Crystal structure of the OXA-48 beta-lactamase reveals mechanistic diversity among class D carbapenemases
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"Stormy waters ahead": global emergence of carbapenemasesCarbapenems: past, present, and futureCharacterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from IndiaLaboratory Detection and Clinical Implication of Oxacillinase-48 like Carbapenemase: The Hidden ThreatCrystal Structure of OXA-58 with the Substrate-Binding Cleft in a Closed State: Insights into the Mobility and Stability of the OXA-58 StructureCrystal Structure of the Narrow-Spectrum OXA-46 Class D -Lactamase: Relationship between Active-Site Lysine Carbamylation and Inhibition by PolycarboxylatesDesign, Synthesis, and Crystal Structures of 6-Alkylidene-2′-Substituted Penicillanic Acid Sulfones as Potent Inhibitors of Acinetobacter baumannii OXA-24 CarbapenemaseThree factors that modulate the activity of class D β-lactamases and interfere with the post-translational carboxylation of Lys70Structures of the Class D Carbapenemase OXA-24 from Acinetobacter baumannii in Complex with DoripenemLysine N -Decarboxylation Switch and Activation of the -Lactam Sensor Domain of BlaR1 Protein of Methicillin-resistant Staphylococcus aureusEvolution to carbapenem-hydrolyzing activity in noncarbapenemase class D -lactamase OXA-10 by rational protein designStructures of the Class D Carbapenemases OXA-23 and OXA-146: Mechanistic Basis of Activity against Carbapenems, Extended-Spectrum Cephalosporins, and AztreonamStructural Basis for Carbapenemase Activity of the OXA-23 β-Lactamase from Acinetobacter baumanniiStructural Origins of Oxacillinase Specificity in Class D -LactamasesCrystal Structure of Carbapenemase OXA-58 from Acinetobacter baumanniiStructural Basis for Different Substrate Profiles of Two Closely Related Class D β-Lactamases and Their Inhibition by HalogensRemoval of the Side Chain at the Active-Site Serine by a Glycine Substitution Increases the Stability of a Wide Range of Serine β-Lactamases by Relieving Steric StrainThe structure of a doripenem-bound OXA-51 class D β-lactamase variant with enhanced carbapenemase activityStructural basis for carbapenem-hydrolyzing mechanisms of carbapenemases conferring antibiotic resistanceClass D β-lactamases: a reappraisal after five decadesPenicillin sulfone inhibitors of class D beta-lactamasesIn vitro activity of ceftazidime+NXL104 against Pseudomonas aeruginosa and other non-fermenters.A fluorescent carbapenem for structure function studies of penicillin-binding proteins, β-lactamases, and β-lactam sensors.Detection of OXA-48-type carbapenemase-producing Enterobacteriaceae in diagnostic laboratories can be enhanced by addition of bicarbonates to cultivation media or reaction buffers.Genetic and biochemical characterization of OXA-405, an OXA-48-type extended-spectrum β-lactamase without significant carbapenemase activity.Structural basis of activity against aztreonam and extended spectrum cephalosporins for two carbapenem-hydrolyzing class D β-lactamases from Acinetobacter baumannii.Structural Basis for Enhancement of Carbapenemase Activity in the OXA-51 Family of Class D β-Lactamases.Structure-based approach for identification of novel phenylboronic acids as serine-β-lactamase inhibitors.Carbapenemases in Klebsiella pneumoniae and other Enterobacteriaceae: an evolving crisis of global dimensionsClass D β-lactamases do exist in Gram-positive bacteria.Treatment options for infections caused by carbapenem-resistant Enterobacteriaceae: can we apply "precision medicine" to antimicrobial chemotherapy?Prevalence and Molecular Characteristics of Carbapenemase-Producing Enterobacteriaceae From Five Hospitals in Korea.Clinical Variants of the Native Class D β-Lactamase of Acinetobacter baumannii Pose an Emerging Threat through Increased Hydrolytic Activity against CarbapenemsKinetic characterization of GES-22 β-lactamase harboring the M169L clinical mutation.Efficacy of humanized carbapenem and ceftazidime regimens against Enterobacteriaceae producing OXA-48 carbapenemase in a murine infection model.A high-throughput, restriction-free cloning and screening strategy based on ccdB-gene replacement.OXA-48-like carbapenemases: the phantom menace.Bloodstream infections caused by carbapenemase-producing Klebsiella pneumoniae: a clinical perspective.OXA β-lactamases.The role of conserved surface hydrophobic residues in the carbapenemase activity of the class D β-lactamases.
P2860
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P2860
Crystal structure of the OXA-48 beta-lactamase reveals mechanistic diversity among class D carbapenemases
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Crystal structure of the OXA-4 ...... y among class D carbapenemases
@ast
Crystal structure of the OXA-4 ...... y among class D carbapenemases
@en
Crystal structure of the OXA-4 ...... y among class D carbapenemases
@nl
type
label
Crystal structure of the OXA-4 ...... y among class D carbapenemases
@ast
Crystal structure of the OXA-4 ...... y among class D carbapenemases
@en
Crystal structure of the OXA-4 ...... y among class D carbapenemases
@nl
prefLabel
Crystal structure of the OXA-4 ...... y among class D carbapenemases
@ast
Crystal structure of the OXA-4 ...... y among class D carbapenemases
@en
Crystal structure of the OXA-4 ...... y among class D carbapenemases
@nl
P2093
P50
P3181
P1476
Crystal structure of the OXA-4 ...... y among class D carbapenemases
@en
P2093
Andrea Tafi
Francesco Giuliani
Luca Bellucci
Maurizio Botta
P3181
P356
10.1016/J.CHEMBIOL.2009.04.010
P50
P577
2009-05-29T00:00:00Z