The Fatty Acid Biosynthesis Enzyme FabI Plays a Key Role in the Development of Liver-Stage Malarial Parasites - Wikidata - thesis-toulmin - TriplyDB

The Fatty Acid Biosynthesis Enzyme FabI Plays a Key Role in the Development of Liver-Stage Malarial Parasites

The Fatty Acid Biosynthesis Enzyme FabI Plays a Key Role in the Development of Liver-Stage Malarial Parasites

http://www.wikidata.org/entity/Q27653089

about

enoyl-acyl carrier reductase enoyl-acyl carrier reductase, putative

P1343

What do human parasites do with a chloroplast anyway?That Was Then But This Is Now: Malaria Research in the Time of an Eradication Agenda Bromopyrrole alkaloids as lead compounds against protozoan parasites The evolution, metabolism and functions of the apicoplast Global phenotypic screening for antimalarials The metabolic roles of the endosymbiotic organelles of Toxoplasma and Plasmodium spp Using genetic methods to define the targets of compounds with antimalarial activity Lipoic acid metabolism of Plasmodium--a suitable drug target Chemical rescue of malaria parasites lacking an apicoplast defines organelle function in blood-stage Plasmodium falciparum Plasmodium falciparumacyl carrier protein crystal structures in disulfide-linked and reduced states and their prevalence during blood stage growth The benzimidazole based drugs show good activity against T. gondii but poor activity against its proposed enoyl reductase enzyme target A systematic screen to discover and analyze apicoplast proteins identifies a conserved and essential protein import factor Deconvoluting heme biosynthesis to target blood-stage malaria parasites Type II fatty acid biosynthesis is essential for Plasmodium falciparum sporozoite development in the midgut of Anopheles mosquitoes Enzymes involved in plastid-targeted phosphatidic acid synthesis are essential for Plasmodium yoelii liver-stage development Characterization of two putative protein translocation components in the apicoplast of Plasmodium falciparum Characterization of the Plasmodium falciparum and P. berghei glycerol 3-phosphate acyltransferase involved in FASII fatty acid utilization in the malaria parasite apicoplast The suf iron-sulfur cluster synthesis pathway is required for apicoplast maintenance in malaria parasites The Halogen Bond Stage-Specific Changes in Plasmodium Metabolism Required for Differentiation and Adaptation to Different Host and Vector Environments Transcriptional analysis of the pre-erythrocytic stages of the rodent malaria parasite, Plasmodium yoelii Identification and characterization of a liver stage-specific promoter region of the malaria parasite Plasmodium Oleic acid biosynthesis in Plasmodium falciparum: characterization of the stearoyl-CoA desaturase and investigation as a potential therapeutic target Branched tricarboxylic acid metabolism in Plasmodium falciparum A chemical rescue screen identifies a Plasmodium falciparum apicoplast inhibitor targeting MEP isoprenoid precursor biosynthesis Inactivation of a Plasmodium apicoplast protein attenuates formation of liver merozoites A Novel and Conserved Plasmodium Sporozoite Membrane Protein SPELD is Required for Maturation of Exo-erythrocytic Forms Discovery of compounds blocking the proliferation of Toxoplasma gondii and Plasmodium falciparum in a chemical space based on piperidinyl-benzimidazolone analogs.The Alveolate Perkinsus marinus: biological insights from EST gene discovery.Role of Plasmodium berghei cGMP-dependent protein kinase in late liver stage development Eating at the table of another: metabolomics of host-parasite interactions.Malaria parasite development in the mosquito and infection of the mammalian host.Engineering of Genetically Arrested Parasites (GAPs) For a Precision Malaria Vaccine A novel genetic technique in Plasmodium berghei allows liver stage analysis of genes required for mosquito stage development and demonstrates that de novo heme synthesis is essential for liver stage development in the malaria parasite An update on the rapid advances in malaria parasite cell biology.Lipoic acid metabolism in microbial pathogens.Targeting the Lipid Metabolic Pathways for the Treatment of Malaria.Recent insights into fatty acid acquisition and metabolism in malarial parasites.Reconstruction and flux-balance analysis of the Plasmodium falciparum metabolic network.2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage Plasmodium infections.

