Lateral opening of a translocon upon entry of protein suggests the mechanism of insertion into membranes
about
Internal lipid architecture of the hetero-oligomeric cytochrome b6f complexSecA, a remarkable nanomachineHydrogen bond dynamics in membrane protein functionStructure of the Sec61 channel opened by a signal sequenceStructures of the E. coli translating ribosome with SRP and its receptor and with the translocon.Cryo-EM structure of the ribosome–SecYE complex in the membrane environmentStructure of the SecY channel during initiation of protein translocationStructure of the Mammalian Ribosome-Sec61 Complex to 3.4 Å ResolutionStructures of the Sec61 complex engaged in nascent peptide translocation or membrane insertionVisualization of a polytopic membrane protein during SecY-mediated membrane insertionMembrane Protein Structure, Function, and Dynamics: a Perspective from Experiments and Theory.Structure of the native Sec61 protein-conducting channelStructure of the quaternary complex between SRP, SR, and translocon bound to the translating ribosome.Structural and functional profiling of the lateral gate of the Sec61 transloconMapping of the SecA signal peptide binding site and dimeric interface by using the substituted cysteine accessibility methodFree energy of nascent-chain folding in the translocon.Mechanisms of integral membrane protein insertion and foldingApolar surface area determines the efficiency of translocon-mediated membrane-protein integration into the endoplasmic reticulum.Hydrophobic blocks facilitate lipid compatibility and translocon recognition of transmembrane protein sequencesConserved SMP domains of the ERMES complex bind phospholipids and mediate tether assemblyThe bacterial Sec-translocase: structure and mechanism.Marginally hydrophobic transmembrane α-helices shaping membrane protein folding.Anomalous behavior of water inside the SecY transloconDirect simulation of early-stage Sec-facilitated protein translocationBacterial protein translocation requires only one copy of the SecY complex in vivo.Emerging themes in SecA2-mediated protein export.Regulation of multispanning membrane protein topology via post-translational annealing.Structurally detailed coarse-grained model for Sec-facilitated co-translational protein translocation and membrane integrationLong-timescale dynamics and regulation of Sec-facilitated protein translocation.Mobility of the SecA 2-helix-finger is not essential for polypeptide translocation via the SecYEG complexA gating motif in the translocation channel sets the hydrophobicity threshold for signal sequence function.Protein translocation across the rough endoplasmic reticulum.Reconciling the roles of kinetic and thermodynamic factors in membrane-protein insertion.Determination of the Oligomeric State of SecYEG Protein Secretion Channel Complex Using in Vivo Photo- and Disulfide Cross-linking.Crystal structure of a substrate-engaged SecY protein-translocation channelStoichiometry of SecYEG in the active translocase of Escherichia coli varies with precursor species.Cotranslational folding of membrane proteins probed by arrest-peptide-mediated force measurements.Functional asymmetry within the Sec61p translocon.Transmembrane segments form tertiary hairpins in the folding vestibule of the ribosome.An allosteric Sec61 inhibitor traps nascent transmembrane helices at the lateral gate.
P2860
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P2860
Lateral opening of a translocon upon entry of protein suggests the mechanism of insertion into membranes
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Lateral opening of a transloco ...... sm of insertion into membranes
@ast
Lateral opening of a transloco ...... sm of insertion into membranes
@en
Lateral opening of a transloco ...... sm of insertion into membranes
@nl
type
label
Lateral opening of a transloco ...... sm of insertion into membranes
@ast
Lateral opening of a transloco ...... sm of insertion into membranes
@en
Lateral opening of a transloco ...... sm of insertion into membranes
@nl
prefLabel
Lateral opening of a transloco ...... sm of insertion into membranes
@ast
Lateral opening of a transloco ...... sm of insertion into membranes
@en
Lateral opening of a transloco ...... sm of insertion into membranes
@nl
P2860
P356
P1476
Lateral opening of a transloco ...... sm of insertion into membranes
@en
P2093
Robert M Stroud
P2860
P304
17182-17187
P356
10.1073/PNAS.1012556107
P407
P577
2010-09-20T00:00:00Z