Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism - Wikidata - thesis-toulmin - TriplyDB

Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism

Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism

http://www.wikidata.org/entity/Q27656957

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Structural Features of Ion Transport and Allosteric Regulation in Sodium-Calcium Exchanger (NCX) Proteins Ca2+ regulation of ion transport in the Na+/Ca2+ exchanger NMR structure note: solution structure of Ca²⁺ binding domain 2B of the third isoform of the Na⁺/Ca²⁺ exchanger Uniqueness of models from small-angle scattering data: the impact of a hydration shell and complementary NMR restraints.Crystal structures of progressive Ca2+ binding states of the Ca2+ sensor Ca2+ binding domain 1 (CBD1) from the CALX Na+/Ca2+ exchanger reveal incremental conformational transitions.Structure-based dynamic arrays in regulatory domains of sodium-calcium exchanger (NCX) isoforms.An amphipathic α-helix directs palmitoylation of the large intracellular loop of the sodium/calcium exchanger A common Ca2+-driven interdomain module governs eukaryotic NCX regulation Ca2+-dependent structural rearrangements within Na+-Ca2+ exchanger dimers.Molecular basis of calpain cleavage and inactivation of the sodium-calcium exchanger 1 in heart failure.Ca2+ binding alters the interdomain flexibility between the two cytoplasmic calcium-binding domains in the Na+/Ca2+ exchanger Proton-sensing Ca2+ binding domains regulate the cardiac Na+/Ca2+ exchanger.Residues 248-252 and 300-304 of the cardiac Na+/Ca2+ exchanger are involved in its regulation by phospholemman.Calmodulin Interacts with the Sodium/Calcium Exchanger NCX1 to Regulate Activity.The interaction of Ca2+ with sarcomeric proteins: role in function and dysfunction of the heart Palmitoylation of the Na/Ca exchanger cytoplasmic loop controls its inactivation and internalization during stress signaling Structural arrangement of the intracellular Ca2+ binding domains of the cardiac Na+/Ca2+ exchanger (NCX1.1): effects of Ca2+ binding.Development of a high-affinity peptide that prevents phospholemman (PLM) inhibition of the sodium/calcium exchanger 1 (NCX1).Survey of the year 2009: applications of isothermal titration calorimetry.Electromechanical coupling in the cardiac myocyte; stretch-arrhythmia feedback.Structural and dynamic aspects of Ca2+ and Mg2+ binding of the regulatory domains of the Na+/Ca2+ exchanger.Recent structural and functional insights into the family of sodium calcium exchangers.Function and regulation of the Na+-Ca2+ exchanger NCX3 splice variants in brain and skeletal muscle.Modeling Na+-Ca2+ exchange in the heart: Allosteric activation, spatial localization, sparks and excitation-contraction coupling.CING: an integrated residue-based structure validation program suite.Population shift underlies Ca2+-induced regulatory transitions in the sodium-calcium exchanger (NCX).Essential role of the CBD1-CBD2 linker in slow dissociation of Ca2+ from the regulatory two-domain tandem of NCX1.Structure-dynamic determinants governing a mode of regulatory response and propagation of allosteric signal in splice variants of Na+/Ca2+ exchange (NCX) proteins.Molecular determinants of pH regulation in the cardiac Na+-Ca2+ exchanger.

P2860

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P2860

Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism

http://www.wikidata.org/entity/Q27656957

description

2009 nî lūn-bûn

@nan

2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism

@ast

Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism

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Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism

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type

label

Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism

@ast

Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism

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Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism

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prefLabel

Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism

@ast

Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism

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Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism

@en

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Alice Foarce

http://www.w3.org/2001/XMLSchema#string

Geerten W Vuister

http://www.w3.org/2001/XMLSchema#string

Jan Aelen

http://www.w3.org/2001/XMLSchema#string

Mark Hilge

http://www.w3.org/2001/XMLSchema#string

P2860

Electrostatics of nanosystems: application to microtubules and the ribosome

The second Ca2+-binding domain of the Na+ Ca2+ exchanger is essential for regulation: crystal structures and mutational analysis.

Protein NMR structure determination with automated NOE assignment using the new software CANDID and the torsion angle dynamics algorithm DYANA

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

The program XEASY for computer-supported NMR spectral analysis of biological macromolecules

The crystal structure of the primary Ca2+ sensor of the Na+/Ca2+ exchanger reveals a novel Ca2+ binding motif

Synaptotagmin-syntaxin interaction: the C2 domain as a Ca2+-dependent electrostatic switch

Cloning of a third mammalian Na+-Ca2+ exchanger, NCX3

Functional comparison of the three isoforms of the Na+/Ca2+ exchanger (NCX1, NCX2, NCX3)

Expression of the Na(+)/Ca(2+) exchanger in skeletal muscle

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34

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106

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Anastassis Perrakis

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2009-08-25T00:00:00Z

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26729056

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19667209

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2732890

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