3D architecture of DNA Pol α reveals the functional core of multi-subunit replicative polymerases
about
The Eukaryotic Replisome Goes Under the MicroscopeEukaryotic DNA polymerase ζThe architecture of a eukaryotic replisome.Emerging critical roles of Fe-S clusters in DNA replication and repair.Structure of a DNA Polymerase -Primase Domain That Docks on the SV40 Helicase and Activates the Viral PrimosomeMechanism for priming DNA synthesis by yeast DNA Polymerase αStructure, function, and tethering of DNA-binding domains in σ54transcriptional activatorsStructural Basis for the Interaction of a Hexameric Replicative Helicase with the Regulatory Subunit of Human DNA Polymerase -PrimaseA conserved motif in the C-terminal tail of DNA polymerase α tethers primase to the eukaryotic replisome.Evolution of replicative DNA polymerases in archaea and their contributions to the eukaryotic replication machineryEukaryotic DNA polymerases require an iron-sulfur cluster for the formation of active complexesDNA polymerases at the eukaryotic fork-20 years laterDNA polymerase δ and ζ switch by sharing accessory subunits of DNA polymerase δA novel variant of DNA polymerase ζ, Rev3ΔC, highlights differential regulation of Pol32 as a subunit of polymerase δ versus ζ in Saccharomyces cerevisiaeShared active site architecture between archaeal PolD and multi-subunit RNA polymerases revealed by X-ray crystallographyMechanism of Concerted RNA-DNA Primer Synthesis by the Human PrimosomeFunctional mapping of the fission yeast DNA polymerase delta B-subunit Cdc1 by site-directed and random pentapeptide insertion mutagenesis.An iron-sulfur cluster in the polymerase domain of yeast DNA polymerase ε.The C-terminal domain of the DNA polymerase catalytic subunit regulates the primase and polymerase activities of the human DNA polymerase α-primase complexA specific docking site for DNA polymerase {alpha}-primase on the SV40 helicase is required for viral primosome activity, but helicase activity is dispensableStructural basis for inhibition of DNA replication by aphidicolinArchaeology of eukaryotic DNA replicationCrystal structure of the human primaseThe CDC13-STN1-TEN1 complex stimulates Pol α activity by promoting RNA priming and primase-to-polymerase switch.Crystal Structure of the Human Pol α B Subunit in Complex with the C-terminal Domain of the Catalytic Subunit.StructMap: Elastic Distance Analysis of Electron Microscopy Maps for Studying Conformational ChangesPol31 and Pol32 subunits of yeast DNA polymerase δ are also essential subunits of DNA polymerase ζ.Virtual interactomics of proteins from biochemical standpoint.A four-subunit DNA polymerase ζ complex containing Pol δ accessory subunits is essential for PCNA-mediated mutagenesisReplicative DNA polymerases.Proficient Replication of the Yeast Genome by a Viral DNA PolymeraseDivalent ions attenuate DNA synthesis by human DNA polymerase α by changing the structure of the template/primer or by perturbing the polymerase reaction.Competition of zinc ion for the [2Fe-2S] cluster binding site in the diabetes drug target protein mitoNEET.Structural insights into yeast DNA polymerase delta by small angle X-ray scattering.Modulation of mutagenesis in eukaryotes by DNA replication fork dynamics and quality of nucleotide pools.Versatility of Approximating Single-Particle Electron Microscopy Density Maps Using Pseudoatoms and Approximation-Accuracy ControlHuman Pol ζ purified with accessory subunits is active in translesion DNA synthesis and complements Pol η in cisplatin bypass.Elaborated Action of the Human Primosome.The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transportDNA replication and homologous recombination factors: acting together to maintain genome stability.
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P2860
3D architecture of DNA Pol α reveals the functional core of multi-subunit replicative polymerases
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
3D architecture of DNA Pol α r ...... ubunit replicative polymerases
@ast
3D architecture of DNA Pol α r ...... ubunit replicative polymerases
@en
3D architecture of DNA Pol α r ...... ubunit replicative polymerases
@nl
type
label
3D architecture of DNA Pol α r ...... ubunit replicative polymerases
@ast
3D architecture of DNA Pol α r ...... ubunit replicative polymerases
@en
3D architecture of DNA Pol α r ...... ubunit replicative polymerases
@nl
prefLabel
3D architecture of DNA Pol α r ...... ubunit replicative polymerases
@ast
3D architecture of DNA Pol α r ...... ubunit replicative polymerases
@en
3D architecture of DNA Pol α r ...... ubunit replicative polymerases
@nl
P2093
P2860
P3181
P356
P1433
P1476
3D architecture of DNA Pol alp ...... ubunit replicative polymerases
@en
P2093
Luca Pellegrini
Rafael Núñez-Ramírez
Sebastian Klinge
P2860
P304
P3181
P356
10.1038/EMBOJ.2009.150
P407
P50
P577
2009-06-04T00:00:00Z