Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain
about
Structural basis for extracellular interactions between calcitonin receptor-like receptor and receptor activity-modifying protein 2 for adrenomedullin-specific bindingStructure of class B GPCR corticotropin-releasing factor receptor 1Molecular recognition of corticotropin-releasing factor by its G-protein-coupled receptor CRFR1Lacritin and other new proteins of the lacrimal functional unitStructural basis for parathyroid hormone-related protein binding to the parathyroid hormone receptor and design of conformation-selective peptidesMolecular basis for negative regulation of the glucagon receptorLacritin rescues stressed epithelia via rapid forkhead box O3 (FOXO3)-associated autophagy that restores metabolismTargeting of heparanase-modified syndecan-1 by prosecretory mitogen lacritin requires conserved core GAGAL plus heparan and chondroitin sulfate as a novel hybrid binding site that enhances selectivityHomozygous P86S mutation of the human glucagon receptor is associated with hyperglucagonemia, alpha cell hyperplasia, and islet cell tumorLandmark studies on the glucagon subfamily of GPCRs: from small molecule modulators to a crystal structureStructure and mechanism for recognition of peptide hormones by Class B G-protein-coupled receptorsCrystal Structure of Glucagon-like Peptide-1 in Complex with the Extracellular Domain of the Glucagon-like Peptide-1 ReceptorDimeric Arrangement of the Parathyroid Hormone Receptor and a Structural Mechanism for Ligand-induced DissociationNMR Structure of the First Extracellular Domain of Corticotropin-releasing Factor Receptor 1 (ECD1-CRF-R1) Complexed with a High Affinity AgonistConformational and molecular interaction studies of glucagon-like peptide-2 with its N-terminal extracellular receptor domainCrystal Structure of the PAC1R Extracellular Domain Unifies a Consensus Fold for Hormone Recognition by Class B G-Protein Coupled ReceptorsGlucagon-Like Peptide-1 and Its Class B G Protein-Coupled Receptors: A Long March to Therapeutic SuccessesTransmembrane signal transduction by peptide hormones via family B G protein-coupled receptorsStructural insights into ligand recognition and selectivity for classes A, B, and C GPCRsConformational states of the full-length glucagon receptorStructural Determinants of Binding the Seven-transmembrane Domain of the Glucagon-like Peptide-1 Receptor (GLP-1R)Structural basis for hormone recognition by the Human CRFR2{alpha} G protein-coupled receptorA novel glucagon-related peptide (GCRP) and its receptor GCRPR account for coevolution of their family members in vertebratesGlucagon-like peptide-1 receptor ligand interactions: structural cross talk between ligands and the extracellular domainQuantitative Impact of Plasma Clearance and Down-regulation on GLP-1 Receptor Molecular Imaging.Dual-purpose linker for alpha helix stabilization and imaging agent conjugation to glucagon-like peptide-1 receptor ligands.Model of the complex of Parathyroid hormone-2 receptor and Tuberoinfundibular peptide of 39 residuesMolecular basis of glucagon-like peptide 1 docking to its intact receptor studied with carboxyl-terminal photolabile probesA β-peptide agonist of the GLP-1 receptor, a class B GPCR.Pharmacological characterization of human incretin receptor missense variantsGenetically encoded photocross-linkers determine the biological binding site of exendin-4 peptide in the N-terminal domain of the intact human glucagon-like peptide-1 receptor (GLP-1R)Non-peptidic glucose-like peptide-1 receptor agonists: aftermath of a serendipitous discovery.Secretin occupies a single protomer of the homodimeric secretin receptor complex: insights from photoaffinity labeling studies using dual sites of covalent attachment.Structural study of an active analog of EX-4 in solution and micelle associated states.Purification of family B G protein-coupled receptors using nanodiscs: Application to human glucagon-like peptide-1 receptorSeven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery.Role of N-linked glycosylation in biosynthesis, trafficking, and function of the human glucagon-like peptide 1 receptorSpatial approximations between residues 6 and 12 in the amino-terminal region of glucagon-like peptide 1 and its receptor: a region critical for biological activity.Elucidation of the active conformation of the amino terminus of receptor-bound secretin using intramolecular disulfide bond constraints.Mutational and cysteine scanning analysis of the glucagon receptor N-terminal domain.
