Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure
about
Rho-kinase/ROCK: A key regulator of the cytoskeleton and cell polarityRho-associated kinases in tumorigenesis: re-considering ROCK inhibition for cancer therapyNovel Insights into the Roles of Rho Kinase in CancerGenetic deletion of Rnd3/RhoE results in mouse heart calcium leakage through upregulation of protein kinase A signaling.Structure of dystrophia myotonica protein kinaseCrystal structure of the catalytic domain of Haspin, an atypical kinase implicated in chromatin organizationStructural Basis of the Substrate Specificity of Bifunctional Isocitrate Dehydrogenase Kinase/PhosphataseStructure of Shroom domain 2 reveals a three-segmented coiled-coil required for dimerization, Rock binding, and apical constrictionPathophysiological Functions of Rnd3/RhoEA molecular ruler regulates cytoskeletal remodelling by the Rho kinasesRnd3 regulation of the actin cytoskeleton promotes melanoma migration and invasive outgrowth in three dimensionsROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherensThe RhoA GEF Syx is a target of Rnd3 and regulated via a Raf1-like ubiquitin-related domain.Regulation of Rnd3 localization and function by protein kinase C alpha-mediated phosphorylation.ROCK is involved in vasculogenic mimicry formation in hepatocellular carcinoma cell lineRhoA/Rho-kinase and vascular diseases: what is the link?Regulation of the postsynaptic cytoskeleton: roles in development, plasticity, and disorders.Function and regulation of Rnd proteins in cortical projection neuron migrationProneural transcription factors regulate different steps of cortical neuron migration through Rnd-mediated inhibition of RhoA signalingThe GTPase-deficient Rnd proteins are stabilized by their effectors.Discovery of Novel ROCK1 Inhibitors via Integrated Virtual Screening Strategy and Bioassays.Rnd3 induces stress fibres in endothelial cells through RhoBSubstrate recognition of PLCγ1 via a specific docking surface on Itk.Rho kinases in cardiovascular physiology and pathophysiology: the effect of fasudil.Comparative transcriptomics reveals RhoE as a novel regulator of actin dynamics in bone-resorbing osteoclasts.Pseudokinases-remnants of evolution or key allosteric regulators?Rho-kinase: important new therapeutic target in cardiovascular diseases.Made to measure - keeping Rho kinase at a distance.RhoE is required for contact inhibition and negatively regulates tumor initiation and progression.Rnd3-induced cell rounding requires interaction with Plexin-B2.Thermodynamic characterization of two homologous protein complexes: associations of the semaphorin receptor plexin-B1 RhoGTPase binding domain with Rnd1 and active Rac1.Structural Basis for Auto-Inhibition of the NDR1 Kinase Domain by an Atypically Long Activation Segment
P2860
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P2860
Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure
@ast
Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure
@en
Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure
@nl
type
label
Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure
@ast
Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure
@en
Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure
@nl
prefLabel
Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure
@ast
Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure
@en
Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure
@en
P2093
David Barford
Paul T C Wan
P2860
P304
P3181
P356
10.1038/EMBOJ.2008.226
P407
P577
2008-12-03T00:00:00Z