Structure of the Hsp110:Hsc70 nucleotide exchange machine.
about
Identification of a potential tumor differentiation factor receptor candidate in prostate cancer cellsMolecular chaperones: guardians of the proteome in normal and disease statesThe nucleotide exchange factors of Hsp70 molecular chaperonesMetazoan Hsp70-based protein disaggregases: emergence and mechanismsInsights into the molecular mechanism of allostery in Hsp70s.Fine-tuning multiprotein complexes using small moleculesBiP and its nucleotide exchange factors Grp170 and Sil1: mechanisms of action and biological functionsChaperone machines for protein folding, unfolding and disaggregationExtrapolation of Inter Domain Communications and Substrate Binding Cavity of Camel HSP70 1A: A Molecular Modeling and Dynamics Simulation StudyMolecular mechanism of allosteric communication in Hsp70 revealed by molecular dynamics simulationsStructural basis of nucleotide exchange and client binding by the Hsp70 cochaperone Bag2Crystal Structures of the ATPase Domains of Four Human Hsp70 Isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78Biochemical and structural studies on the high affinity of Hsp70 for ADPStructural analysis of the Sil1-Bip complex reveals the mechanism for Sil1 to function as a nucleotide-exchange factorStructure and function of Hip, an attenuator of the Hsp70 chaperone cycleStructural and functional analysis of Hikeshi, a new nuclear transport receptor of Hsp70sClathrin coat disassembly by the yeast Hsc70/Ssa1p and auxilin/Swa2p proteins observed by single-particle burst analysis spectroscopy.Nucleotide binding by Lhs1p is essential for its nucleotide exchange activity and for function in vivo.Plasmodium falciparum Hsp70-z, an Hsp110 homologue, exhibits independent chaperone activity and interacts with Hsp70-1 in a nucleotide-dependent fashionThe human HSP70 family of chaperones: where do we stand?Allostery in the Hsp70 chaperone proteinsProteomic data from human cell cultures refine mechanisms of chaperone-mediated protein homeostasisA Non-enveloped Virus Hijacks Host Disaggregation Machinery to Translocate across the Endoplasmic Reticulum MembraneLarge-Scale Conformational Transitions and Dimerization Are Encoded in the Amino-Acid Sequences of Hsp70 ChaperonesAllostery in Hsp70 chaperones is transduced by subdomain rotationsBinding of human nucleotide exchange factors to heat shock protein 70 (Hsp70) generates functionally distinct complexes in vitroThe HSP70 chaperone machinery: J proteins as drivers of functional specificityPlasmodium falciparum heat shock protein 110 stabilizes the asparagine repeat-rich parasite proteome during malarial feversHSPA8/HSC70 chaperone protein: structure, function, and chemical targeting.ATP-induced conformational changes in Hsp70: molecular dynamics and experimental validation of an in silico predicted conformation.Hsp110 is required for spindle length control.Progressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALS.Hierarchical functional specificity of cytosolic heat shock protein 70 (Hsp70) nucleotide exchange factors in yeast.Structure of clathrin coat with bound Hsc70 and auxilin: mechanism of Hsc70-facilitated disassembly.Role of Hsp70 ATPase domain intrinsic dynamics and sequence evolution in enabling its functional interactions with NEFs.Key interactions for clathrin coat stability.Hsp110 chaperones control client fate determination in the hsp70-Hsp90 chaperone systemMutagenesis reveals the complex relationships between ATPase rate and the chaperone activities of Escherichia coli heat shock protein 70 (Hsp70/DnaK)Molecular chaperones are nanomachines that catalytically unfold misfolded and alternatively folded proteins.Loss of Hsp110 leads to age-dependent tau hyperphosphorylation and early accumulation of insoluble amyloid beta.
P2860
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P2860
Structure of the Hsp110:Hsc70 nucleotide exchange machine.
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structure of the Hsp110:Hsc70 Nucleotide Exchange Machine
@nl
Structure of the Hsp110:Hsc70 nucleotide exchange machine.
@ast
Structure of the Hsp110:Hsc70 nucleotide exchange machine.
@en
type
label
Structure of the Hsp110:Hsc70 Nucleotide Exchange Machine
@nl
Structure of the Hsp110:Hsc70 nucleotide exchange machine.
@ast
Structure of the Hsp110:Hsc70 nucleotide exchange machine.
@en
prefLabel
Structure of the Hsp110:Hsc70 Nucleotide Exchange Machine
@nl
Structure of the Hsp110:Hsc70 nucleotide exchange machine.
@ast
Structure of the Hsp110:Hsc70 nucleotide exchange machine.
@en
P2093
P2860
P50
P3181
P1433
P1476
Structure of the Hsp110:Hsc70 nucleotide exchange machine.
@en
P2093
Alexander B Taylor
Borries Demeler
Jianwen Jiang
Jonathan P Schuermann
Jorge Cuellar
Liping Wang
Luis E Gimenez
P John Hart
Suping Jin
P2860
P304
P3181
P356
10.1016/J.MOLCEL.2008.05.006
P577
2008-06-12T00:00:00Z