P2860

0413e03575a68786c6e02b43cc3f37f7424ca2ea 5479b3326db1878d56d90e81a8e1e3eaa456c4fb 82b5a346f352dc654d2ec5df374d295ee9f4a364 938c9222fc78f631bf682169b15f30a6eba1f62f c1e9f202e8450fbab0c6c8ffe62411f17e8b79f9 ebf8cf1657440d5c86f0c859a25fdce0d61b781c

P248

Q59918907-0C98E9F5-49A7-4047-A019-17BB0DDEFB8F Q59991348-C53149CF-F3E0-4051-920D-ABC77A6C13AF

P1343

Q21145764-3F853806-CC82-4BAA-B414-2DB28EE87EDC Q22061808-27929B20-7149-4FC6-AF69-EC6DC976BE5F Q24632744-0A2B629A-2E9C-48A4-B670-0634760C1CFE Q24652914-A9B54A72-0F8E-4B12-9890-0FD616C370FE Q26824875-59F75D92-AF6B-46B3-A1E4-DA40747BE8EF Q26862413-7ED36039-FD27-4FB8-A1FF-2AAE414375F0 Q27014788-5BF1A961-1DCB-402E-AC9A-FCE81A792AD6 Q27026939-58309955-08D8-4920-BDC4-81A01CD7DA6D Q27321104-9D8F50C0-1796-42FA-908D-72B32656C7A5 Q27657492-8A1BE7E3-8915-4580-BD24-4F5F57400F4A Q27681222-134C05F8-EC7D-4FAA-8BBC-2E9A5D6F1917 Q27972570-82A88463-9FC2-4CAE-8F47-71FE537552A8 Q27973107-7D43C0AC-F04C-4DA8-B901-1D60569F6A98 Q27973456-E59541B0-0875-4F12-8B61-560AB186230E Q27973703-09C6900D-E8C9-4F68-9163-FDF3DDB54A4A Q27973975-3C2A8CB2-14D1-4AA0-A0C3-6951C4D240E0 Q27974045-A78065D1-AE62-43D7-9ADF-81101CB492CB Q27974759-D972328F-419C-4C56-AD61-249339B9B8CA Q28077775-0A70ECD9-EFAD-4235-B152-EBB239563B37 Q28468534-4F9AB720-5CB3-4E04-94BC-72F6E8F0B2F8 Q28473729-7A01E05D-4559-4494-A7D9-AEB797D175AD Q28475936-4F52BA3D-054E-41DF-9DBD-62DA0D2D138F Q28476054-855B23E8-7767-4322-9B2D-8855FA471AD7 Q30041050-BB1D856A-3125-4065-B9BA-D3C804C04737 Q30043334-54154A52-8493-4B13-8239-AF5D2657DCD2 Q30043892-1DFEA07A-6C36-47E6-875D-72D1B6980394 Q30044206-2A21F537-2F67-47C4-AB75-BFFCE813C33D Q30576511-9EB61FCA-F570-46B2-9F37-8A3DD7E49F84 Q33550603-6634C0B8-6B43-4540-8957-1E6C6EFD624A Q33661363-7DEC530E-11F4-48EB-98C3-8C36350173F0 Q33671828-5DA387BE-5633-4E67-BAFB-E4F83CAF90FC Q33738231-4D59149C-2DB2-4EAD-99B7-3851AE35F0A6 Q33744460-5655757B-C2B5-4822-A068-2FBE20F2694C Q33803291-4C03355F-31C4-4D17-8D36-B72613417F87 Q33905946-50CE4EFB-5698-4FE3-B0E4-D6B451438070 Q33909117-6D21CBA8-25B5-437F-903A-44003EAC3A06 Q33915847-0326D6BE-E384-449D-A489-07A787B40B9F Q34167505-E5F663D4-1FBF-484A-A65B-0AFF93794137 Q34240829-F9AC8433-00E5-468B-AE16-F176BA763840 Q34312282-99A8BC23-494A-46FD-96F2-BC7DEEC46C4D

