Structural Basis of the CD8 /MHC Class I Interaction: Focused Recognition Orients CD8 to a T Cell Proximal Position
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The multiple roles of the CD8 coreceptor in T cell biology: opportunities for the selective modulation of self-reactive cytotoxic T cellsAffinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complexStructural basis of mouse cytomegalovirus m152/gp40 interaction with RAE1 reveals a paradigm for MHC/MHC interaction in immune evasionForce measurements of TCR/pMHC recognition at T cell surfaceThe structure of mouse cytomegalovirus m04 protein obtained from sparse NMR data reveals a conserved fold of the m02-m06 viral immune modulator family.Versatile strategy for controlling the specificity and activity of engineered T cells.Development of new vaccines and drugs for TB: limitations and potential strategic errorsHow the virus outsmarts the host: function and structure of cytomegalovirus MHC-I-like molecules in the evasion of natural killer cell surveillanceCrystallization and preliminary X-ray crystallographic studies of swine CD8αInteraction of streptavidin-based peptide-MHC oligomers (tetramers) with cell-surface TCRsCD8αα and -αβ isotypes are equally recruited to the immunological synapse through their ability to bind to MHC class I.A nonclassical MHC class I U lineage locus in zebrafish with a null haplotypic variantSwitch-mediated activation and retargeting of CAR-T cells for B-cell malignancies.Integrin triplets of marine sponges in the murine and human MHCI-CD8 interface and in the interface of human neural receptor heteromers and subunits.The structural basis of chicken, swine and bovine CD8αα dimers provides insight into the co-evolution with MHC I in endotherm species.Structural and biophysical insights into the role of CD4 and CD8 in T cell activation.Duality of the murine CD8 compartment.The molecular determinants of CD8 co-receptor function.The structural basis of αβ T-lineage immune recognition: TCR docking topologies, mechanotransduction, and co-receptor function.Strict Major Histocompatibility Complex Molecule Class-Specific Binding by Co-Receptors Enforces MHC-Restricted αβ TCR Recognition during T Lineage Subset CommitmentCodification of bidentate pMHC interaction with TCR and its co-receptor.The sequence signature of an Ig-foldCD8 controls T cell cross-reactivity.Single-nucleotide polymorphisms in CD8A and their associations with T lymphocyte subpopulations in pig.Recognition of class I MHC by a rat Ly49 NK cell receptor is dependent on the identity of the P2 anchor amino acid of bound peptide.TCR Signaling Emerges from the Sum of Many PartsCD8-β ADP-ribosylation affects CD8(+) T-cell function.Effects of Cross-Presentation, Antigen Processing, and Peptide Binding in HIV Evasion of T Cell Immunity.Structure of the human MHC-I peptide-loading complex.Conservation of sequence motifs suggests that the nonclassical MHC class I lineages CD1/PROCR and UT were established before the emergence of tetrapod species.Dynamics of free versus complexed β2-microglobulin and the evolution of interfaces in MHC class I molecules.Empty conformers of HLA-B preferentially bind CD8 and regulate CD8+ T cell function.Structure of MHC class I-like MILL2 reveals heparan-sulfate binding and interdomain flexibility
P2860
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P2860
Structural Basis of the CD8 /MHC Class I Interaction: Focused Recognition Orients CD8 to a T Cell Proximal Position
description
2009 nî lūn-bûn
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2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Structural Basis of the CD8 / ...... to a T Cell Proximal Position
@ast
Structural Basis of the CD8 / ...... to a T Cell Proximal Position
@en
Structural Basis of the CD8 / ...... to a T Cell Proximal Position
@nl
type
label
Structural Basis of the CD8 / ...... to a T Cell Proximal Position
@ast
Structural Basis of the CD8 / ...... to a T Cell Proximal Position
@en
Structural Basis of the CD8 / ...... to a T Cell Proximal Position
@nl
prefLabel
Structural Basis of the CD8 / ...... to a T Cell Proximal Position
@ast
Structural Basis of the CD8 / ...... to a T Cell Proximal Position
@en
Structural Basis of the CD8 / ...... to a T Cell Proximal Position
@nl
P2093
P2860
P3181
P356
P1476
Structural Basis of the CD8 / ...... to a T Cell Proximal Position
@en
P2093
David H Margulies
Kannan Natarajan
P2860
P304
P3181
P356
10.4049/JIMMUNOL.0901276
P407
P577
2009-08-15T00:00:00Z