Crystal structure of the leadzyme at 1.8 A resolution: metal ion binding and the implications for catalytic mechanism and allo site ion regulation
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Studies on Escherichia coli RNase P RNA with Zn2+ as the catalytic cofactorThe naturally trans-acting ribozyme RNase P RNA has leadzyme propertiesA comparison of vanadate to a 2'-5' linkage at the active site of a small ribozyme suggests a role for water in transition-state stabilizationA posterioridesign of crystal contacts to improve the X-ray diffraction properties of a small RNA enzymeX-ray Structures of U2 snRNA−Branchpoint Duplexes Containing Conserved Pseudouridines † ‡Water in the active site of an all-RNA hairpin ribozyme and effects of Gua8 base variants on the geometry of phosphoryl transferPrevalence of syn nucleobases in the active sites of functional RNAsMetal ion-binding properties of (N3)-deprotonated uridine, thymidine, and related pyrimidine nucleosides in aqueous solutionStructural basis for recognition of Co2+ by RNA aptamers.Exploring ribozyme conformational changes with X-ray crystallography.NMR and XAS reveal an inner-sphere metal binding site in the P4 helix of the metallo-ribozyme ribonuclease P.Computational identification of RNA functional determinants by three-dimensional quantitative structure-activity relationships.Structure, dynamics, and mechanism of the lead-dependent ribozyme.Searching for a DNAzyme Version of the Leadzyme.Non-nearest-neighbor dependence of the stability for RNA bulge loops based on the complete set of group I single-nucleotide bulge loops.Cation-specific structural accommodation within a catalytic RNA.Raman crystallography of RNA.Strategies for Characterization of Enzymatic Nucleic Acids.Crystallographic analysis of small ribozymes and riboswitches.Conformationally restricted nucleotides as a probe of structure-function relationships in RNA.A CA(+) pair adjacent to a sheared GA or AA pair stabilizes size-symmetric RNA internal loops.Multiple functions for the invariant AGC triad of U6 snRNA.A catalytic metal ion interacts with the cleavage Site G.U wobble in the HDV ribozyme.Automated identification of RNA 3D modules with discriminative power in RNA structural alignments.Crystallization and X-ray diffraction analysis of the Trp/amber editing site of hepatitis delta virus (+)RNA: a case of rational design.Hydrostatic and osmotic pressure study of the RNA hydration.Solution probing of metal ion binding by helix 27 from Escherichia coli 16S rRNA.Two interacting proteins are necessary for the editing of the NdhD-1 site in Arabidopsis plastids.Leadzyme formed in vivo interferes with tobacco mosaic virus infection in Nicotiana tabacum.Modulation of Ribozyme and Deoxyribozyme Activities Using Tetraalkylammonium Ions.Blind prediction of noncanonical RNA structure at atomic accuracy.
P2860
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P2860
Crystal structure of the leadzyme at 1.8 A resolution: metal ion binding and the implications for catalytic mechanism and allo site ion regulation
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Crystal structure of the leadz ...... m and allo site ion regulation
@ast
Crystal structure of the leadz ...... m and allo site ion regulation
@en
Crystal structure of the leadz ...... m and allo site ion regulation
@nl
type
label
Crystal structure of the leadz ...... m and allo site ion regulation
@ast
Crystal structure of the leadz ...... m and allo site ion regulation
@en
Crystal structure of the leadz ...... m and allo site ion regulation
@nl
prefLabel
Crystal structure of the leadz ...... m and allo site ion regulation
@ast
Crystal structure of the leadz ...... m and allo site ion regulation
@en
Crystal structure of the leadz ...... m and allo site ion regulation
@nl
P356
P1433
P1476
Crystal structure of the leadz ...... m and allo site ion regulation
@en
P2093
David B McKay
Joseph E Wedekind
P304
P356
10.1021/BI0300783
P407
P577
2003-08-19T00:00:00Z