P2860

The Fatty Acid Biosynthesis Enzyme FabI Plays a Key Role in the Development of Liver-Stage Malarial Parasites

http://www.wikidata.org/entity/Q27653089

description

2008 nî lūn-bûn

@nan

2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

The Fatty Acid Biosynthesis En ...... Liver-Stage Malarial Parasites

@ast

The Fatty Acid Biosynthesis En ...... Liver-Stage Malarial Parasites

@en

The Fatty Acid Biosynthesis En ...... Liver-Stage Malarial Parasites

@nl

type

label

The Fatty Acid Biosynthesis En ...... Liver-Stage Malarial Parasites

@ast

The Fatty Acid Biosynthesis En ...... Liver-Stage Malarial Parasites

@en

The Fatty Acid Biosynthesis En ...... Liver-Stage Malarial Parasites

@nl

prefLabel

The Fatty Acid Biosynthesis En ...... Liver-Stage Malarial Parasites

@ast

The Fatty Acid Biosynthesis En ...... Liver-Stage Malarial Parasites

@en

The Fatty Acid Biosynthesis En ...... Liver-Stage Malarial Parasites

@nl

P1433

Q27653089-5A31BCD3-5648-486C-9295-E5D81410D84C

P1476

Q27653089-2CAB49A8-9682-4282-87D1-D8B66C9C36B3

P2093

Q27653089-07C9CE50-6117-4884-AF5F-F2B6C172BB70

Q27653089-108A128B-B3FA-4195-9A47-52AE8C4EF2F8

Q27653089-27C310E2-D086-469C-87D7-F1042A7B3239

Q27653089-332B5F16-5864-4C5A-BC18-1B8347FAFCC8

Q27653089-3C4AF61E-EE80-4DBA-969C-4CE65297011A

Q27653089-41E955F7-4E8D-41AA-BEE2-9B93A0707502

Q27653089-55556474-1310-4021-989C-16D5E9317B11

Q27653089-573C4785-C368-4934-819E-F959C8B39111

Q27653089-5BBFDFCD-2666-40F5-B211-3750A6361FB7

Q27653089-5C849D88-235C-41BD-867D-AD7B6A5C1E40

P2860

Q27653089-09742972-96B9-4FFD-97DB-2E554B53033C

Q27653089-0A1C34CB-B24D-4573-AE39-B28DEED44990

Q27653089-0B1D17FC-016F-4573-B009-26A0C403AAE3

Q27653089-0CF4821E-C431-47EF-9EF3-65D7402D7408

Q27653089-0ECF5030-1AB4-4048-B7CA-8D21DD641DF6

Q27653089-1AA5896F-3D80-4916-88E6-7E042FCF7C4A

Q27653089-30A553F3-034E-4137-84ED-C582DF3CEEA3

Q27653089-3127BD8B-ECFF-4E64-A4FB-D5252EE75524

Q27653089-410B5BF9-3A1D-4B91-9A64-70BF8BFF759C

Q27653089-43AF037B-3B63-4A69-90AB-5D15E4717D7E

P304

Q27653089-C9D3B769-6D48-4268-81B5-5AF95CBBD789

P31

Q27653089-A2168171-4D3E-48F0-9077-8E0BA3DD574E

P3181

Q27653089-CB204C49-6E9A-4119-AC64-5F60E919D172

P356

Q27653089-2714A866-6F08-411D-B3E2-497F713D4641

P433

Q27653089-3519158F-483E-47FE-8247-E5FB92C21E0F

P478

Q27653089-051307A3-AA1E-4964-974B-4A5DAA59E232

P50

Q27653089-020B0C19-E8F8-41DF-A4E8-DDC13E9E6579

Q27653089-075EBD48-FFA9-425B-A497-E98E59BCC430

Q27653089-2E1A25D2-DEF3-4061-8648-20F9A2FC87A1

Q27653089-54732555-5A9B-461F-A82C-9F12053BEB1C

Q27653089-63F52C20-8831-4AEA-8E1A-DBEC26602D2C

Q27653089-81F456A6-3575-4CED-B056-25B0F9DB2DBF

Q27653089-F4BD487A-AB4C-46E1-9CC8-E93AB084512B

P577

Q27653089-77A433C9-A4B3-4B71-A294-3B3E3C7D15EF

P5875

Q27653089-69756473-BF17-4977-B780-2F3852BF8974

P698

Q27653089-B08D3B83-7A5A-4385-9E14-74D60178D293

P921

Q27653089-11E5F30F-F4B0-4A09-9BAD-0D7E77DC8344

Q27653089-321784BA-8C15-4EA4-B0AE-A3FA30A12475

Q27653089-3DA50DEE-1DA7-4D5B-A731-62CCAD17C832

Q27653089-3FFDF045-2F68-49C1-9137-43085C449F5E

Q27653089-4E2773F2-7D2A-4920-A1C3-5D274D5A84F3

