy to interfere with parasite virulence.HyperISGylation of Old World monkey ISG15 in human cells.E1 ubiquitin-activating enzyme UBA-1 plays multiple roles throughout C. elegans development.Insights into the evolution of Archaea and eukaryotic protein modifier systems revealed by the genome of a novel archaeal group.Homology Modelling of Human E1 Ubiquitin Activating Enzyme Nedd8 on cullin: building an expressway to protein destruction.Protein neddylation: beyond cullin-RING ligases.Elevated global SUMOylation in Ubc9 transgenic mice protects their brains against focal cerebral ischemic damage.

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Insights into the ubiquitin transfer cascade from the structure of the activating enzyme for NEDD8

http://www.wikidata.org/entity/Q27640736

description

2003 nî lūn-bûn

@nan

2003 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի մարտին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年論文

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2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

name

Insights into the ubiquitin tr ...... he activating enzyme for NEDD8

@ast

Insights into the ubiquitin tr ...... he activating enzyme for NEDD8

@en

Insights into the ubiquitin tr ...... he activating enzyme for NEDD8

@nl

type

label

Insights into the ubiquitin tr ...... he activating enzyme for NEDD8

@ast

Insights into the ubiquitin tr ...... he activating enzyme for NEDD8

@en

Insights into the ubiquitin tr ...... he activating enzyme for NEDD8

@nl

prefLabel

Insights into the ubiquitin tr ...... he activating enzyme for NEDD8

@ast

Insights into the ubiquitin tr ...... he activating enzyme for NEDD8

@en

Insights into the ubiquitin tr ...... he activating enzyme for NEDD8

@nl

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Insights into the ubiquitin tr ...... he activating enzyme for NEDD8

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Brenda A Schulman

http://www.w3.org/2001/XMLSchema#string

Helen Walden

http://www.w3.org/2001/XMLSchema#string

Michael S Podgorski

http://www.w3.org/2001/XMLSchema#string

P2860

Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

A new NEDD8-ligating system for cullin-4A

Improved methods for building protein models in electron density maps and the location of errors in these models

Processing of X-ray diffraction data collected in oscillation mode

Mechanism of ubiquitin activation revealed by the structure of a bacterial MoeB-MoaD complex

Crystal structure of the human ubiquitin-like protein NEDD8 and interactions with ubiquitin pathway enzymes

Mechanisms underlying ubiquitination

Automated MAD and MIR structure solution

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330-4

http://www.w3.org/2001/XMLSchema#string

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scholarly article

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2839496

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10.1038/NATURE01456

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6929

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422

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2003-03-20T00:00:00Z

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1011390168

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12646924

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P921

NEDD8 activating enzyme activity