P2860
Q24298039-F9055E4F-9828-47A8-BC6E-7112FF78638CQ24309523-6BE626AF-BA98-4508-8C98-A802BDC070B1Q24314090-8433885A-26EB-4D36-89A4-108972D20C40Q24320688-86940EDB-9FAD-4FED-A610-564C58238F55Q24324153-B57DA115-78DB-4B14-A5E7-B7A47208F245Q24604062-B4F8154F-3476-4E91-A1C4-1D4D80476B23Q24609781-BEB0D116-A235-4156-AA90-B63DC623FC1BQ24631177-D59DD65C-7990-4319-A65F-DBF08F8A9634Q24648531-5B9363F2-3A5A-41A6-A701-CCBE48AA2814Q26798049-007BDACE-263D-4E14-AA47-61681FDB52F6Q26851381-32E5D5B3-82A9-4243-8EFC-54E97277364CQ27657999-BFB0CE42-EA13-42BC-88F6-715B435E5C71Q27659967-99D37CF3-DA2C-45EA-8355-FD34B31F1DC3Q27664491-81D589FA-70EE-4216-BAAE-8F2A5CC1FB44Q27666380-EFDFED20-A0D5-4396-86E1-D7111D576567Q27668088-36AFADFF-7B33-47AD-9A76-FB5C457427DBQ28067465-B76D5599-A843-4ADD-BB0B-702C4BD9FD0AQ28082755-0C9E8AB6-B4E8-489A-891C-EE943E55707DQ28088311-1823A208-CA04-479F-A99F-531C8CF8D25CQ28265667-1BEFAFCB-0DAF-4EC4-B2B8-58920131489EQ28274664-1C2842ED-BD15-466D-9BC5-C8EF38E3ADC2Q28296331-00044C13-5030-49B8-8CB5-F1D1021AA3A0Q28533808-5373F174-E161-483A-A164-3A3D45B932E3Q28542687-0AB46AB7-A76A-4074-8383-7E519606EE3EQ30364628-61272457-CA6E-40B2-A67A-4247B6B0587AQ30379845-97F55419-271A-4E07-BB96-EB6A69CE1E30Q30478575-2DD27110-EEC4-4A16-9941-CDE7499D6475Q33553466-C0A41850-90EE-472F-AC84-16002561FA00Q33553641-E84A9CC3-ABC7-43D0-9758-0D727EBE9A6AQ33574960-54072973-3930-4DB5-9C3A-9A43AE4676B7Q33615669-F5C96783-826B-4CE7-8823-60C1B4A25BA7Q33646569-372FA600-31AE-48A5-8384-024F5F7F90B9Q33744723-68207F05-B6E1-4F83-8469-9F7367788504Q33745444-30BB1234-B54C-493A-9EB8-A6EEFE4634F0Q33793135-1744190B-43AA-47C7-B211-F678718BE77DQ33890786-AD757D23-C28D-476A-AEDE-583912D89ACCQ33994409-5E0F8F96-D9ED-4D4A-B81F-6ECE6B5398C7Q34042564-B586C15C-57E4-46D7-AE05-07E425A94E87Q34143310-70238F9E-018B-4793-A4A4-D0833C509402Q34155428-9DC69184-D0C7-415C-8055-C83F6881C10B
P2860
Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain
description
2008 nî lūn-bûn
@nan
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Crystal structure of the ligan ...... receptor extracellular domain
@ast
Crystal structure of the ligan ...... receptor extracellular domain
@en
Crystal structure of the ligan ...... receptor extracellular domain
@nl
type
label
Crystal structure of the ligan ...... receptor extracellular domain
@ast
Crystal structure of the ligan ...... receptor extracellular domain
@en
Crystal structure of the ligan ...... receptor extracellular domain
@nl
prefLabel
Crystal structure of the ligan ...... receptor extracellular domain
@ast
Crystal structure of the ligan ...... receptor extracellular domain
@en
Crystal structure of the ligan ...... receptor extracellular domain
@nl
P2093
P2860
P3181
P356
P1476
Crystal structure of the ligan ...... receptor extracellular domain.
@en
P2093
Henning Thøgersen
Jesper Lau
Kjeld Madsen
Rainer Rudolph
Steffen Runge
P2860
P304
P3181
P356
10.1074/JBC.M708740200
P407
P577
2008-04-25T00:00:00Z