Q27653089-5ACC7380-E235-43E2-82FC-DB7E774F2FDA

Q27653089-5E237A1F-7623-4FCE-9B8B-04EC88C1A48B

Q27653089-7578D4C0-518D-4BED-8DE2-FF6B70107603

Q27653089-7A59AFCF-9254-4CAA-97B1-0BD12F89784F

Q27653089-8C7335D6-3326-4E2F-88F0-D54CD2CCDAB0

P932

Q27653089-B2760928-6DB4-495C-8320-05D9C48839C0

P3181

P356

J.CHOM.2008.11.001

P1433

Cell Host & Microbe

P1476

The fatty acid biosynthesis en ...... liver-stage malarial parasites

@en

P2093

Alida Coppi

http://www.w3.org/2001/XMLSchema#string

Amar Bir Singh Sidhu

http://www.w3.org/2001/XMLSchema#string

Arba Ager

http://www.w3.org/2001/XMLSchema#string

Brie Falkard

http://www.w3.org/2001/XMLSchema#string

Catherine Vilcheze

http://www.w3.org/2001/XMLSchema#string

Celeste D Li

http://www.w3.org/2001/XMLSchema#string

David P Jacobus

http://www.w3.org/2001/XMLSchema#string

Guy Schiehser

http://www.w3.org/2001/XMLSchema#string

James C Sacchettini

http://www.w3.org/2001/XMLSchema#string

Jennifer H-C Tsai

http://www.w3.org/2001/XMLSchema#string

P2860

Efficient site-specific integration in Plasmodium falciparum chromosomes mediated by mycobacteriophage Bxb1 integrase

Malaria: progress, perils, and prospects for eradication

Structural elucidation of the specificity of the antibacterial agent triclosan for malarial enoyl acyl carrier protein reductase

X-ray structural analysis of Plasmodium falciparum enoyl acyl carrier protein reductase as a pathway toward the optimization of triclosan antimalarial efficacy

Identification and stoichiometry of glycosylphosphatidylinositol-anchored membrane proteins of the human malaria parasite Plasmodium falciparum

A sporozoite asparagine-rich protein controls initiation of Plasmodium liver stage development

Vibrio cholerae FabV defines a new class of enoyl-acyl carrier protein reductase

Duplication, gene conversion, and genetic diversity in the species-specific acyl-CoA synthetase gene family of Plasmodium falciparum

Triclosan offers protection against blood stages of malaria by inhibiting enoyl-ACP reductase of Plasmodium falciparum

Tropical infectious diseases: metabolic maps and functions of the Plasmodium falciparum apicoplast

P304

567-578

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

447044

http://www.w3.org/2001/XMLSchema#string

P356

10.1016/J.CHOM.2008.11.001

http://www.w3.org/2001/XMLSchema#string

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

4

http://www.w3.org/2001/XMLSchema#string

P50

David A. Fidock

Volker Heussler

Brendan J Kelly

P577

2008-12-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

23639649

http://www.w3.org/2001/XMLSchema#string

P698

19064257

http://www.w3.org/2001/XMLSchema#string

P921

enoyl-acyl carrier reductase

enoyl-acyl carrier reductase, putative

enoyl-acyl carrier reductase, putative

enoyl-acyl carrier reductase, putative

enoyl-acyl carrier reductase

enoyl-acyl carrier reductase, putative

enoyl-acyl carrier reductase, putative

enoyl-acyl carrier reductase, putative

enoyl-acyl carrier reductase, putative

P932

2646117

http://www.w3.org/2001/XMLSchema#string